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Experienced Research Director with a demonstrated history of working in the biotechnology industry. Manages a group of scientists that design novel antibody platforms, express and purify proteins, develop cell lines for production and perform deep dive physicochemical characterization of novel biological therapeutics. Skilled in Biotechnology, Molecular Biology, Protein Engineering, Antibody Engineering, Protein Expression, Protein Purification, liver physiology, yeast genetics transport biology and cell line development. Worked closely with biologists to design and implement in vitro, ex vivo and in vivo studies in mice and non-human primates which established potency, effectiveness, pharmacokinetics and pharmacodynamics. Designed and patented a novel Fc based immunosuppressant drug. Managed and participated in collaborations with research groups of a partnered pharmaceutical company to take that drug into humans. Designed and patented a novel Fc scaffold that greatly enhances antibody killing effector functions and is currently being tested against multiple targets in oncology and autoimmunity. Efforts with these designs lead to declarations of three separate drug candidates which were nominated to go into the clinic.
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Senior Director Of ResearchInozyme Pharma Apr 2022 - PresentBoston, Massachusetts, Us
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DirectorThe Janssen Pharmaceutical Companies Of Johnson & Johnson Oct 2020 - Mar 2022Raritan, New Jersey, Us -
Director, ResearchMomenta Pharmaceuticals Jun 2020 - Sep 2020Cambridge, Massachusetts, Us -
Associate Director Of ResearchMomenta Pharmaceuticals Feb 2018 - Jun 2020Cambridge, Massachusetts, Us
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Principal ScientistMomenta Pharmaceuticals Jan 2015 - Jan 2018Cambridge, Massachusetts, Us
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Senior ScientistMomenta Pharmaceuticals Jun 2013 - Dec 2014Cambridge, Massachusetts, Us
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Associate DirectorMomenta Pharmaceutical Nov 2018 - Jun 2020
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Principal ScientistMomenta Pharmaceutical Jan 2015 - Jan 2018
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Research Assistant ProfessorTufts University School Of Medicine, Dept. Of Cellular And Molecular Physiology Jan 1996 - Nov 2011Medford, Massachusetts, UsBackground in molecular biology, physiology, cellular biology, protein biochemistry and genetics.Proficient in use of in vivo (rodent), ex vivo (cultured cells) and yeast model systems to analyze protein function, localization and interactionsExtensive expertise in design of recombinant constructs for expression in mammalian, yeast and bacterial systems Proven talent planning and producing successful research proposals as principal investigator and in collaboration with colleaguesAbility to work as part of a team and in collaborative efforts.Aptitude for teaching, training and supervising postdoctoral fellows, technicians and graduate studentsExcellent oral and written communication skills -
Research AssociateTufts University School Of Medicine, Dept. Of Cellular And Molecular Physiology Jan 1993 - Jan 1996Medford, Massachusetts, UsPerformed research that led to identification and characterization of the yeast bile acid transporter, BAT1. Identified, cloned and characterized the BAT1 mammalian ortholog, MRP3.Obtained independent funding for research (National Institutes of Health R03 2 year award 1995)
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Research Assistant ProfessorTufts University School Of Medicine Aug 1993 - Jul 2011Boston, Ma, Us -
Research Assistant ProfessorTufts University School Of Medicine Aug 1993 - Jul 2011Boston, Ma, Us
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Research GeneticistGene Expression Center Uc Jan 1990 - Jan 1993/USDAIdentified and cloned yeast genes essential for heavy metal tolerance. Demonstrated that the HMT1 transporter sequesters heavy metal conjugates in vacuoles and that purine biosynthetic genes perform additional functions essential for heavy metal tolerance. Obtained independent funding for research (USDA 2 year competitive research award
Daniel Ortiz Skills
Daniel Ortiz Education Details
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University Of Georgia Graduate School Of Arts And SciencesMolecular -
University Of Costa RicaBiology
Frequently Asked Questions about Daniel Ortiz
What company does Daniel Ortiz work for?
Daniel Ortiz works for Inozyme Pharma
What is Daniel Ortiz's role at the current company?
Daniel Ortiz's current role is Senior Director of Research, Inozyme Pharma.
What is Daniel Ortiz's email address?
Daniel Ortiz's email address is do****@****rma.com
What is Daniel Ortiz's direct phone number?
Daniel Ortiz's direct phone number is .617.491*****
What schools did Daniel Ortiz attend?
Daniel Ortiz attended University Of Georgia Graduate School Of Arts And Sciences, University Of Costa Rica.
What skills is Daniel Ortiz known for?
Daniel Ortiz has skills like Molecular Biology, Biochemistry, Cell Biology, Lifesciences, Cell Culture, Biotechnology, Western Blotting, Genetics, Life Sciences, Protein Chemistry, Rt Pcr, Immunohistochemistry.
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