David Jacoby Email and Phone Number
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https://www.biomarin.com/our-science/our-scientists/david-jacoby-md-phd. Experienced development physician-scientist leading pipeline/portfolio advancement and early clinical development. Responsible for clinical strategy of pipeline, development thesis of programs, stage advancement decision-making, clinical development to proof of concept across several genetic indications, including neurodevelopmental disorders, cardiomyopathies and metabolic diseases. Successful record of development with registration of Brineura for Battens disease and Palynziq for PKU. Led translation of AAV gene therapy for hemophilia A and biologicals for MPS 3B into the clinic. Experience developing biologics, gene therapy, antisense oligonucleotides, and small molecules for single gene disorders of high unmet need in neurology, hematology, metabolic and pediatric disorders. Introduced several compounds across technical platforms into the IND/CTA stages and managed programs through proof of concept, pivotal studies and submission/approval.Specialties: NeurologyRare/orphan diseasesMolecular and clinical geneticsMovement disordersDystoniaBipolar depressionAbdominal imagingRegulatory submissionsClinical development plansPublicationsIND-NDAPresentations
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Senior Vice President Head Of Clinical DevelopmentUltragenyxSan Rafael, Ca, Us
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Svp Head Of Clinical DevelopmentUltragenyx Aug 2024 - PresentNovato, California, UsStarting new position as head of clinical at Ultragenyx -
Group Vice President, Biomarin FellowBiomarin Pharmaceutical Inc. Mar 2023 - Aug 2024San Rafael, Ca, Us -
Fellow; Vice President Discovery MedicineBiomarin Pharmaceutical Inc. Jan 2020 - Aug 2024San Rafael, Ca, UsLeadership of Discovery Medicine, the early stage clinical development function at BioMarin. Coordinate portfolio assessments, lead cross-functional discovery, diligence and business development activities aimed at increasing pipeline and research programs. Leadership of research and early development teams. Work with CSO, CEO, President R&D to development research portfolio strategy.
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Vp, Clinical Sciences Fellow, Head Of Clinical SciencesBiomarin Pharmaceutical Inc. Feb 2018 - Jan 2020San Rafael, Ca, UsLeadership of the clinical development group at BioMarin, overseeing development stage pipeline projects.
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Executive Group Director, Clinical SciencesBiomarin Pharmaceutical Inc. Jun 2016 - Feb 2018San Rafael, Ca, UsLed the team supporting the successful registration of Brineura for the CLN2 form of Batten's disease, a rare pediatric neurodegenerative disorder. Multiple programs managed including PKU, MPS III, hemophilia A. IND initiation of AAV gene therapy for fVIII hemophilia. Leading HDAC platform for Friedreich's ataxia. Broad development and regulatory support for multiple INDs through to successful registration.
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Senior Medical Group Leader NeuroscienceBiomarin Pharmaceutical Inc. Dec 2012 - Jun 2016San Rafael, Ca, UsClinical development for rare and neurogenetic diseases. Translational research experimental neurobiology.
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Head Of Clincal DevelopmentRepligen Corporation Jun 2009 - Dec 2012Waltham, Ma, UsMedical monitorProtocol development, statistical analysis and objective setting for Phase I-III clinical studiesClinical development for programs in pancreatic imaging, bipolar depression, Friedreich's ataxia, Spinal Muscular atrophy, Huntington's disease and memory disordersTranslational research neuroscienceTranslational research rare disordersRegulatory submissions including NDA, MAARegulatory presentationsAcademic presentationsBusiness development (in- and out-licensing) -
Medical DirectorRepligen Corporation May 2006 - Jun 2009Waltham, Ma, UsHead of Clinical Development and Regulatory Affairs. Clinical programs in pancreatic imaging, bipolar depression, spinal muscular atrophy and Friedreich's ataxia.
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Independent ConsultantIndependent Jun 2001 - May 2006
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Medical DirectorSerono, Inc. 2000 - 2001Medical monitor phase I-III clinical trialsRegulatory submissions and presentationsProtocol designBusiness development (in-licensing)
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Associate NeurologistMassachusetts General Hospital Jun 1998 - Sep 2000Boston, Ma, UsMovement disorder clinicDirector, dystonia clinicFellow, neurogenetics unit -
Research Fellow, Molecular NeurogeneticsMassachusetts General Hospital Jun 1996 - Jun 1998Boston, Ma, Us
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Clinical Fellow, Movement Disorders UnitMassachusetts General Hospital Jun 1996 - Jun 1998Boston, Ma, Us
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Resident, Adult NeurologyMassachusetts General Hospital Jul 1992 - Jun 1996Boston, Ma, Us
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Fellow, Viral ImmunopathologyThe Scripps Research Institute Jun 1981 - Jun 1984La Jolla, California, Us
David Jacoby Skills
David Jacoby Education Details
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University Of Pennsylvania School Of MedicineMolecular Biology -
Swarthmore CollegeBiology
Frequently Asked Questions about David Jacoby
What company does David Jacoby work for?
David Jacoby works for Ultragenyx
What is David Jacoby's role at the current company?
David Jacoby's current role is Senior Vice President Head of Clinical Development.
What is David Jacoby's email address?
David Jacoby's email address is dj****@****hoo.com
What is David Jacoby's direct phone number?
David Jacoby's direct phone number is +141549*****
What schools did David Jacoby attend?
David Jacoby attended University Of Pennsylvania School Of Medicine, Swarthmore College.
What are some of David Jacoby's interests?
David Jacoby has interest in Boating, Kids, Gardening, Outdoors, Investing, Electronics, Home Improvement, Shooting, Sports, Home Decoration.
What skills is David Jacoby known for?
David Jacoby has skills like Clinical Trials, Clinical Development, Neuroscience, Neurology, Biotechnology, Clinical Research, Regulatory Affairs, Medicine, Rare Diseases, Genetics, Product Development, Translational Research.
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