Damber Thapa Email & Phone Number

Toronto, On, Ca

Toronto

The Center for Advanced Diffusion-Wave and Photoacoustic Technologies (CADIPT) at the University of Toronto is a research lab focused on the developing photothermal and photoacoustic imaging technologies for biomedical applications. The lab integrates advanced optical and acoustic methods to address challenges in non-invasive diagnostic and medical imaging.1. Medical Device Development: Designed and built imaging systems for biomedical applications, integrating high-precision optical components and ensuring compliance with medical device standards.2. Optical and Prototype Design: Utilized ZEMAX and CAD software for optical and mechanical system design, developing prototypes and ensuring precise alignment for optimal system functionality and performance.3. Image Analysis : Developed advanced signal processing algorithms in MATLAB and Python, significantly improving the quality of optical signals and imaging outputs, with published results in Science Advances.4. Machine Learning: Managed large-scale imaging datasets and utilized machine learning techniques to optimize system performance and enhance diagnostic accuracy.5. Clinical Support: Provided imaging (Thermal, Optical, and Micro-CT) and data analysis for a clinical study exploring dental enamel anomalies as potential biomarkers of childhood adversity.6. Preclinical Research: Conducted wet lab research and animal handling to support preclinical imaging experiments and validate biomedical imaging systems.

Toronto, Ontario, Canada

Afimacheck Inc. is a spin-off startup from York University focused on developing a drug detection device for identifying substances in oral fluid. The company aims to provide accurate, efficient solutions for substance detection to support health and safety initiatives.1. Drug Detection Device Development: Led the design, assembly, and troubleshooting of a drug screening device for detecting substances in oral fluid.2. Prototyping and Testing: Managed the prototype assembly, ensuring the alignment of optical components and the seamless integration of hardware and software.3. Regulatory Compliance: Ensured alignment with Drugs and Driving Committee (DDC) standards under The Canadian Society of Forensic Science.

Ontario, Canada

Hybrid Biomedical Optics Laboratory, at York University is a research lab focused on translating advanced optics-based imaging technologies into clinically viable devices, pioneering optical imaging and sensing techniques for applications in disease diagnosis and monitoring. 1. Medical Device Development: Led the design and development of a medical device for detecting and quantifying human antibodies in COVID-19 patients’ blood, delivering accurate results within the clinically relevant range.2. Prototyping and Testing: Applied rapid prototyping, testing, and analysis to assess the feasibility of the device, utilizing both simulated solutions and real COVID patient specimens to evaluate performance and ensure clinical accuracy.3. Cross-functional Collaboration: Worked with engineering and clinical teams to ensure FDA compliance.4. Sample Preparation: Prepared routine media, solutions, and reagents for various experimental studies, maintaining high standards of quality control and reproducibility.

Richmond Hill, Ontario, Canada

PharmaGrand is a pharmaceutical company focused on developing innovative medical devices for drug screening and biomarker detection.1. Clinical Support: Assisted in eye exams as a Certified Ophthalmic Assistant, performing diagnostic tests and imaging.2. Data Analysis: Analyzed hospital datasets to study ocular parameters and explore vision-based diagnostic tools.3. Team Collaboration: Worked with imaging scientists, ophthalmologists, and statisticians to optimize ocular image datasets.

Waterloo, Ontario, Canada

Nanocent is a supplier of advanced nanomaterials for the electronic materials industry. Project Managment: Managed multiple projects in a start-up, including IP filings, product development, and incubator activities. Prioritized tasks, coordinated cross-functional teams, and ensured timely project completion.

Chicago, Illinois, Usa

Biomedical Optics and Ophthalmic Imaging Laboratory, Lions of Illinois Eye Research Institute, University of Illinois Chicago. The research lab focuses on advancing imaging technologies for retinal studies, disease diagnosis, and treatment evaluation, specializing in ultra-wide field fundus photography, functional OCT, and AI-based retinal image analysis.1. Device Innovation: Developed a wide-angle fundus imaging device to study infant retinopathy, contributing to cuttingedge device innovation and successfully securing a grant to support the project.2. Experimentation: Advanced functional retinal imaging with high-resolution ophthalmic instruments.3. Image Analysis: Applied image processing and machine learning for accurate pre-clinical data interpretation.4. Biomarker Research: Identified retinal biomarkers using OCT angiography and machine learning for disease classification.

Waterloo, Ontario, Canada

Taught geometrical, physical, visual, and ophthalmic optics to internationally trained optometrists and ophthalmologists as part of the International Optometric Bridging Program (IOBP).1. Developed and delivered comprehensive lecture materials, assignments, and exams tailored to prepare students for optometry licensing in Canada.2. Provided individual mentoring to address specific learning gaps and ensure a thorough understanding of complex optical concepts.3. Designed practical learning activities to connect theoretical optics with real-world clinical applications.4. Evaluated student performance through assessments and provided creative feedback to improve their knowledge and skills.5. Collaborated with program coordinators to align course content with IOBP requirements.

Waterloo, Ontario, Canada

School of Optometry and Vision Science, University of Waterloo, a leading institution in vision science and optometry education, renowned for cutting-edge research in ocular health and optical technologies.1. Developed optical systems: Designed and calibrated wavefront sensors to measure refractive errors and optical aberrations in the human eye.2. Experiment Design: Designed experiments to investigate ocular imperfections including refractive errors, and aphakia, evaluating the efficacy of spectacle corrections and intraocular lenses (IOLs) for vision restoration3. Optical Quality Assessments: Calculated PSF, MTF, and Strehl ratio to evaluate retinal image quality and the optical performance of ophthalmic devices.4. Visual acuity analysis: Analyzed factors impacting visual acuity in clinical studies and product development, providing insights into optimizing optical devices for improved vision outcomes.5. Algorithm Development: Improved image processing, signal analysis, and noise reduction for enhanced device performance.

Phd In Vision Science, Optometry And Vision Science - Ophthalmic Imaging And Image Analysis

Activities and Societies: Biomedical research

Master'S Degree, Optometry And Vision Science- Optics And Imaging

Activities and Societies: Human vision research activities

Maser'S Degree, Physics

Bachelor'S Degree, Physics