Conor Mccaffrey Email & Phone Number

Ireland

Dunboyne, County Meath, Ireland

Dunboyne, County Meath, Ireland

• Capability Champion, ensuring sufficient cover is available for each testing method/quality metric.
• Project Management of all tasks undertaken by QC Biochemistry team.
• Build out testing/review schedule and development goals for QC Biochemistry Team.
• Facilitate weekly audit walkthrough with Site Leadership Team as SME for ELISA methods.
• Support authoring and review of documents relating to Tech Transfer and method validation and drive continuous improvement through CAPA / Change Control process.

Dunboyne, County Meath, Ireland

• Facilitate daily QC Tier touchpoints.
• Present Weekly Safety Moments for QC.
• Project Management of Analytical Tech Transfer to QC Biochem/final approval of transfer documentation
• Trained as a Risk Facilitator for MSD Dunboyne Site.
• Audit Representative for QC Biochemistry Lab/ Driving Lab Readiness.
• Update SOPs/WIs on Quality Docs/MIDAS and approve methods on ELN/LIMS.

Dublin, Leinster, Ireland

• Performing drug substance/drug product testing using HPLC methods including Reverse Phase, Affinity Chromatography with Empower software.
• Analyst for transfer of UPLC/HPLC/ELISA method testing of Ultomiris to Alexion Dublin site.
• Analysis of PS80 Concentration using UV-Vis.
• Host Cell Protein analysis through ELISA.
• Isoelectric focussing analysis of Soliris samples.
• Act as site subject matter expert for RP-HPLC, HCP analysis and PS80 testing.

• Carrying out stability testing, raw material testing and final container testing of all incoming materials according to cGMP and quality systems.
• Preparation of Stability Reports and updating SOPs and other relevant documentation as necessary to ensure compliance with quality systems and cGMP guidelines.
• Training of new and existing biochemists on site on various processes.
• Maintenance and calibration of laboratory equipment and monitoring of temperatures within QC laboratory to ensure operations are carried out within required specifications.
• Documenting all manufactured intermediate materials and final products on the online resource planning system.
• Revising and reviewing documentation, recommending improvements and implementing changes to ensure up to standard quality systems and MDSAP/ISO compliance prior to submission to quality assurance department.

Maynooth, Co Kildare And Dunboyne, Co. Meath, Ireland

• Research identified key changes in enzyme production, tissue morphology and cell death levels which impacted the fluidity of the intestinal tract, gut microbiology and ultimately as a measure of animal productivity.
• Quantifying expression of pro- and anti-inflammatory cytokines on cell/tissue lysate and serum through ELISA.
• Analysing levels of cell death in intestinal sections though immunohistochemical analyses and TUNEL staining for apoptosis and necroptosis.
• Examining expression levels of components relating to TLR4, TLR9 signalling pathways through SDS-PAGE and Western Blot.

Dublin City University

This project consisted of identifying and analysing recombinant antibody fragments specific for HER2 for eventual incorporation into a revolutionary point-of-care device for prostate cancer diagnosis. Polyclonal and scFv antibodies derived from eggs were analysed using SDS-PAGE, Western blotting and various ELISA formats in order to determine.

Ghent, Belgium

I was awarded a lucrative and highly sought-after placement in Ghent University Hospital. My project consisted of optimising expression levels of FFPE patient samples to determine optimal parameters. I also investigated the efficacy of mismatch blockers of allele-specific qPCR efficiency.

M.Sc., Immunology

B.Sc. Genetics And Cell Biology, School Of Biotechnology, 1St Class Honours

Activities and Societies: Music Society, GAA, Swimming, Shave or Dye Foundation, DCU Ultimate

Higher Diploma, Data Analytics, 1:1

The course covers such skills as automating manual spreadsheet-oriented data analysis processes, converting large data sets into.