Pipeline Development & Engineering:▪ Developed computational modules for NEOAG, a comprehensive neoantigen characterization pipeline.▪ Engineered scalable Nextflow workflows and resolved containerization issues.▪ Implemented best practices for modular package development and HPC optimization.Data Curation & Modeling:▪ Established SQL databases and automated feature computation for immunogenicity prediction.▪ Developed model comparison heuristics and centralized code repository for team collaboration.Tumor Mutation Analysis:▪ Developed novel methods for normalized tumor mutation burden estimation.▪ Analyzed tumor neoantigen landscapes across diverse cohorts, informing immunotherapy strategies.Collaborative Research:▪ Collaborated with cross-functional teams and external partners on personalized DNA vaccine trials.▪ Presented findings at team seminars and contributed to peer-reviewed publications.

Genomics Data Analysis & Computational Pipeline Engineering:▪ Engineered custom computational pipelines for analyzing human, mouse, and yeast genomes from diverse experiments.▪ Developed and optimized CRISPR/Cas9 guide RNA libraries, enhancing experimental efficiency.▪ Contributed to the publication of prestigious Nature articles and multiple successful grant proposals.Visualization & Tool Development:▪ Created multiGIviewer, an interactive Shiny web application for visualizing genetic interaction data from CRISPR/Cas9 experiments.▪ Released fedup, an R Bioconductor package for versatile pathway analysis, aiding in the interpretation of genomic datasets.

▪ Annotated textual de-identified patient data for use in large machine learning projects▪ Validated the clinical significance of AI algorithm predictions

▪ Analyzed various cancer histology slides and tissue samples▪ Developed and implemented histological quality control procedures▪ Prepared reports and presentations for the molecular pathology team