Cindy Willis Email and Phone Number

• Scientific and Medical Writing: drafting, revising, and editing scientific and medical documents (e.g. abstracts, posters, presentation slides, journal manuscripts, non-clinical study reports) for biotechnology companies, contract research organizations, research-based clinicians, and academics. • Scientific Writing Instructor: Conducted a 2-day, highly rated and proven scientific writing course teaching scientists to communicate effectively and efficiently about their research.• Biotech Consultant: Provided research support consultation services for the biopharmaceutical industry for conference coverage, target assessment, literature summaries, due diligence, and interpretation of data sets for oncology, autoimmune, and inflammatory diseases.

Research project team leader and research analytics• Led 2 multi-disciplinary, multi-site, team-based projects to screen and develop large-molecule drugs for autoimmune and inflammatory indications • Provided preclinical model expertise to build therapeutic rationale for autoimmune and inflammatory diseases• Supervised and mentored 2-person teams, including associates, scientists and international PhD student interns• Led and organized multi-disciplinary working groups to develop new targets and biomarkers for lupus and COPD• Managed and analyzed complex flow cytometry and microarray data sets from mouse models of lupus and human lupus blood samples to identify new targets for treating lupus• Designed and conducted various T-cell, B-cell, and macrophage assays for target validation, drug coverage, and drug candidate screening• Designed and coordinated non-human primate studies with contract research organizations for immune challenge, arthritis, asthma, and COPD models• Initiated and coordinated contracts with vendors to obtain fresh human blood, induced sputum, and lungs for target discovery and biomarker development• Initiated and supervised several contracts with collaborators at US and European universities to test concepts and potential drug molecules using technologies outside of Amgen’s expertiseCo-instructor for Scientific Writing Course • Conceived and designed a 2-day scientific writing and reviewing course customized for Amgen Research• Coordinated and co-taught the scientific writing course for all Amgen research sites, conducting several courses per yearVoting Member of Institutional Animal Care and Use Committee • 3-site IACUC committee responsible for reviewing and approving animal use protocols, conducting vivarium quarterly inspections, and updating program guidelines

• Trained and supervised peers in transgenic and knockout mouse production and maintenance of colonies• Had increasing responsibility for determining phenotypes of transgenic and knockout mice. Led team efforts to design and conduct studies to understand transgene and knockout gene effects. • Trained and mentored PhD post-docs in techniques for assessing knockout mouse phenotypes; designed and implemented in vivo and in vitro assays for assessing complex knockout mouse phenotypes• Lead biology representative on a multi-disciplinary, team-based project with responsibility to design and conduct in vivo immune challenge and autoimmunity models to validate CD30L

• Developed new mouse embryonic stem cell lines. Cloned mouse knockout DNA constructs, screened and produced mouse embryonic stem cells to produce knockout mice.• Microinjected mouse embryos to create mice genetically deficient in novel Immunex molecules • Organized breeding schemes for double and triple knockout mouse colonies• Microinjected mouse oocytes to produce transgenic mice expressing several novel Immunex cytokines, cytokine receptors, and TNF family members• Genotyped transgenic mice, screened mice for transgene expression, and maintained breeding and production colonies of transgenic mice• Cloned and produced DNA transgenic constructs for microinjection