David Howe Email and Phone Number
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David Howe personal email
Physician-Scientist with 20+ years of experience across all stages of drug development in large pharma and small biotech in multiple disease areas including respiratory, inflammation and autoimmunity, immuno-oncology, headache, neurodegeneration, chronic pain, women's health and obstetrics.Expertise in translational and experimental medicine leading initiatives to identify new targets, develop pharmacodynamic biomarkers and patient stratification biomarkers, and design of human pharmacology and exploratory clinical efficacy studies.Experience with conduct of pivotal (confirmatory efficacy) studies supporting registration and regulatory interactions (scientific advice, end of phase 2, NDA (US) & mutual recognition procedure Europe))Extensive experience supporting business development (venture capital, in-licencing, partnering and out-licencing activities)Significant experience in senior management roles at Soseiheptares, Medimmune and TopivertClinical and research background (14 years) in Obstetrics & Gynaecology/Fetal-Maternal Medicine before joining the pharmaceutical industry.
Muna Therapeutics
View- Website:
- munatherapeutics.com
- Employees:
- 56
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Vice-President And Head, Early Clinical DevelopmentMuna TherapeuticsTonbridge, Gb
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Head Of Clinical Development, NeuroscienceAstrazeneca Mar 2023 - PresentCambridge, Cambridgeshire, Gb -
Vice President, Head Of Experimental MedicineSosei Heptares Aug 2018 - Mar 2023Tokyo, Tokyo, JpMember of the leadership team and Head of Experimental Medicine.Heptares is focused on discovery and development of drugs targeting G Protein Coupled Receptors. The company currently concentrates on three therapeutic areas (CNS disorders, Immunology and Oncology) -
Senior DirectorMedimmune Oct 2014 - Aug 2018Senior Director and group lead in Respiratory, Inflammation and Autoimmunity therapeutic area.Responsible for early development through to phase 3 investment decision for novel Biologics for respiratory, inflammation and autoimmune diseases (COPD, asthma, rheumatoid arthritis, Sjögren's syndrome, ANCA vasculitis, ITP) including submission of CTA/IND and preparation for and participation in End of Phase 2 discussions with FDA and EMA.
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Head Of Translational MedicineTopivert Pharma Limited Oct 2012 - Sep 2014London, GbTopivert is a VC funded start-up.Member of the leadership team.Responsible for translational and early clinical development planning for novel small molecule tyrosine kinase inhibitors for gastrointestinal and ophthalmic indications -
Medical DirectorGsk Jul 2009 - Sep 2012Brentford, Middlesex, GbMember of the leadership team of the Experimental Medicine Discovery Performance Unit within the Immuno-Inflammation Centre for Excellence in Drug Discovery.Responsible for early clinical development (through to PoC) of novel immunomodulatory small molecules and Biologics for rheumatoid arthritis, inflammatory bowel disease, type 1 diabetes, graves eye disease, myasthenia gravis. Member of late stage (full development) teams responsible for translational medicine contributions to projects for inflammatory bowel disease and type 1 diabetes including preparation for and participation in End of Phase 2 discussions with FDA and EMA. -
Medical DirectorPfizer Sep 2004 - Jun 2009New York, New York, UsGlobal Clinical Lead for depo-provera including medical lead for regulatory submission of depo-provera SC for treatment of endometriosis in US and EMA and design and conduct of post-approval commitments to assess potential for adverse effects on bone metabolism.Medical Director/Translational Medicine lead Gastrointestinal & Genitourinary Therapeutic area responsible for early clinical development (through to PoC) of novel small molecules and Biologics for pre-eclampsia, endometriosis, contraception, female sexual dysfunction, Member of the Disease Area Working Group responsible for evolution of therapeutic area strategy to focus on fibrotic conditions (endometriosis, kidney disease, liver disease) and chronic pelvic pain (endometriosis, interstitial cystitis, chronic prostatitis). -
Clinical LecturerUniversity Of Glasgow Sep 2001 - May 2004Glasgow, Glasgow, GbObstetrics & Gynaecology -
Research FellowCornell University Oct 2000 - Sep 2001Ithaca, Ny, UsVisiting research fellow laboratory for newborn and pregnancy research -
Research FellowUniversity Of Toronto Nov 1999 - Sep 2000Toronto, Ontario, CaVisiting research fellow department of physiology -
Clinical LecturerThe University Of Edinburgh May 1998 - Nov 1999Edinburgh, GbObstetrics & Gynaecology
David Howe Skills
David Howe Education Details
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The University Of EdinburghMedicine -
The University Of EdinburghMedicine
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The University Of EdinburghPhysiology
Frequently Asked Questions about David Howe
What company does David Howe work for?
David Howe works for Muna Therapeutics
What is David Howe's role at the current company?
David Howe's current role is Vice-President and Head, Early Clinical Development.
What is David Howe's email address?
David Howe's email address is d.****@****net.com
What schools did David Howe attend?
David Howe attended The University Of Edinburgh, The University Of Edinburgh, The University Of Edinburgh.
What skills is David Howe known for?
David Howe has skills like Clinical Development, Translational Medicine, Drug Development, Clinical Trials, Clinical Research, Medicine, Drug Discovery, Biomarkers, Immunology, Physiology, Reproductive Endocrinology.
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