Damoder Reddy Motati Email & Phone Number

South San Francisco, Ca, Us

La Jolla, Ca, Us

Having a knowledge of medicinal chemistry and drug discovery principles, involved in creating optimization strategies for improving lead series potency, selectivity, physiochemical properties, in vitro ADME, and PK by coupling multivariant SAR analysis with hypothesis-driven medicinal chemistry design principlesPlaying a key role in design and synthesis of novel synthetic routes for the target molecules in progressing projects through the lead optimization phase to ensure the delivery of small molecules with scientific excellence, efficiency, and speed Managing lab and experience in mentoring lab-based chemists

Atlanta, Ga, Us

Involved in the design, synthesis, and SAR analysis of small molecule antagonists for EP2 receptor targeting neuroinflammation to treat CNS disorders. Developing facial synthetic routes to the key intermediates for the synthesis of EP2 antagonists and other small molecules. Developing the procedure for the PET-ligand synthesis (18F) for imaging and study of EP2 receptor. Preparation of manuscripts and studying the solubility and other properties of small molecules. Learning TR-FRET assay, solubility studies (nephelometry), and other techniques.

Jackson, Tn, Us

Proficient in synthetic organic and medicinal chemistry and focused on C-H functionalization, photocatalysis, cascade reactions, and application in the total synthesis of natural products/key intermediates. Design and synthesis of the small molecules to selectively inhibit the NOX4 enzyme to treat cardiovascular disease and pulmonary fibrosis. Large-scale chemical synthesis of NPs and applications. Developing novel routes to make key intermediates and drug candidates in eco-friendly and inexpensive routes. Monitored students and trained laboratory skills. Taught Pharm D curriculum: ADME, stereochemistry, the chemical basis of drug action, and medicinal chemistry basics to pharm D students. Published several papers including Chemical Science, Organic Letters, J. Org Chem. J. Nat. Prod. , and reviewed over 100 manuscripts from various international journals.

Jackson, Tn, Us

Albany, Ny, Us

Involved in the research and development, process chemistry of bulk drug technologies,Intensively utilized HPLC, LCMS, GCMS and NMR instruments and techniques in R&D analysis. handled Milligram to Kilogram reactions, expertized in handling 20-Liter rotary evaporators and up to 72-Liter reactors.