Darren Anthony Email & Phone Number

San Francisco, CA, US

South San Francisco, California, US

San Jose, California, US

• Helped oversee the fermentation group’s research while focusing on tracking progress on Smartsheet, implementing workflows, removing research barriers, and maintaining alignment across the group
• Managed the fermentation lab by sourcing materials/equipment and creating/maintaining vendor relationships
• Led cross-functional team meetings to foster communication, maintain structure, and optimize group efficiency
• Managed the creation of a searchable Smartsheet for indexing all past and current experiments for documentation and reporting purposes

• Researched scaling an MSC bioprocess from T-flasks to bioreactors while maximizing key process metrics
• Screened biomaterials to optimize cell-substrate attachment, proliferation, and harvest
• Documented experiments using Smartsheet to communicate progress to stakeholders
• Played a key role in generating and delivering material needed to support product prototyping and testing
• Served as the main analyst in maintaining and operating the Roche Cedex Bio HT Analyzer for metabolite analysis
• Spearheaded various improvements in organization such as naming systems and document/spreadsheet templates

Hayward, California, US

• Researched batch/fed-batch fermentation process development using 1L and 2L Sartorius bioreactor systems while meticulously analyzing mass and carbon balances from each experiment
• Presented weekly reports to scientists on fermentation runs, and providing initial QA on fermentation run data
• Supported a technology transfer to 25,000 L scale by executing control runs to mimic CMO protocol, validating seed vials, testing enzymes, and measuring C* and kLa for OUR scale-up, and providing on-site supervision to.
• Collaborated with the CMO facility on a Smartsheet dashboard to report process data back to HQ in real time
• Researched reaction kinetics — the effect of catalyst resin particle size on internal mass transfer limitations
• Designed and partially constructed a pilot-scale continuous distillation column for in-house product purification

Hayward, California, US

• Prepared various stock solutions to support fermentation research and operated bioreactors under scientist supervision
• Investigated OD to DCW correlation, characterizing noise and error and optimizing for precision and accuracy
• Created a spreadsheet-based inventory management system to enable COGS data analysis and streamline purchasing
• Documented contributions by submitting monthly progress reports to Asana to help enable progress tracking

South San Francisco, California, US

• Investigated the effect of depyrogenation on vial-to-vial interactions to increase efficiency of biological manufacturing
• Liaised with manufacturing personnel to develop a needed realistic downscale study to address large scale inefficiencies
• Developed a mathematical model that will concretely correlate manufacturing conditions to vial handling efficiency
• Worked in a group that coordinates technology transfers, and assisted in the process change to a controlled ice nucleation (CIN) lyophilization cycle
• Receiving training from my cross functional group in a matrixed work environment

San Diego, CA, US

• Developed methods for cleaning verification via HPLC to support manufacturing and analytical development
• Documented experiments in laboratory notebooks while complying with all SOPs and GLP/GMP practices

Boston, MA, US

• Investigated dissolution behavior of Orkambi (Lumacaftor/Ivacaftor), the only drug(s) that treat the underlying cause of Cystic Fibrosis.
• Prepared experimental formulations in order to gain a mechanistic understanding of the dissolution behavior of solid oral dosage forms on stability
• Utilized several analytical techniques to systematically analyze relevant parameters affecting in-vitro dissolution behavior, such as moisture content, hardness, crosslinking, viscosity, microstructure, and UV-Vis.
• Presented my project results to the Technical Operations Department and in a company-wide poster session

La Jolla, CA, US

• Investigated methods of algal cell lysis via shear force for purposes of extracting lipids for algal biofuel synthesis
• Practiced aseptic technique to prepare phytoplankton media, farm algal strains, and conduct experiments
• Used findings to design and 3-D print a prototype for mechanical algal cell lysis

New York, NY, US

• Presented to and energized our student body about the professional and social opportunities provided by AIChE.
• Increased membership from 168 to 202 (23% increase) during my term.

Redwood City, California, US

• Performed a rigorous and intensive characterization of IPG’s and analyzed subsequent data to set up Nevro HQ’s first gold-verified test stations for their product, a high-frequency lower back stimulant
• Developed test protocol for the company to present to their contracted manufacturers, increasing the quality of their manufactured devices
• Cooperated with a software vendor to increase the quality of Nevro's test software and increase the efficiency of their product testing

• Gained experienced in a fast paced and dynamic work environment where my responsibilities included picking golf balls, preparing members' golf bags, cleaning members' golf clubs, maintaining the driving range, and.
• Learned valuable skills such as a teamwork, adapting quickly, and multitasking.

• Met bi-weekly with a struggling high school chemistry student and raised her grade from a D+ to B by the end of the semester.

Bachelor Of Science (Bs), Chemical Engineering

Physics