Versatile statistician with an extended experience in clinical (according to FDA and EMA requirement) , preclinical and drug-discovery research, in addition to vast teaching experience in academia and industry. Current position: Senior Director of Clinical Research and Biostatistics in Quark Pharmaceuticals LTD.Clinical experienceLed the clinical development strategy from IND submission to NDA - phase I II & III. Highly involved in the correspondence with FDA on all statistics related issues in clinical development plans, which are all assembled into the SAP (Statistical Analysis Plan) manuscript. Acquired a vast experience in the design of complex innovative clinical trials with cutting edge statistical methodologies, such as sample size re-estimation for complex study endpoints, adaptive and sequential design. Assimilation of statistical methodologies into the working environment, including the use of “esitmands” language in the organization day to day work. Experience in implementation of rigorous statistical methods for the handling and analyses of clinical trial with missing data.Pre-clinicalLed the experiments design, monitoring, analysis and documentation of in-silico, in-vitro and in-vivo studies.Developed an In-vivo data base that handles all the company in-vivo studies design, stores all data obtained in the experiment, including general animal information, and allows querying and monitoring the data in a simple manner. Developed algorithms for analysis: High-through-put screening qPCR, ELISA and Microarray studies, which were implemented in interactive databases. Management skills Led a team of senior statisticians. Coordinated and integrated different disciplines (Statistics, physicians, biologists, project managers, programmers) for clear communication across the company.Managed, recruited, and supervised contract research organizations (CROs): statistical programmers; data managers.