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An accomplished and experienced leader of both computational and wet lab groups in preclinical and clinical studies across a range of therapeutic areas. Proven success managing teams of large sizes and compositions, and interrogating large, disparate datasets with advanced analytics and machine learning for target discovery, clinical development and precision medicine. Currently heading immunology computational biology at AbbVie, a group of 10+ computational biologists supporting all stages of the immunology discovery, development and clinical pipelines. Previously managed the multi-omics sequencing group at Merck that specializes in single cell sequencing and tissue-based spatial transcriptomic profiling, supporting all therapeutic areas including oncology, immunology, neuroscience and infectious disease and vaccine.
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Executive DirectorBristol Myers SquibbCambridge, Ma, Us
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Director Ii, Head Of Immunology Computational BiologyAbbvie Apr 2022 - PresentNorth Chicago, Illinois, UsLeading the immunology computational biology group (10+ scientists) to support the immunology discovery, development and clinical trials. Enable the end-to-end pipeline advancement, biomarker development and translational medicine with multi-omics and analytics, and drive key business decisions with big data and machine learning. -
Principal Scientist/Director, Head Of The Multiomics Sequencing GroupMerck Nov 2019 - Apr 2022Rahway, New Jersey, UsLead the multi-omic single cell sequencing and spatial transcriptomics effort at Merck, supporting discovery, biomarker development and digital pathology in all therapeutic areas. -
Associate Principal Scientist, Informatics And Analytics, Genetics And Pharmacogenomics (Gpgx)Merck May 2018 - Nov 2019Rahway, New Jersey, UsDesign experiments and perform analysis of high throughout sequencing data for infectious diseases and vaccines and immunology programs. The types of projects include single cell sequencing, RNA sequencing, immune repertoire profiling, de novo genome assembly with PacBio sequencing and Hi-C, etc.
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Senior Scientist, Informatics And Analytics, Computational Genomics And GeneticsMerck Jan 2016 - May 2018Rahway, New Jersey, UsMy main responsibility is developing and implementing bioinformatic and statistical pipelines and methods for translational medicine research. I'm also involved in projects that use machine learning to guide business decisions.
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Postdoctoral Research FellowUniversity Of California, Santa Cruz Jan 2013 - Dec 2015Santa Cruz, Ca, UsPI: Beth Shapiro, Richard Edward GreenMy postdoctoral research is about ancient DNA -- obtain genomic information from ancient animal remains using next generation sequencing, design custom bioinformatic pipelines to differentiate real ancient DNA sequences from contaminants, and develop sophisticated statistical methods to infer phenotypic changes, population dynamics, targets of selection and climate change. My main projects are a) finding targets of domestication by studying whole genomes of 47k and 13k years old wild horses, b) exploring the population dynamics of mammoths through time, c) evaluating how Pleistocene climate changes affected local horse and bison populations, and d) testing if getting dinosaur genome is mission impossible. -
Graduate Student InstructorUniversity Of Michigan Sep 2006 - Dec 2012Ann Arbor, Michigan, Us -
Graduate Research AssistantUniversity Of Michigan Jan 2009 - Dec 2009Ann Arbor, Michigan, Us
Dan Chang Skills
Dan Chang Education Details
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University Of MichiganEcology And Evolutionary Biology -
University Of MichiganStatistics
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University Of MichiganEcology And Evolutionary Biology
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Ocean University Of ChinaBiological Science
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Ocean University Of ChinaComputer Science
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Cornell UniversityMerck Women’S Leadership Program/Gender Bias & Negotiating Strategies/Navigating Power Relationships
Frequently Asked Questions about Dan Chang
What company does Dan Chang work for?
Dan Chang works for Bristol Myers Squibb
What is Dan Chang's role at the current company?
Dan Chang's current role is Executive Director.
What is Dan Chang's email address?
Dan Chang's email address is da****@****rck.com
What is Dan Chang's direct phone number?
Dan Chang's direct phone number is +190874*****
What schools did Dan Chang attend?
Dan Chang attended University Of Michigan, University Of Michigan, University Of Michigan, Ocean University Of China, Ocean University Of China, Cornell University.
What skills is Dan Chang known for?
Dan Chang has skills like Statistics, Bioinformatics, Molecular Biology, R, Pcr, Lifesciences, Genomics, Matlab, Evolutionary Genetics, Molecular Ecology, Biostatistics, Marine Biology.
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