Damoder Reddy Motati

Damoder Reddy Motati Email and Phone Number

Principal Scientist (Medicinal Chemistry) at Nine Square Therapeutics @ Nine Square Therapeutics
Damoder Reddy Motati's Location
United States, United States
Damoder Reddy Motati's Contact Details

Damoder Reddy Motati work email

Damoder Reddy Motati personal email

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About Damoder Reddy Motati

Experienced in synthetic organic/medicinal chemistry in the quest of discovering innovative therapies. Expert in the field of organic synthesis and have hands-on experience with a wide range of modern synthetic transformations. I have demonstrated an ability to design new synthetic targets independently and, in a hypothesis, -driven manner based on emerging SAR data. Comprehensive understanding of medicinal chemistry, ADME, and working knowledge of biology in drug discovery projects. Experience in mentoring and managing both lab-based chemists and external CRO chemistry resources, ensuring productivity and efficiency. Demonstrated record of productivity in organic or medicinal chemistry research as evidenced by publications and patents. Published over 30 peer-reviewed articles with an average impact factor of 5 (overall impact factor ~150) and cited over 1000 times as per google scholar with the H index of 19. Excellent scientific problem-solving skills and a track record of bringing forward successful innovative solutions. Independent, creative target design and high level of synthetic productivity applying modern synthetic methods. In-depth knowledge and hands-on experience in synthesis, purification, and characterization of novel compounds. Experienced in optimization strategies for improving lead series potency, selectivity, physicochemical properties, in vitro ADME, and PK by coupling multivariant SAR analysis with hypothesis-driven medicinal chemistry design principles.Design and execution of greener and economic synthetic strategies for organic synthesis, and application of these methods to make new molecules of therapeutic interest.Experienced in the multi-step asymmetric total synthesis of bioactive natural products, kay intermediates, and drug-like molecules.Diligent in maintaining immaculate records of my research work and working in accordance with safety regulations. In-depth knowledge of ChemDraw®, SciFinder®, Reaxys, MestreNova®, Endnote®, and general software, etc.

Damoder Reddy Motati's Current Company Details
Nine Square Therapeutics

Nine Square Therapeutics

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Principal Scientist (Medicinal Chemistry) at Nine Square Therapeutics
Damoder Reddy Motati Work Experience Details
  • Nine Square Therapeutics
    Principal Scientist
    Nine Square Therapeutics Nov 2022 - Present
    South San Francisco, Ca, Us
  • Activx Biosciences
    Senior Research Scientist
    Activx Biosciences Feb 2021 - Sep 2022
    La Jolla, Ca, Us
    Having a knowledge of medicinal chemistry and drug discovery principles, involved in creating optimization strategies for improving lead series potency, selectivity, physiochemical properties, in vitro ADME, and PK by coupling multivariant SAR analysis with hypothesis-driven medicinal chemistry design principlesPlaying a key role in design and synthesis of novel synthetic routes for the target molecules in progressing projects through the lead optimization phase to ensure the delivery of small molecules with scientific excellence, efficiency, and speed Managing lab and experience in mentoring lab-based chemists
  • Emory University School Of Medicine
    Scientist
    Emory University School Of Medicine Feb 2019 - Jan 2021
    Atlanta, Ga, Us
    Involved in the design, synthesis, and SAR analysis of small molecule antagonists for EP2 receptor targeting neuroinflammation to treat CNS disorders. Developing facial synthetic routes to the key intermediates for the synthesis of EP2 antagonists and other small molecules. Developing the procedure for the PET-ligand synthesis (18F) for imaging and study of EP2 receptor. Preparation of manuscripts and studying the solubility and other properties of small molecules. Learning TR-FRET assay, solubility studies (nephelometry), and other techniques.
  • Union University
    Research Scientist
    Union University May 2018 - Jan 2019
    Jackson, Tn, Us
    Proficient in synthetic organic and medicinal chemistry and focused on C-H functionalization, photocatalysis, cascade reactions, and application in the total synthesis of natural products/key intermediates. Design and synthesis of the small molecules to selectively inhibit the NOX4 enzyme to treat cardiovascular disease and pulmonary fibrosis. Large-scale chemical synthesis of NPs and applications. Developing novel routes to make key intermediates and drug candidates in eco-friendly and inexpensive routes. Monitored students and trained laboratory skills. Taught Pharm D curriculum: ADME, stereochemistry, the chemical basis of drug action, and medicinal chemistry basics to pharm D students. Published several papers including Chemical Science, Organic Letters, J. Org Chem. J. Nat. Prod. , and reviewed over 100 manuscripts from various international journals.
  • Union University
    Postdoctoral Research Associate
    Union University May 2014 - Apr 2018
    Jackson, Tn, Us
  • Amri
    Research Scientist Trainee
    Amri May 2007 - Apr 2008
    Albany, Ny, Us
    Involved in the research and development, process chemistry of bulk drug technologies,Intensively utilized HPLC, LCMS, GCMS and NMR instruments and techniques in R&D analysis. handled Milligram to Kilogram reactions, expertized in handling 20-Liter rotary evaporators and up to 72-Liter reactors.

Damoder Reddy Motati Education Details

  • Indian Institute Of Chemical Technology
    Indian Institute Of Chemical Technology
    Organic Chemistry

Frequently Asked Questions about Damoder Reddy Motati

What company does Damoder Reddy Motati work for?

Damoder Reddy Motati works for Nine Square Therapeutics

What is Damoder Reddy Motati's role at the current company?

Damoder Reddy Motati's current role is Principal Scientist (Medicinal Chemistry) at Nine Square Therapeutics.

What is Damoder Reddy Motati's email address?

Damoder Reddy Motati's email address is da****@****ivx.com

What schools did Damoder Reddy Motati attend?

Damoder Reddy Motati attended Indian Institute Of Chemical Technology.

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