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Summary experience:Pioneering computational chemist who has repeatedly taken early stage ideas from germination to success ∎ The only person who can claim primary contributions to three of the biggest computational molecular modeling platforms (AMBER, Schrodinger, Discovery Studio) ∎ Vision to see both big picture and deal with details ∎ Exemplary communications skills including ability to present technical material to non-technical audiences ∎ Out-of-box thinker able to manage multiple clients in dotted line relationships Milestones include: First author of several versions of Amber (most used molecular modeling package in the world) String of early, seminal publications in field of Free Energy Perturbation (FEP) Nearly 70 publications, the majority as primary author, widely cited (ResearchGate score 35) Product Manager: Developed BioLuminate biologics structure design platform for Schrödinger, from ground up. Most successful product launch in their history. First biologics package to market. Product manager of the very first commercialized molecular modeling package, Discover; Helped launch Biosym Technologies (now Accelrys/Biovia); Product Manager & Director Customer Experience for Cyrus Biotechnology: Providing first commercialization of Rosetta Protein Design as Google-based SaaS First degree from UC Berkeley in modern computational chemistry Helped establish Vertex Phama's reputation in the area drug design through prolific publication. First person to provide formal avenue for music promotion on the Internet---Focus areas: Computational chemistry; molecular modeling; protein design; antibody design; software design; software program management; programming; structure-based drug design; molecular docking; methodology development for small molecule design, protein design, and molecular triage; new molecular scoring functions; free energy calculations; NMR refinement methods; molecular dynamics. Excellent writing and verbal skills.
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Vice President Of ProductQsimulate Jan 2020 - PresentBoston, Massachusetts, UsVP of Product QSimulate. We're a startup changing how quantum mechanics fits into the drug discovery and materials discovery ecosystems with the first QM platform that scales massively on a distributed memory platform. -
Product Manager And Director Of Customer ExpereienceCyrus Biotechnology Nov 2017 - Aug 2019Seattle, Washington, Us∎ Manage the company's SaaS product, and also serve as the director of customer experience, translating external customer experience to internal developer direction. ∎ As part of the executive team, help develop corporate strategy. ∎ Project manager for several milestone-based collaborative projects between the company and customers∎ Provide pre-sale and post-sale support and managed our customer-facing support team and strategy. Cyrus Biotechnology is the spin-out from Rosetta Commons focused on commercializing the renowned Rosetta suite of software, offering an easy-to-use GUI thin client SaaS modeling interface to a Google cloud implementation of Rosetta and its many options and dependencies. -
Director / Product Manager Biologics Software Platform And Senior ScientistSchrodinger Oct 2010 - Jun 2017New York, New York, UsDirector and Product Manager of the biologics software platform and Senior Scientist.Responsible for the biologics software platform marketed as BioLuminate, including market research, leading design and implementation, providing pre-sales support and presentations (both talks and workshops) and contributing some post-sales support. Internally, this required excellent skills at developing cross-team internal buy-in to gather resources and push implementation. Externally, this required frequently presenting at an appropriate level and with a focused story to open doors in a new market not well versed in the product. Brought on board to create the platform from ground zero. It became Schrodinger's most successful new software launch. In addition to managing the biologics platform, I participated in basic research in various areas related to protein design, antibody prediction, antibody liability assessment and free energy perturbation (FEP). -
CeoDapper Research Apr 2010 - Sep 2010Consulting services in computational chemistry and molecular modeling. -
Computational Chemist IiiThe Broad Institute At Mit Dec 2007 - Mar 2010Cambridge, Ma, UsLead computational chemist in the Stanley Center for psychiatric research, with research encompassing all aspects of theoretical chemistry, including hit identification, hit-to-lead optimization, protein modeling, etc. -
CeoDapper Research Jul 2004 - Nov 2007Development and characterization of high-throughput ligand scoring functions– FURMASA (simplified function based on an MD grid and a surface area term)– ZIPAP (molecular scoring function derived from experimental potential of mean force data)– MM-PBSA (combined molecular mechanics and Poisson-Boltzmann energies)
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Principal InvestigatorVertex Pharmaceuticals Apr 1991 - Jun 2004Boston, Ma, UsVery early employee of Vertex (employee number < 50). Focused on developing, implementing, testing and deploying new methodologies related to structure-based computational design. Also participated in core drug discovery efforts. Specific areas of application include: free energy calculations (FEP); de novo drug design; NMR refinement methods; improved screening energy functions.SImultaneously supported the AMBER modeling package as first author. AMBER is the most widely used molecular modeling package in the world. EXTENSIVE publication record. -
Product Manager, Discover ProgramBiosym Technologies (Now Accelrys / Biovia) May 1985 - Dec 1986Founding employee at this startup that later became Accelrys and is now Biovia. I was the Product Manager / Program Leader for the Discover platform, our primary product. In addition to leading the program development team, I was the primary customer-facing spokesperson and contact for Discover users (both commercial and academic) throughout the world.The commercialization of Discover represented the first commercialization of a structure-based drug design package.
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Manager, Record DepartmentStanford Bookstore Sep 1979 - Jun 1980Full responsibility for managing the large record department of the then-independent Stanford University Bookstore: Inventory/Ordering/Promotion/Organization.
David Pearlman Skills
David Pearlman Education Details
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Stanford UniversityChemistry -
University Of California, BerkeleyChemistry
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University Of California, San FranciscoComputational Chemistry
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El Camino Real High School
Frequently Asked Questions about David Pearlman
What company does David Pearlman work for?
David Pearlman works for Qsimulate
What is David Pearlman's role at the current company?
David Pearlman's current role is Vice President of Product at QSimulate.
What is David Pearlman's email address?
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What is David Pearlman's direct phone number?
David Pearlman's direct phone number is +161789*****
What schools did David Pearlman attend?
David Pearlman attended Stanford University, University Of California, Berkeley, University Of California, San Francisco, El Camino Real High School.
What skills is David Pearlman known for?
David Pearlman has skills like Computational Chemistry, Molecular Modeling, Drug Design, Docking, Start Ups, Physical Chemistry, Biotechnology, Protein Chemistry, Organic Chemistry, Drug Discovery, Lifesciences, Chemistry.
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