Matthew Corley Email & Phone Number

South San Francisco, California, US

Sunnyvale, California, US

Sunnyvale, California, US

Menlo Park, California, US

• Synthego's mission is to turn biology into an information science by enabling automated genome engineering at scale. As a software engineer, I collaborated with engineers and scientists across the organization to.
• Design and implementation of core microservices using Python and gRPC, e.g. a real-time notication service guaranteeing at least-once, in-order delivery of asynchronous events to third party APIs.
• Migrating the core Django monolith, responsible for coordinating all activity in our robotic laboratories, from our on premises data center to the cloud (AWS EC2 and RDS).
• Hardening operation of our backend services, including: automated provisioning and deployment, centralized logging, instrumentation (metrics, distributed tracing), and real-time monitoring and alerting.

San Francisco, California, US

SignalFx is a highly available, streaming time series processing engine that ingests, stores, and analyzes billions of datapoints per day with end-to-end latency of a few seconds. Some of my contributions included:- Owning development and operation of the Kafka-based message bus supporting streaming data pipelines- Design and implementation of.

St. Louis, MO, US

• developed improved computational/statistical methods for the analysis and interpretation of next gen sequencing experiments (Python/Cython, SQLite; gaussian mixture models, negative bionomial regression)
• petabyte-­scale data mining, including the analysis of genomes from The Cancer Genome Atlas (TCGA) for 3,000+ patients across eight cancer types (Perl, R, Python)
• integrated analysis and visualization of epigenomic data using Python (numpy, scikitlearn, and matplotlib)

Grinnell, Iowa, US

• Managed a team of approximately 60 employees, including hiring, training and certification, scheduling, and payroll assistance.
• Resolved escalated service issues, requiring a detailed knowledge of Windows 7, OS X, and Linux distributions, computer networking, and intermediate hardware repair.
• Assisted with programming (PHP, SQL) and maintenance of an in-house employee management database and web portal.

Grinnell, Iowa, US

SUPERVISOR: Dr. Vida PraitisPROJECT SUMMARY: Forward genetic screens to dissect the molecular pathway by which the Golgi-linked Ca(2+) ATPase pmr-1 regulates cell migration and tissue organization during C. elegans gastrulation

Grinnell, Iowa, US

Multi­platform (Linux, Windows XP/Windows 7, Mac OSX) technical support on­site and by phone for over 1,600 students, faculty, and staff. Provided support for networking, hardware diagnostics/repair, data recovery, A/V setup and configuration, and system administration of academic computing resources (Linux-­based servers and LAN for Math & CS).

SUPERVISOR: Dr. Sarit SmolikovePROJECT SUMMARY: A Yeast-2-Hybrid Screen to Identify Novel Protein-Protein Interactions Regulating Disassembly of the Synaptonemal Complex in C. elegans meiosis; Protein Structure Prediction via Homology Modelling

SUPERVISOR: Dr. John LogsdonPROJECT SUMMARY: Comparative genomic analysis of meiotic protein evolution in putative ”ancient asexual” rotifer species; molecular phylogenetic tree construction using Bayesian inference

Master Of Science - Ms, Genome Sciences/Genomics

Bachelor Of Arts (B.A.), Biology

International Affiliate Student, Computational And Systems Biology