Highly self-motivated and detail-oriented organic chemist, with excellent skills in synthetic route design, multi-step organic synthesis, process optimization, impurity control and mitigation, crystallization etc. Recognized as a creative, enthusiastic and hard-working problem solver for tough synthetic problems, with 13+years of industrial experience, evidenced by publications in leading peered-reviewed journals and as a co-inventor on drug discovery/process patentsi) Synthetic route scouting/design and chemical process optimizationii) Rapid scale up of API from multi-gram to kilograms, move DC to IND enabling stageiii) Years of experience of working/managing cGMP production both in kilolab and with CDMOsiv) successfully delivery of registration batchesv) Polymorphic screening, conversion and characterization of different crystal forms.vi) C14-radiolabel synthesisvii) authoring regulatory filing documents, such as IND, RSM proposal etc
Listed skills include Chemical Process Research And Optimization, Organic Synthesis, Clinical Development, Medicinal Chemistry, and 12 others.