Study of the Group 2 Innate Lymphoid Cells (ILC2s) in type 2 autoimmunity.

Study the activity of RAD140 against ESR1 fusions in ER+ breast cancer PDX and cell line models.ER+ Brest cancer is one of the most common diseases among women worldwide. Endocrinetherapy targets the ER signaling pathways throught several mechanisms. However, some patients become resistant and develop metastasis. One of the mechanisms underlying such resistance is ESR1 fusion events. We aimed to evaluate the activity of the SARM RAD140 against ESR1 fusions as an alternative therapeutical strategy.

Study the post-transcriptional regulatory mechanisms of GRK2 through its 5'UTR region dependent on sexual hormones.Bibliographic search to identify potential proteins that may interact with GRK2 mRNA through its 5'UTR in the ribosome scanning process during protein translation.

Rotation thought several departments (Microbial, Immunology, Biochemistry, Tumor Biomarkers) to study the complex interplay between biochemical and clinical test to diagnose patients in a more clinical environment.