Daniel Doheny, Phd Email & Phone Number
@bioagilytix.com
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Who is Daniel Doheny, Phd? Overview
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Daniel Doheny, Phd is listed as MSAT Senior Scientist at Lonza, a company with 390 employees, based in Raleigh-Durham-Chapel Hill Area, United States, United States. AeroLeads shows a work email signal at bioagilytix.com and a matched LinkedIn profile for Daniel Doheny, Phd.
Daniel Doheny, Phd previously worked as Scientist I at Bioagilytix and Graduate Student Researcher at Wake Forest University Graduate School. Daniel Doheny, Phd holds Doctor Of Philosophy - Phd, Cancer Biology from Wake Forest University Graduate School.
Email format at Lonza
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AeroLeads found 1 current-domain work email signal for Daniel Doheny, Phd. Compare company email patterns before reaching out.
About Daniel Doheny, Phd
I am a recent Ph.D. graduate excited to leverage my strong research background and expertise in assay optimization and preclinical drug development to impact disease on the molecular level and help bring new diagnostics and therapies to the clinic.After studying Biochemistry at UNC Chapel Hill, I interned at The Hamner Institutes for Health Sciences where I learned the basics of cell culture and how to apply the scientific method to develop and validate cell-based in vitro assays. When The Hamner was acquired by SciMetrika and rebranded into ScitoVation, I expanded my working knowledge of assay technologies to include colorimetric and fluorescent plate reader assays, ELISAs, flow cytometry, and high-content imaging. I worked on a multidisciplinary team to develop high-throughput assays to model tissue responses to estrogenic compounds and those thought to cause abnormal adipocyte growth to better predict human responses and inform chemical risk assessment. As my skill set and role within the company grew, I found myself asking technical and conceptual questions that I could not answer with my current knowledge, but knew a career in research was right for me. To continue to advance, I started my graduate education at the Wake Forest Graduate School of Arts & Sciences in August 2017.For my Master’s degree, I joined Dr. Hui-Wen Lo’s lab to identify and study inhibitors of the oncogenic protein tGLI1 which promotes glioblastoma and breast cancer tumor progression and metastasis to the brain by potentiating the cancer stem cell population. Using a cell-based compound screen, we found that ketoconazole, an FDA-approved antifungal, selectively killed tGLI1-expressing breast cancer cells without affecting normal cell populations in the brain and breast microenvironments. This preclinical work laid the foundation for an ongoing early Phase I clinical trial to determine if ketoconazole can modulate tGLI1 signaling in brain biospecimens. Excited to continue learning and grow into an independent scientist, I graduated with my Master’s degree and transitioned into the Ph.D. program under Dr. Lo’s continued mentorship.My dissertation research involved creating and characterizing novel small molecule tGLI1 inhibitors to treat breast cancer brain metastases and recurrent gliomas. To date, I have characterized 4 novel small molecule tGLI1 inhibitors, 2 of which have commercial viability.Want to connect? Feel free to reach out here on LinkedIn.
Listed skills include Cell Culture, Transfection, High Content Imaging, Assay Development, and 29 others.
Daniel Doheny, Phd's current company
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Daniel Doheny, Phd work experience
A career timeline built from the work history available for this profile.
Scientist I
Current- As a Scientist I at BioAgilytix, I serve as the lead scientist on multiple projects involving method development, transfer, qualification, and validation of pharmacokinetic, anti-drug antibody, neutralizing antibody.
- 98.5% plate pass rate across development, qualification, validation, and sample analysis assays performed under GLP/GCLP guidelines.
- Support the professional development of new employees as an instructor of the Lab Calculations New Employee Onboarding seminar.
- Key technical proficiencies include: Laboratory Inventory Management Software (LIMS), ZenQMS, Gen5, MesoScale Discovery (MSD), Vi-Cell, Synergy Neo2
Graduate Student Researcher
- I earned my PhD in Cancer Biology under the mentorship of Dr. Hui-Wen Lo at the Wake Forest Graduate School of Arts & Sciences. My dissertation research involved identifying and characterizing small molecule inhibitors.
- Evaluated the efficacy and mode of action of 4 novel compounds (2 with commercial viability) that inhibit a novel actionable target, upregulated in brain metastases and gliomas, leading to 7 training awards totaling.
- Implemented standardized protocols to image and analyze immunohistochemistry staining to profile tumor samples increasing throughput by 75% and reducing experimental error by at least 25%.
- Developed professional relationships with key scientists and clinical oncologists resulting in 7 peer-reviewed publications on topics including breast cancer and cancer therapeutics.
- Presented scientific data at 6 internal seminars and 3 international conferences, including the American Association for Cancer Research Annual Meeting.
- Mentored 7 trainees including junior graduate students, rotating medical students, and undergraduate students.
Scientist Ii
- As a Scientist at ScitoVation, I worked as part of a multidisciplinary team to develop and optimize high-throughput cell-based multiplex assays to redefine the paradigm of toxicity testing by reducing animal use and.
- Collaborated to develop a multiplex cell-based assay to measure tissue-specific estrogen responses leading to 1 publication and a podia presentation at the 5th Annual meeting of the American Society for Cellular and.
- Optimized an ELISA to assess xenobiotic-induced adipokine secretion featured in 2 publications.
- Mentored and trained 2 technicians on sterile cell culture and assay execution.
- Prepared quarterly reports to provide updates on completion of key deliverables.
- Managed chemical and cell line inventory.
Scientist I
- After ICSS was acquired and rebranded into ScitoVation, a wholly owned subsidiary of SciMetrika, I was hired as a Scientist and expanded on my previous work at The Hamner.
- Evaluated several assay technologies to measure estrogen-induced uterine cell growth culminating in 1 publication.
- Streamlined chemical inventory and safety documentation management which reduced waste by 50%.
Research Intern
- I spent one year as an intern at the Institute for Chemical Safety Sciences (ICSS) of The Hamner Institutes for Health Sciences, a not-for-profit brain trust that advanced new human-systems biology approaches for.
- Presented 2 scientific posters describing the acquired data at The Hamner Technology Showcase Series.
Building Operations Student Supervisor
- Organized employees to prepare gym facilities for use by student teams and organizations.
- Served as an information resource for employees and patrons on gym policies.
- Supervised groups of 6+ employees during my shift.
- Worked 12 hours per week while attending school full time.
Operations Ambassador
- Distributed sports equipment to gym members.
- Served as a source of information on gym policies and planned events for gym patrons.
- Provided superb customer service.
- Worked at least 6 hours per week while attending school full time.
Colleagues at Lonza
Other employees you can reach at bioagilytix.com. View company contacts for 390 employees →
Lauren Scheetz
Colleague at Lonza
Southport, North Carolina, United States, United States
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NA
Noel Antonio Sanchez Perdomo
Colleague at Lonza
Bogota, D.C., Capital District, Colombia, Colombia
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Samantha Loera
Colleague at Lonza
San Diego, California, United States, United States
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JA
Javier Alarcon
Colleague at Lonza
Durham, North Carolina, United States, United States
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CM
Courtney Metz
Colleague at Lonza
Providence, Rhode Island, United States, United States
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AZ
Angela Ziegler
Colleague at Lonza
Cocoa, Florida, United States, United States
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KH
Katie Hoppe
Colleague at Lonza
United States, United States
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JH
Jessica Hou
Colleague at Lonza
Beijing, China, China
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KP
Khristopher Purvis
Colleague at Lonza
Durham, North Carolina, United States, United States
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JK
Johnna King
Colleague at Lonza
Wake Forest, North Carolina, United States, United States
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Daniel Doheny, Phd education
Doctor Of Philosophy - Phd, Cancer Biology
Master Of Science - Ms, Biomedical Sciences
Bachelor Of Science - Bs, Biochemistry
Education record
Frequently asked questions about Daniel Doheny, Phd
Quick answers generated from the profile data available on this page.
What company does Daniel Doheny, Phd work for?
Daniel Doheny, Phd works for Lonza.
What is Daniel Doheny, Phd's role at Lonza?
Daniel Doheny, Phd is listed as MSAT Senior Scientist at Lonza.
What is Daniel Doheny, Phd's email address?
AeroLeads has found 1 work email signal at @bioagilytix.com for Daniel Doheny, Phd at Lonza.
Where is Daniel Doheny, Phd based?
Daniel Doheny, Phd is based in Raleigh-Durham-Chapel Hill Area, United States, United States while working with Lonza.
What companies has Daniel Doheny, Phd worked for?
Daniel Doheny, Phd has worked for Lonza, Bioagilytix, Wake Forest University Graduate School, Scitovation, and The Hamner Institutes For Health Sciences.
Who are Daniel Doheny, Phd's colleagues at Lonza?
Daniel Doheny, Phd's colleagues at Lonza include Lauren Scheetz, Noel Antonio Sanchez Perdomo, Samantha Loera, Javier Alarcon, and Courtney Metz.
How can I contact Daniel Doheny, Phd?
You can use AeroLeads to view verified contact signals for Daniel Doheny, Phd at Lonza, including work email, phone, and LinkedIn data when available.
What schools did Daniel Doheny, Phd attend?
Daniel Doheny, Phd holds Doctor Of Philosophy - Phd, Cancer Biology from Wake Forest University Graduate School.
What skills is Daniel Doheny, Phd known for?
Daniel Doheny, Phd is listed with skills including Cell Culture, Transfection, High Content Imaging, Assay Development, Agarose Gel Electrophoresis, Research, Bacterial Transformation, and Aseptic Technique.
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