Daryn Michael Email & Phone Number

Baglan Industrial Park, Port Talbot

Cultech Ltd is a South Wales based SME specialising in the research, development and analysis of innovative products for the nutraceutical industries in the UK, Europe and North America.

Port Talbot, S.Wales

Cultech Ltd is a South Wales based SME specialising in the research, development and analysis of innovative products for the nutraceutical industries in the UK, Europe and North America.

Port-Talbot Industrial Park

Cultech Ltd is a South Wales based SME specialising in the research, development and analysis of innovative products for the nutraceutical industries in the UK, Europe and North America.

School Of Biosciences, Cardiff University

Cardiovascular disease results in more deaths, globally, than any other ailment. A major contributing factor to its pathology is atherosclerosis; an inflammatory disorder characterised by the development of fibrotic plaques within arterial walls. Key to the progression of atherosclerosis is macrophages that contribute to plaque development by transforming into lipid-loaded foam cells upon internalization of modified lipoproteins. Accumulation of such foam cells in the arterial wall initiates… Show more Cardiovascular disease results in more deaths, globally, than any other ailment. A major contributing factor to its pathology is atherosclerosis; an inflammatory disorder characterised by the development of fibrotic plaques within arterial walls. Key to the progression of atherosclerosis is macrophages that contribute to plaque development by transforming into lipid-loaded foam cells upon internalization of modified lipoproteins. Accumulation of such foam cells in the arterial wall initiates the formation of fatty streaks that subsequently develop into advanced plaques that are prone to rupture. Clearly, macrophage lipid metabolism and foam cell biology represents a key avenue of research during the ongoing search for novel therapeutic targets that can be used in the clinical intervention of atherosclerosis-Differential regulation of macropinocytosis contributes to foam cell formation in THP-1 macrophages. -The role of Phosphoinositide 3-kinase during foam cell formation. Show less

Cardiff School Of Biosciences, Cardiff University

-TGF-β inhibits the uptake of modified low density lipoprotein by human macrophages through a Smad-dependent pathway.-Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages.

University Of Wales, College Of Medicine

-The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell.

Doctor Of Philosophy (Phd), Medical Biochemistry, Pass

Regulation of mucin 16 gene expression in the human peritoneal mesothelial cell.

Bachelor Of Science (Bsc), Biochemistry With Molecualr Biology, Second Class, First Division Hons