Senior Principal Scientist
Current
Apr 2022 - Present
AeroLeads people directory · profile
David Didio Email & Phone Number
Senior Principal Scientist with Experience in Protein and mRNA Purification Processes
at
Tessera Therapeutics
1 work email found
@celgene.com
LinkedIn matched
✓ Verified August 2026
4 data sources
Profile completeness 100%
Current company
Role
Senior Principal Scientist with Experience in Protein and mRNA Purification Processes
Location
Medford, Massachusetts, United States
Who is David Didio? Overview
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Quick answer
David Didio is listed as Senior Principal Scientist with Experience in Protein and mRNA Purification Processes at Tessera Therapeutics, based in Medford, Massachusetts, United States. AeroLeads shows a work email signal at celgene.com and a matched LinkedIn profile for David Didio.
David Didio previously worked as Senior Principal Scientist at Tessera Therapeutics and Senior Principal Scientist at Bristol Myers Squibb. David Didio holds Master'S, Pharmacology from Upstate Medical University.
Company email context
Email format at Tessera Therapeutics
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{first_initial}{last}@celgene.com
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Profile bio
About David Didio
Protein purification scientist with experience using current downstream and process analytical technologies in the development of purification processes for biological molecules expressed in mammalian and bacterial expression systems. In current role responsible for the process development for pre-clinical and clinical/FIH programs and process characterization for late-stage programs. Experience managing programs externally with CMOs and internal process development, technical transfer and process scale-up and modeling. Successfully completed multiple FIH programs. Knowledge and experience with process characterization and viral clearance studies. Responsible for authoring and review of sections for IND and BLA applications.High Throughput and Laboratory Automation: Responsible for the implementation of high throughput instrumentation and execution of downstream process development and process characterization studies. Experience with laboratory automation includes scripting and integration of analytical instrumentation for high throughput workflows. Additional experience with HPLC and other instrumentation to support high throughput workflows to streamline process development timelines.Evaluation of new technologies and platforms. Various positions on CMC teams and working in cross functional teams with analytical, upstream and drug product development to support program development activities and meet program timelines.
Listed skills include Technology Transfer, Purification, Biopharmaceuticals, High Throughput Screening, and 12 others.
Current workplace
David Didio's current company
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9 roles
David Didio work experience
A career timeline built from the work history available for this profile.
Senior Principal Scientist
Apr 2021 - Apr 2022
Principal Scientist
Oct 2019 - Mar 2021
Senior Scientist
Apr 2017 - Oct 2019
Senior Downstream Development Engineer
Shire
Dec 2015 - Mar 2017
Scientist, Process Development, Cmc
Sep 2013 - Aug 2015
Scientist
• Protein Purification Scientist in Biologics Process Science Group Working Independently and in Cross-Functional Teams to Develop Downstream Purification Processes for Early and Intermediate-Stage Biological Molecules Expressed In Bacterial Expression Systems• Downstream Project Lead for Scale-Up and Technical Transfer of Investigational Therapeutic for Phase I GMP Manufacture – Representation on CMC Team; Setting TPP(s), CQA(s), and CPP(s). Additional Responsibilities for Project Budget, Scheduling, and Coordinating across Functional Areas to Meet Project Timelines
Feb 2012 - Sep 2013
Sr. Professional
• Project Lead in the Development of Custom Affinity Ligand(s) for Candidate Therapeutic Molecules with Third-Party Vendor(s)• Design and Execution of Development and Process Characterization Studies for Regulatory Submissions• Expertise in Chromatographic Separations, Including: Hydrophobic Interaction, Ion-Exchange, Size-Exclusion, Reverse-Phase, Mixed-Mode and Affinity Chromatography• Expertise in High-Throughput Screening Techniques and Laboratory Automation – Using TECAN Freedom Evo 100 and 200 Systems and EvoWare Software• Expertise with Standard Preparative and Analytical Technologies: AKTA Explorer, Pilot, and AKTA Ready and Unicorn Software; HPLC with Agilent and Waters Platforms and Empower Software; Caliper LabChip and MF-UF Applications• Experience in Standard Molecular Biology Techniques, Including: DNA/RNA Preparation, IEF, SDS-PAGE, 2D-DIGE• Knowledge of FDA and ICH Guidelines and Implementation of Quality by Design Principles in the Development of Downstream Purification Processes and the Technical Transfer of Laboratory-Scale Purification Processes for Phase I and Phase II GMP Manufacture• Knowledge of Design of Experiments Principles for Process Development Methodologies and the use of JMP for Statistical Analyses of Process Development Results• Working in Multi-Disciplinary Groups to Coordinate Development Projects Within Assigned Timelines• Trained New Employees in Various Aspects of Downstream Purification including Good Laboratory Practices, Analytical Method Development, and Preparative Chromatography Theory and Techniques
Aug 2008 - Feb 2012
Associate Scientist
• Research Scientist in Bioprocessing and Protein Purification Development Group• Developed Novel On-Column Disaggregation Processing Step for the Recovery of Functional Monomeric Material from High Molecular Weight Species in Affinity Chromatography• Expertise in Protein Refolding and Early to Late-Stage Biological Purification Development of Recombinant Fc-Proteins and Monoclonal Antibodies.• Expertise in Technical Transfer of Laboratory-Scale Purification Processes to Pilot and Manufacturing-Scale and cGMP Regulations • Designed and Performed Development and Process Validation Studies for Regulatory Submissions• Composing Technical Documents for Biological Licensing Application • Working in Multi-Disciplinary Groups to Coordinate Development Projects Within Assigned Timelines• Experience in Project Management and Manager of People
Apr 2004 - May 2008
1 education record
David Didio education
-
Upstate Medical University
FAQ
Frequently asked questions about David Didio
Quick answers generated from the profile data available on this page.
What company does David Didio work for?
David Didio works for Tessera Therapeutics.
What is David Didio's role at Tessera Therapeutics?
David Didio is listed as Senior Principal Scientist with Experience in Protein and mRNA Purification Processes at Tessera Therapeutics.
What is David Didio's email address?
AeroLeads has found 1 work email signal at @celgene.com for David Didio at Tessera Therapeutics.
Where is David Didio based?
David Didio is based in Medford, Massachusetts, United States while working with Tessera Therapeutics.
What companies has David Didio worked for?
David Didio has worked for Tessera Therapeutics, Bristol Myers Squibb, Celgene, Shire, and Ambrx.
How can I contact David Didio?
You can use AeroLeads to view verified contact signals for David Didio at Tessera Therapeutics, including work email, phone, and LinkedIn data when available.
What schools did David Didio attend?
David Didio holds Master'S, Pharmacology from Upstate Medical University.
What skills is David Didio known for?
David Didio is listed with skills including Technology Transfer, Purification, Biopharmaceuticals, High Throughput Screening, Hplc, Design Of Experiments, Quality By Design, and Gmp.
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