RNA Technologies and Therapeutics Inc. (RNA T&T) is a privately held company headquartered in Montreal, Canada, that specializes in the design, optimization and small-mid scale production (mg to g) of RNA including nucleoside modified messenger RNA, RNA formulation and the development of mRNA-based technologies/therapeutics. We are committed to address infrastructural barrier to clinical and translational research in vaccine development, gene therapy, stem cell reprograming, and other non-viral gene therapy-based applications by providing high quality in vitro transcribed RNA (e.g., mRNA, lncRNA, and circRNA) and targeted lipid-based (LNPs) and hybrid delivery systems, or nanoparticles, to the biotech industry, and academic partners. Our business model, current research and development efforts, and therapeutic pipeline aim to develop innovative mRNA-based therapeutics/technologies that will improve the health and wellbeing of individuals around the world.

Company Vision - Understanding the Molecular Genetics’ inception of diseases leads to novel therapeutic diagnostics and cures.Mission Statement - Creating early diagnostic tools and developing novel therapeutic solutions for targeted chronic disabling diseases in pediatric and adult populationsActual Projects - Developing both an early Osteoarthritis therapeutic small molecule and diagnostic test, to stop and potentially reverse the OA pathogenesis process in early diagnosed OA population.

Ortho Regenerative Technologies Inc. is an orthopedic biotechnology company developing novel therapeutic tissue repair devices to dramatically improve the success rate of Sports Medicine Surgerieswww.orthorti.com

Proteomics Biomarkers Assays, analytical services and clinical DiagnosticsMission:Providing the broader PHARMA / BIOTECH scientific community with tools and technologies to facilitate proteomics research and translating proteomics research into advanced diagnostics for clinical world wide market opportunities, that will benefit patients

Axcelon Dermacare Inc. is a majority owned subsidiary of Axcelon Biopolymers Corp. based in Toronto, Ontario, and focusing on developing advanced wouncare products and technologies.Axcelon Dermacare lead product is NanodermTM, a unique woundcare product indicated for a variety of acute wound treatments including burns and dermabrasions as well as for chronic wounds such as venous leg ulcers, pressure ulcers and diabetic foot ulcers. Nanoderm™ has unique Health economic advantages over other competitive wound dressings with a one-time application dressing in most wound types. The product additionally provides a suitable barrier to infections while allowing gaseous exchange, some exudate evaporation and pain alleviation.Axcelon has furthermore developed Nanoderm™Ag; a patented biopolymer wound care dressing with slow release silver for infected wounds. Nanoderm™Ag is planned to be launched in 2017.

Axcelon Biopolymers Corporation is an innovative biomaterials company focused on leveraging its unique Bacterial Nanocellulose (BNC) platform technology to develop high value products for wound care, medical devices, tissue engineering, and industrial applications.

Helping, guiding and supporting the CEO with corporate vision, development and organization.

International Commercialization Plan and implementation.Commercialization options and recommendation.Marketing and sales strategies.Partnering search and alliances.

Established in 1995 and traded on the TSX Venture since 2004, BioSyntech has created and developed innovative biotherapeutic thermogels for regenerative medicine (tissue repair) and therapeutic delivery, which appeal unmet medical needs.• Financing – IPO and private investments of over $45 million over 4 years• Clinical – Built a team and structure to execute Canadian and International clinical trials (Canada, Europe and Korea) for two products (cartilage repair & wound healing) and with two others in the pipeline• Operations – Built the teams, structures and physical plant to meet manufacturing needs, and QA/QC regulatory requirements for the clinical trial programs and the early commercialization phase• Obtained ISO-9001 and ISO 13485 certifications• Business Development – Secured commercial partnerships in Asia and managed negotiations with worldwide partners and prepared the company to its pre-commercialization phase

Genzyme BioSurgery liaison for international marketing distributorsLead all aspects of development for the international orthopaedic business including:• International marketing and sales strategies and plans in existing and new markets: evaluation, creation and execution• Managing existing and creating new market distribution partnerships• Establishing new corporate offices and direct marketing & sales organizations in South East Asia, including Australia, Malaysia, Singapore • Scientific and clinical training with distributors and their local medical communities• Preparation and presentation of scientific and clinical lectures on viscosupplementation to orthopaedic surgeons, and rheumatologists in Canada, France, Sweden, Greece, England, Singapore, Malaysia, Thailand, Hong Kong, India, LATAM, the Middle East and others• Training of physicians to become speakers in Canada, Europe, and Asia• Training of Corporate marketing and sales force staff in USA, Europe, LATAM, and Canada

• Reclaimed the business from International Pharma licensee to start a new Genzyme/Biomatrix (merger) Canadian marketing and sales team in Canada• Achieved remarkable results trending from -35% in 1999 to + 45% in 2001• Developed new European markets• Marketing and sales liaison between Headquarters and European partners• Delivered Scientific, clinical and marketing viscosupplementation courses for medical, marketing and sales; including staff and partners in Europe as well as in Central and South America

• Developed infertility clinics in the Province of Quebec• Trained medical staff on gonadotrophins usage for in vitro-fertilization• Developed patient education programs in partnership with local clinics and created media kits to enhance awareness

• Pharma products promotion in Quebec hospitals• Sales promotion in Cardiology, Rheumatology, Orthopaedic surgery, Dermatology, Anesthesia, Ob/Gyn, etc.• Won National Sales Awards 1988, Best in Canada