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• Technical background in engineering and scientific research, including design of experiments, data analysis, engineering design, modeling, simulation, and control algorithms.• Experience leveraging model-based design (MBD) for embedded medical devices.• Leadership experience building and leading technical and cross-functional teams, including establishing processes and structures based on an agile/lean framework.• Strong background in human physiology, particularly deep in glucose metabolism (and the pathophysiology associated with diabetes, both type 1 and type 2), as well as hemodynamics.• Thorough understanding of design control, risk assessment and regulatory requirements for medical devices.• Clinical research expertise, including development of clinical research protocols and clinical trial support.• Strong written and oral communications skills. Experience spans from journal papers through supporting documentation for regulatory submissions, from teaching and leading workshops through public speaking.• Experienced coach and mentor to junior staff.• Certified Master Change Manager for the Change Acceleration Process (CAP) and Green Belt trained in Design for Reliability and Manufacturability (Lean Six Sigma).• Interests include: systems engineering, design thinking, modeling and control, data science, lean development methodologies, lean six sigma, model-based design (MBD), change management, innovation, safety engineering, and the application of systems theory, modeling and control to medical, biological, and other complex systems.
Sf Bay Counseling
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Co-OwnerSf Bay Counseling May 2019 - PresentMany couples are unhappy or wonder if their relationship could be better. At SF Bay Counseling, we offer counseling and workshops to equip couples with the tools to create a healthy relationship and experience happiness in love.In partnership with my wife, a licensed marriage and family therapist, we operate SF Bay Counseling. I am in charge of the business's technology infrastructure, financials, and aspects of marketing.
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ConsultantCesar Palerm Consulting Aug 2018 - Present
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Director, Technical Product StrategySleep Number Labs Aug 2021 - Mar 2024San Jose, California, UsI led the strategy on the science and technology of connected sleep health, overseeing a portfolio of strategic research projects.I was involved in merger and acquisition (M&A) activities and external partnerships. Among the external partnerships was work with the Digital Medicine Society (DiME) to develop a core set of digital measures of sleep. Other partnerships included collaborations with external research groups. -
Director, Systems ThinkingBigfoot Biomedical Oct 2016 - Jul 2018Milpitas, California, UsI built a team to create a core competency to leverage Model-Based Development/Design in the research and development of medical devices to improve the lives of people with diabetes through the application of smart technology. The focus was from a systems-engineering perspective, down through the design and implementation of specific algorithms. At the system-level we focused on understanding the choices and tradeoffs of proposed designs, understanding emergent properties and ensuring a high degree of certainty on the performance and quality of the systems through modeling and simulation. At the detail level the algorithms developed were integrated into our devices through automatic code generation from the corresponding models.I also supported overall systems-level activities, including high-level system design, design risk analysis activities, as well as leading technical design reviews. -
Senior Principal ScientistMedtronic Diabetes Jun 2014 - Oct 2016I was involved in research and development of the MiniMed 670G product to automate insulin delivery based on glucose sensor data. More broadly my focus was on front-end development aimed at improving product features, ensuring safety, mathematical modeling, and algorithm development.In my role I was a spokesman for Medtronic Diabetes. I regularly presented on topics related to our technologies, in particular the development of an artificial pancreas system. I did this for physician visits at the Diabetes HQ, as well as for other geographies, including Spain, Germany and Latin America. I presented at external medical conferences within the United States, Brazil, Mexico and Spain.During my time with the systems engineering group I mentored and supervised a masters level student doing independent research (Anne Maas), whose work was related to physiology modeling related to meal dynamics and behavior. I also supervised and led various technical teams, and mentored younger engineers within the organization.I also maintained ongoing connections with people in the academic community who are engaged in work relevant to our own. Some of these have resulted in my participation as an external examiner for students completing the masters and doctorate degrees.
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Principal ScientistMedtronic Diabetes Aug 2007 - Jun 2014Minneapolis, Mn, UsI played a key role in the development of the Predictive Low Glucose Management (PGLM) algorithm, which is the main feature in the 640G pump. I set up the physiology modeling framework used in this project, which helped the team drive the design process using principles of set-based engineering. This framework also enabled us to test for multiple edge conditions, some of which emerged from the simulations and had not been anticipated by the team. This work resulted in several patent applications, some related to the algorithms, and others to metrics developed in the context of the design process to assess system performance.As a part of the closed loop development group my research focused on the development of closed-loop algorithms for insulin delivery to regulate blood glucose, both for patients with type 1 diabetes (ambulatory use), as well as those patients in critical care that require insulin (in hospital use). Work performed during this time was eventually incorporated into the MiniMed 670G product.I also mentored and supervised graduate student interns. -
Postdoctoral Research FellowUniversity Of California Santa Barbara Oct 2004 - Aug 2007Santa Barbara, Ca, UsDepartment of Chemical Engineering and the Biomolecular Science and Engineering Program at UCSB, mentored by Prof. Francis J. Doyle III.Research was a collaborative effort with the Sansum Diabetes Research Institute. Research focused on modeling and algorithm development to regulate blood glucose using continuous glucose sensors and a subcutaneous insulin infusion pump, using a model predictive control strategy. In prior research, I developed strategies that use run-to-run control to adjust basal insulin infusion and prandial insulin bolus dosing for individuals with type 1 diabetes on continuous insulin infusion pumps. Modeling work using clinical data includes the hyperinsulinemic-euglycemic clamp experimental protocol, as well as the incorporation of the circadian changes in insulin sensitivity.– Mentored a postdoctoral fellow.– Mentored students at the Ph.D. (three) and M.S. (one) levels.– Mentored and supervised three undergraduate students doing independent research. -
Guest InvestigatorSansum Diabetes Research Institute Oct 2004 - Aug 2007Santa Barbara, Ca, UsMentored by Lois Jovanovič, M.D.My work at SDRI involved the human subject clinical trial component of the research done in collaboration with UCSB. -
Postdoctoral FellowRensselaer Polytechnic Institute 2003 - 2004Troy, Ny, UsThe Isermann Department of Chemical and Biological Engineering, worked with Prof. B. Wayne Bequette.Developed, and characterized in silico, a method for real-time estimation of blood glucose and its application to the prediction and detection of hypoglycemia.– Mentored a student at the Ph.D. level.
Cesar Palerm, Ph.D. Skills
Cesar Palerm, Ph.D. Education Details
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Rensselaer Polytechnic InstituteEngineering Science -
Rensselaer Polytechnic InstituteMathematics -
Rensselaer Polytechnic InstituteElectrical Engineering -
Iteso Universidad Jesuita De GuadalajaraElectrical Engineering
Frequently Asked Questions about Cesar Palerm, Ph.D.
What company does Cesar Palerm, Ph.D. work for?
Cesar Palerm, Ph.D. works for Sf Bay Counseling
What is Cesar Palerm, Ph.D.'s role at the current company?
Cesar Palerm, Ph.D.'s current role is Systems thinker with ample experience in medical device R&D, from early stage research on through to commercialization..
What is Cesar Palerm, Ph.D.'s email address?
Cesar Palerm, Ph.D.'s email address is ce****@****ber.com
What is Cesar Palerm, Ph.D.'s direct phone number?
Cesar Palerm, Ph.D.'s direct phone number is +140871*****
What schools did Cesar Palerm, Ph.D. attend?
Cesar Palerm, Ph.D. attended Rensselaer Polytechnic Institute, Rensselaer Polytechnic Institute, Rensselaer Polytechnic Institute, Iteso Universidad Jesuita De Guadalajara.
What skills is Cesar Palerm, Ph.D. known for?
Cesar Palerm, Ph.D. has skills like Biomedical Engineering, Medical Devices, Matlab, Latex, Simulink, Mathematical Modeling, Control Systems, Lean Thinking, Model Based Development, Diabetes, Control Systems Design, Signal Processing.
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