Daniel Rosebrock Email & Phone Number

Hamburg, Germany

Berlin Area, Germany

• Lead comparative analysis to measure regional and cell type heterogeneity in cerebral organoids produced under variety of derivation protocols using scRNA-Seq, RNA-Seq & immunostainings• Develop pipeline to multiplex scRNA-Seq datasets across multiple cell lines and remove empty droplets containing ambient RNA signal• Measure transcriptional dynamics along neuronal differentiation trajectories with MCMC approach and build time-dependent gene regulatory networks• Supervise Bachelor… Show more • Lead comparative analysis to measure regional and cell type heterogeneity in cerebral organoids produced under variety of derivation protocols using scRNA-Seq, RNA-Seq & immunostainings• Develop pipeline to multiplex scRNA-Seq datasets across multiple cell lines and remove empty droplets containing ambient RNA signal• Measure transcriptional dynamics along neuronal differentiation trajectories with MCMC approach and build time-dependent gene regulatory networks• Supervise Bachelor student 6-week internship – scRNA-Seq cluster-based cell type annotation Show less

Cambridge, Ma

• Applied existing and novel computational algorithms to cancer data sets of WES, WGS, and RNA-Seq Next-Generation Sequencing data in large-scale collaborations• Developed Bayesian approach to identify subclones and model cancer evolution and progression based on somatic mutations and copy number events (PhylogicNDT)• Migrated computational pipelines to cloud-based computing platforms (Amazon Web Services and Google Cloud Platform) using Docker engine environment

Master Of Science (M.Sc.), Mathematics

Bachelor Of Arts (B.A.), Mathematics And German