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As the Director of Scientific Operations at Ionpath, I lead a team of laboratory scientists, in collaboration with bioinformaticians, to provide imaging and bioinformatic services using the Multiplex Ion Beam Imaging (MIBI) platform. I have over four years of experience in managing complex and multidisciplinary scientific projects, involving multiple stakeholders, sites, and goals.My expertise in program management stems from my previous role as the Scientific Program Manager for the HOPE Martin Delaney Collaboratory for HIV Cure Research, a multimillion-dollar NIH funded HIV cure collaboratory, where I tracked and monitored progress towards milestones, goals, and deliverables, established collaboratory-wide budgets, and instituted effective methods of communication. I also have a strong scientific background in virology and genetics, with a Ph.D. from Yale University and several publications in peer-reviewed journals, focusing on the epigenetic regulation of cellular and viral genes in varying viral disease states. My mission is to foster an open and collaborative environment where members from different disciplines can share their unique expertise and deliver high-quality and innovative scientific services to customers.
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Director Of Scientific OperationsTahoe TherapeuticsCalifornia, United States -
Director Of Scientific OperationsIonpath Jul 2023 - PresentMenlo Park, California, Us -
Scientific Program ManagerIonpath Jul 2022 - Jul 2023Menlo Park, California, Us•Scientific Program Manager for the SPS department, which provides imaging and bioinformatic services using the Multiplex Ion Beam Imaging (MIBI) platform.•Responsible for the tracking and prioritizing of all SPS projects involving a cross-functional team of laboratory scientists, pathologists and bioinformaticians.•Function as the primary point of contact for service customers and responsible for maintaining customer satisfaction throughout their project. •Determine delivery timeline and resourcing for new projects and ensure on time delivery to customers.•Ensure efficient communication of resourcing, timelines and project risks to all internal stakeholders.•Lead and organize team stand-up, process and strategy meetings and maintain departmental meeting minutes.•Responsible for developing and communicating the SPS financial forecast to the finance department, and communicating project completion for billing.•Updated existing project tracking, information storage, and resource projection methods using Jira, Confluence, Google Suite and Gantt charting.•Lead the development of process documentation for SPS for GxP certification, including communicating with external contractors. -
Scientific Program LeadGladstone Institutes Aug 2021 - Jul 2022San Francisco, California, Us• Program Manager for the HOPE Martin Delaney Collaboratory for HIV Cure Research, a multimillion dollar NIH funded HIV cure collaboratory.• Track and monitor progress towards milestones, goals and deliverables, including early identification of potential problems and developing solutions to maintain on timeline progress. HOPE’s goals center around drug development, novel gene editing, and targeted drug delivery methods.• Established collaboratory wide budgets and monitor spending; including reconciling areas where budgets are not in line with progress or goals.• Instituted effective methods of communication throughout the multidisciplinary team of scientists and HIV community members across the 16 sites in six countries.• Evaluate external research and notify collaboratory members of important scientific advancements and potential for collaboration.• Serve as the point of communication between HOPE scientists and community groups.• Launched and maintain the HOPE website in collaboration wih an external website design contractor.• Working with all HOPE members to insure relevant regulatory and legal requirements are established and followed.• Spearheaded the HOPE kick-off, an online two day meeting with over 100 attendees; including setting the agenda and arranging speakers across multiple time zones.• Coordinate efficient communication between the NIH Program Officer and HOPE leadership.• Onboarding, training and managing the HOPE Program Coordinator. The Program Coordinator assists in administrative tasks such as meeting planning and everyday HOPE wide communications.• Awarded the Gladstone Institute in Virology Excellence in Scientific Leadership Award. -
Postdoctoral ScholarGladstone Institutes Jan 2019 - Jul 2022San Francisco, California, Us• Oversaw the HOPE Collaboratory NIH application as the Program Manager starting in August 2020, including contacting potential collaborators, setting budgets, and organization of written materials and oral presentations needed for NIH grant submission.• Supervising and training a Research Assistant in a complex research project on regulation of HIV latency.• Studying regulation of HIV latency using next-generation sequencing methods, such as ChIP-seq, CUT&RUN, and DRIP-seq, in order to identify possible targets to prevent viral reactivation. • Implemented a new technique, DRIP-seq, at Gladstone through a partnership with a collaborator at UC-Davis.• Determining the role that RNA polymerase C-terminal domain acetylation plays in promoter proximal pausing. • Completed a project studying Hepatitis C Virus (HCV) in a novel liver organoid system using single-cell RNA sequencing. -
Phd CandidateYale University School Of Medicine Aug 2012 - Apr 2018New Haven, Ct, Us• Studied viral and cellular gene regulation during Epstein-Barr virus lytic reactivation.• Led a project using qPCR and next generation sequencing (NGS) to identify genes differentially regulated during EBV reactivation that may play a role in development of EBV associated cancers, particularly gastric carcinoma.• Discovered a new class of EBV genes that can be regulated by mutant cellular transcription factors using RT-qPCR, western blotting, ChIP, and Northern blotting.• Partnered with bioinformatic collaborators for the completion of analysis of RNAseq , DNAseq, and ChIP-seq data. -
Research AssistantYale University School Of Medicine Jul 2011 - Aug 2012New Haven, Ct, Us• Studied Hepatitis C Virus and Yellow Fever Virus replication.• Performed a high throughput small molecule screen, at the Yale Center for Molecular Medicine, to identify inhibitors of YFV replication in human cell lines. • Responsible for lab manager duties, including organizing laboratory materials, ordering common lab items, and maintaining E. coli and yeast strains for general lab research. -
Graduate Teaching FellowYale University Aug 2014 - Dec 2016New Haven, Ct, UsGraduate Teaching Fellow for five semesters. Biology 102: Cell Biology and Membrane Physiology(Fall 2014, 2015, 2016)Duties: leading weekly discussions of primary literature for approximately 20 science majors, grading homework, holding weekly volunteer office hours, holding exam review sessions, and grading exams.Biology 103: Genes and Development(Spring 2016)Duties: leading weekly discussions of primary literature for approximately 20 science majors, grading homework, holding weekly volunteer office hours, and grading exams.Molecular, Cellular and Developmental Biology 291L: Laboratory for Microbiology (Spring 2015) Duties included: assisting approximately 15 students in performing laboratory experiments in the classroom, grading lab reports, and generating all quiz material for the course. -
Student Lab CoordinatorColorado State University 2008 - 2011Fort Collins, Co, UsWorked under the direction of Drs. Patrick Brennan and Vara Vissa. I worked using PCR and DNA sequencing to identify patients infected with M. leprae (the etiologic agent causing leprosy) harboring mutations leading to drug resistance.I also tested protocols to purify LAM from M. leprae for use by collaborators in immunological studies.
Danielle Lyons Skills
Danielle Lyons Education Details
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Yale UniversityMicrobiology -
Yale UniversityMicrobiology -
Colorado State UniversityMicrobiology
Frequently Asked Questions about Danielle Lyons
What company does Danielle Lyons work for?
Danielle Lyons works for Tahoe Therapeutics
What is Danielle Lyons's role at the current company?
Danielle Lyons's current role is Director of Scientific Operations.
What is Danielle Lyons's email address?
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What is Danielle Lyons's direct phone number?
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What schools did Danielle Lyons attend?
Danielle Lyons attended Yale University, Yale University, Colorado State University.
What skills is Danielle Lyons known for?
Danielle Lyons has skills like Molecular Biology, Genetics, Qpcr, Virology, Cell Culture, Western Blotting.
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