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Experienced medicinal chemist now working with Pharmaron (www.pharmaron.com) to support our clients on the East Coast.Business Development Executive in the discovery, preclinical and CMC spaces at Pharmaron. Extensive, diverse experience in the design and laboratory synthesis of drug-like molecules. Collaborated with multiple CROs/CMOs in Asia and Europe to rapidly achieve desired project goals. Demonstrated record of success in target identification/validation, lead identification, and lead optimization to preclinical candidate selection. Experienced in intellectual property protection and issues related to freedom-to-operate in a pharmaceutical setting, improvement of drug metabolism/pharmacokinetics (DMPK), structural biology and computational chemistry, prodrugs, transition metal catalysis, proprietary synthetic reagent collection design and oversight, small molecule library design and synthesis, and peptide chemistry. Successfully prosecuted targets, including enzyme inhibitors, G-protein coupled receptors, and protein-protein interactions. Additional experience and expertise in immuno-oncology, Gram-positive and Gram-negative bacterial infections, diabetes, obesity, atherosclerosis, hypertension, and neurological disorders.
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Senior Director Business DevelopmentPharmaron Oct 2021 - PresentBeijing, Cn -
Director Of Business DevelopmentPharmaron Oct 2019 - Oct 2021Beijing, Cn -
Team LeadVenenum Biodesign, Llc May 2016 - Sep 2019Hamilton, Nj, UsDiscovery and development of novel immuno-oncology agents -
Director Research And DevelopmentAcceledev Chemical Llc Mar 2015 - Jul 2015Cranbury, Nj, UsDesigned, developed, and implemented synthetic organic chemistry routes to various APIs, intermediates, and fine chemicals. Generally worked on preparative lab scale (hundreds of grams to kilograms/up to 30 L vessels). Supervised all aspects of daily laboratory operations, reaction planning, maintenance, and ordering. -
Technical Sales ExecutiveWuxi Apptec Nov 2014 - Feb 2015Shanghai, Shanghai, Cn -
Senior Account ExecutiveWuxi Apptec Jun 2014 - Nov 2014Shanghai, Shanghai, Cn -
Principal Scientist-Medicinal ChemistryMerck 2011 - 2013Rahway, New Jersey, UsWorked on small molecule synthesis, scale-up, and purification while actively following SAR from multiple lead classes in order to make informed decisions on future synthetic efforts. Collaborated with internal and external chemists in the discovery and optimization of novel classes of compounds for treatment of atherosclerosis and Alzheimer’s disease. Traveled regularly to partner sites in Shanghai and Rome to set up collaborations, review program status, provide updates and reaffirm goals. -
Research Fellow-Medicinal ChemistryMerck 2009 - 2011Rahway, New Jersey, UsResearch Fellow, Lead Optimization, External Discovery & Preclinical SciencesDirected medicinal chemistry programs that were run exclusively at external partner sites. Operated as an integral member of numerous cross-functional teams. Collaborated with the Rapid Analog Synthesis group at WuXi Apptec for design and synthesis of targeted libraries in support of SAR development. Presented frequent program updates to senior-level management. Traveled regularly to Shanghai to meet with WuXi team and address chemistry issues, productivity, notebook compliance, and progress toward program goals. -
Senior Research Chemist-Medicinal ChemistryMerck 2008 - 2009Rahway, New Jersey, UsSenior Research Chemist, Target Validation & Lead Identification, Worked in a laboratory setting, performing synthetic organic chemistry transformations to rapidly identify novel targets for treatment of metabolic disorders and cardiovascular disease. Utilized both external chemistry support from WuXi Apptec as well as internal support from multiple associate chemists. -
Senior Research Chemist-Medicinal ChemistryMerck 2002 - 2008Rahway, New Jersey, UsSenior Research Chemist, Lead Optimization, Medicinal ChemistryProvided leadership to two recently graduated associate level chemists in the prosecution of medicinal chemistry lead optimization programs. Utilized techniques in synthetic organic chemistry and medicinal chemistry to progress two lead optimization programs. -
Graduate StudentUniversity Of Texas At Austin 1997 - 2002Graduate researcher in a synthetic organic chemistry laboratory under the tutelage of Professor Stephen F. Martin. Ph.D. Thesis: Novel Methodologies for the Synthesis of C-Aryl Glycosides and Progress toward the Synthesis of the C-Aryl Glycoside Natural Products Galtamycinone and Kidamycin
David Kaelin Skills
David Kaelin Education Details
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University Of Texas At AustinOrganic Chemistry -
Penn State UniversityOrganic Chemistry
Frequently Asked Questions about David Kaelin
What company does David Kaelin work for?
David Kaelin works for Pharmaron
What is David Kaelin's role at the current company?
David Kaelin's current role is Sr. Director, Business Development at Pharmaron.
What is David Kaelin's email address?
David Kaelin's email address is da****@****rck.com
What schools did David Kaelin attend?
David Kaelin attended University Of Texas At Austin, Penn State University.
What are some of David Kaelin's interests?
David Kaelin has interest in Children, Education, Poverty Alleviation, Science And Technology, Disaster And Humanitarian Relief, Animal Welfare, Health.
What skills is David Kaelin known for?
David Kaelin has skills like Organic Synthesis, Chemistry, Infectious Diseases, Drug Discovery, Medicinal Chemistry, Catalysis, Animal Models, Neuroscience, Alzheimer's Disease, Type 2 Diabetes, Obesity, Cardiovascular Disease.
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