Danai Topouza Email & Phone Number

Toronto, On, Ca

Toronto, On, Ca

Montreal, Quebec, Canada

Montreal, Quebec, Canada

- Trained in the analysis of single-cell RNA-seq, ChIP-seq, ATAC-seq, and Paired-Tag datasets- Created reproducible analysis pipelines using R and R markdown in a Unix-based HPC environment- Characterized the tumor immune microenvironment of pediatric brain tumors at single-cell resolution- Investigated the epigenetic regulation of isoforms in cell lineages of the developing brain

Kingston, Ontario

- Designed analysis workflows for high-throughput RNA- and microRNA-sequencing data using R and Unix programming in an HPC environment- Directed and performed DNA methylation analyses in circadian rhythm genes, leading to three publications- Led genome-wide and phenome-wide association studies (GWAS, PheWAS) on asthma risk variants in the longitudinal, high-dimensional CHILD Study Cohort dataset- Contributed to literature review and statistical analyses for grant applications- Maintained lab communications server and website

Ontario, Canada

Academic mentorship- Mentored 4 Masters students in biostatistics and biomedical informatics- Provided training in bioinformatics methodologies and scientific writingBMIF 803: Biomedical Data Mining and Applications (Summer 2020)- Guest lecturer: Introduction to R, Unix, and high-performance computing; introduction to gene co-expression network analysis methods- Designed and delivered lectures, edited and graded assignmentsBMED 370: Genetics and Genomics (Winter and Fall 2018)- Assisted with student questions and graded assignmentsBIOL 102: Introductory Biology of Cells (Fall 2017)- Delivered tutorials on introductory biology and supervised wet lab componentCISC 101: Elements of Computer Science (Fall 2015, Fall 2016)- Supervised hands-on learning tutorials in Python and MATLAB programming- Delivered guest lecture on code testing and exception handling

Ontario, Canada

- Identified gene networks and germline variants involved in chemotherapy response, leading to two publications- Designed RNA-seq and Whole Exome Sequencing data processing and analysis workflows in R in an HPC environment- Performed transcriptome, microRNA, expression quantitative trait locus (eQTL) and genomic variant analysis - Performed gene network analyses and patient survival analyses (Cox regression)- Curated, performed quality control, and integrated several datasets from The Cancer Genome Atlas

Master Of Science - Ms, Computational Biology

Bachelor Of Science - Bs, Molecular Biology

BScH in Biology (Major) and Computer Science (Minor)