Assay development for voltage-gated and ligand-gated ion channel drug targets using planar patch clamp systems (QPatch, Port-o-patch)

Participated in comprehensive Bioinformatics translational Drug Safety project: extraction of Blood Chemistry data, data cleaning and export (Spotfire) for database creation Acted as Study Director to coordinate the efforts of 5 functional groups, globally, to deliver pre-clinical Alzheimer's Disease biomarker validationWorked collaboratively and drove performance to deliver a first-of-its-kind study to link human clinical data in cognition with pre-clinical rodent dataStrategically planned 5 studies to maximize impact and value for clinical programs within the Psychiatry and Alzheimer's Disease biomarker portfoliosCollaborated with Biotech company in the development of new technology (OpusXpress®) and developed its use for preclinical screening, leading to the AstraZeneca Global Scientific and Technical Achievement and Gateway Awards Led project as Team Leader to leverage support from key stakeholders, at multiple levels of the company, in order to secure resources to drive project forward Worked cross-functionally with members of Discovery, Clinical Development and Legal to deliver to project objectivesEngaged customers in development of assays for clinical projects in order to support translational science plansManaged Neuroscience Department activities to drive and deliver data for Schizophrenia and Alzheimer's Disease projectsMentored and trained interns, colleagues and guest investigators in the use of OpusXpress® TEVC system and rodent surgeries

Evaluated GABAA receptor profile using TEVC in xenopus oocytes

2 sections laboratory, ~25 students each