Pharmaceutical Consultant
Daniel P Fitzgerald Consulting
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Daniel Fitzgerald Email & Phone Number
Pharmaceutical Consultant
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Daniel P Fitzgerald Consulting
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Current company
Daniel P Fitzgerald Consulting
Role
Pharmaceutical Consultant
Location
Washington Dc-Baltimore Area, United States
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Daniel Fitzgerald is listed as Pharmaceutical Consultant at Daniel P Fitzgerald Consulting, based in Washington Dc-Baltimore Area, United States. AeroLeads shows a matched LinkedIn profile for Daniel Fitzgerald.
Daniel Fitzgerald previously worked as Director, Preclinical Research at Nextcure, Inc. and Associate Director, Discovery Research at Nextcure, Inc.. Daniel Fitzgerald holds Phd, Biological And Biomedical Sciences from Harvard Medical School.
Profile bio
About Daniel Fitzgerald
A biologist with over 20 years’ experience in biomedical research including 12+ years’ experience in preclinical drug development. Liaison for cross-functional efforts between Discovery, Translational Research laboratory teams, Assay Development, Clinical, Biomarkers, Drug Development, Manufacturing, Business Development, and external partners to ensure strategic alignment. Breadth of technical experience with publications in the fields of molecular and developmental biology, genetics, neurobiology, cancer, and immunology. Leadership experience directing multiple stages of drug development from inception to clinical trial initiation. Responsibilities ranging from high-throughput screening, early target validation and drug discovery, to IND-enabling efficacy, safety, and translational studies. Passionate about coaching and empowering scientific colleagues. Experience working with both small molecule and biologic drug candidates. Recent focus on oncology, immune oncology, and targeted (antibody-drug conjugate) cancer therapeutics.
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Daniel Fitzgerald's current company
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Daniel P Fitzgerald Consulting
11 roles · 34 years
Daniel Fitzgerald work experience
A career timeline built from the work history available for this profile.
Director, Preclinical Research
Research Fields: Immune oncology and targeted cancer therapeutics. Led preclinical / translational teams for 3 pipeline assets.• Preclinical lead for an antibody drug conjugate (ADC) program (LNCB74). Strategic partnership with LigoChem Biosciences (LCB) to generate and collate preclinical data package for IND filing.• Translational / preclinical director for an immune oncology program (NC318) targeting tumor-associated macrophages.• Translational / preclinical director for a Phase 1 candidate therapeutic targeting immunomodulatory protein B7-H4 (NC762) with a mAb designed to engage natural killer (NK) cells.
Jan 2022 - Mar 2024
Associate Director, Discovery Research
• Led preclinical research efforts for a candidate therapeutic (NC318).• Supported research efforts for second research program (NC762). • Created and managed a team to identify and validate functional binding partners for multiple pipeline assets.• Managed high throughput functional screens to identify novel immunomodulatory targets.• Oversaw the molecular biology group for Discovery Research.
Feb 2020 - Jan 2022
Manager, Discovery Research
•Develop and optimize functional assays for the identification of novel immunomodulatory targets (http://www.nextcure.com/discovery/)•Maintain high-throughput platforms (ZE5/Ascent robotic flow cytometers, Opera Phenix HCS platform, Biomek-i7 Liquid Handlers)•Analyzed and assimilated datasets composed of up to 36,000 data points from >150 screens for downstream bioinformatic analyses•Collaborate in a strategic partnership with Eli Lilly
Mar 2019 - Feb 2020
Scientist Iii
•Developed experimental strategies to screen human gene libraries and identify novel drug targets.•Designed and implemented High Content Screening (HCS) methods.•Designed and implemented high throughout flow cytometry assays.•Analyzed and compiled datasets from gene library screens.•Identified, selected, and validated novel drug targets.
Feb 2017 - Feb 2019
Scientist, Drug Evaluation
Research Fields: Preclinical oncology and cancer immunology.• Developed high throughput small molecule screens.• Measured small molecule pharmacokinetics using mouse models.• Conducted in vitro and in vivo experiments to measure anti-tumor activity of candidate small molecule therapeutics.• Performed post-mortem pathology on tumors and mouse tissues.
Oct 2011 - Dec 2016
Postdoctoral Fellow
Advisor: Patricia Steeg, Ph.D., Laboratory of Molecular Pharmacology. Research Fields: Breast cancer and brain metastasis. Evaluate anti-tumor efficacy of brain-permeable candidate therapeutics.
2006 - Sep 2011
Postdoctoral Fellow
Neural development and brain stem cell research. (Advisors: Dr. Perry Bartlett/Dr. Helen Cooper)
2003 - 2005
~2 yrs
Teaching Fellow
Undergraduate Biology/Genetics (Course Chairs: Dr. Dan Hartl/Dr. William Gelbart)
2001 - 2002
~1 yr
2001 - 2001
Phd Graduate Student
Developmental biology, gene expression, and transriptional regulation research. (Advisor: Dr. Welcome Bender)Recommendation from Dr. Bender (not a LinkedIn member): Dan Fitzgerald was a PhD student in my lab at Harvard Med School from 1995 to 2001. He developed several techniques to probe the structure of regions of a chromosome in the fruit fly, a widely used model organism. He demonstrated that genes which are turned off, by a mechanism called Polycomb repression, are physically inaccessible to proteins in the nucleus. It took years of persistence to set up the assays, and skillful genetic and molecular work to generate the results. The major publication from his thesis (Fitzgerald and Bender (2001) Mol. Cell Biol. 21:6585-6597) is still the best evidence for chromosome compaction by Polycomb repression. Dan did it all on his own, and by the end of his time, he was more familiar than I with the relevant literature, and more thoughtful about experimental details. He was among the very best students in our graduate program. Please phone (617-432-1906), if I could help with additional comments.Welcome BenderHarold T. White professor of Biological Chemistry
1993 - 2001
~8 yrs
4 education records
Daniel Fitzgerald education
Phd, Biological And Biomedical Sciences
Harvard Medical School
Phd, Biological Chemistry And Molecular Pharmacology
Harvard University
B.S., Biotechnology
Rutgers University
High School
Pitman High School
FAQ
Frequently asked questions about Daniel Fitzgerald
Quick answers generated from the profile data available on this page.
What company does Daniel Fitzgerald work for?
Daniel Fitzgerald works for Daniel P Fitzgerald Consulting.
What is Daniel Fitzgerald's role at Daniel P Fitzgerald Consulting?
Daniel Fitzgerald is listed as Pharmaceutical Consultant at Daniel P Fitzgerald Consulting.
Where is Daniel Fitzgerald based?
Daniel Fitzgerald is based in Washington Dc-Baltimore Area, United States while working with Daniel P Fitzgerald Consulting.
What companies has Daniel Fitzgerald worked for?
Daniel Fitzgerald has worked for Daniel P Fitzgerald Consulting, Nextcure, Inc., Otsuka Maryland Medicinal Laboratories, Otsuka Pharmaceuticals, National Cancer Institute, Nih, and Queensland Brain Institute, University Of Queensland, Australia.
How can I contact Daniel Fitzgerald?
You can use AeroLeads to view verified contact signals for Daniel Fitzgerald at Daniel P Fitzgerald Consulting, including work email, phone, and LinkedIn data when available.
What schools did Daniel Fitzgerald attend?
Daniel Fitzgerald holds Phd, Biological And Biomedical Sciences from Harvard Medical School.
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