Daniel Carvalho Email & Phone Number

United States

Cambridge, Massachusetts, United States

Cambridge, Massachusetts, United States

Performed data analysis on single-nucleus sequencing (snRNA-seq) data related to neurodegenerative diseases, particularly Alzheimer's disease. Developed R Shiny applications to support scientific discovery for research projects in the field of neurodegenerative diseases. Conducted analyses on snRNA-seq datasets to investigate various aspects such as the impact of genetic factors on disease progression and the interaction between gene expressions in animal models. Collaborated with wet lab… Show more Performed data analysis on single-nucleus sequencing (snRNA-seq) data related to neurodegenerative diseases, particularly Alzheimer's disease. Developed R Shiny applications to support scientific discovery for research projects in the field of neurodegenerative diseases. Conducted analyses on snRNA-seq datasets to investigate various aspects such as the impact of genetic factors on disease progression and the interaction between gene expressions in animal models. Collaborated with wet lab scientists to provide insights and support their research efforts. Show less

Ridgefield, Connecticut, United States

Analyzed single-cell RNA sequencing (scRNA-seq) data of human, cynomolgus monkey, and other tox species to provide in-silico support for drug safety decisions in the Computational Toxicology lab of the Integrative Toxicology group within the Non-clinical Drug Safety department. Analyses included—alignment of scRNA-seq reads to relevant genomes, use of programming languages (R, Python, bash), and figure generation. In addition, an integrated analysis of tox species’ scRNA-seq data will be… Show more Analyzed single-cell RNA sequencing (scRNA-seq) data of human, cynomolgus monkey, and other tox species to provide in-silico support for drug safety decisions in the Computational Toxicology lab of the Integrative Toxicology group within the Non-clinical Drug Safety department. Analyses included—alignment of scRNA-seq reads to relevant genomes, use of programming languages (R, Python, bash), and figure generation. In addition, an integrated analysis of tox species’ scRNA-seq data will be provided via an in-house built R Shiny application. The data for this application were integrated using Scanpy and scVI in a comprehensive Jupyter Notebook developed from scratch. Show less

Boston, Massachusetts, United States

Processed and analyzed RNA-seq data for mRNA, lncRNA, and circRNA from post-mortem brain and placental tissue of people with alcoholism and of people with opioid addiction. Data analysis included use of RNA-seq pipelines to process raw reads as well as generation of figures for corresponding manuscripts in R.

Monmouth Junction, New Jersey, United States

Piscatway, Nj

Oligo synthesis lab technician. Maintained and operated oligo synthesizers for gene synthesis.

Galloway, New Jersey, United States

Determined a synthetic route for a novel fluorinated pi-extended carbazole derivative under the supervision of Dr. Erin E. Brown, PhD.

Master Of Science - Ms, Bioinformatics

Bachelor Of Science - Bs, Biochemistry And Molecular Biology

Biochemistry Molecular Biology, Bs, General