Protein Engineering Leadership• Leader of a multidisciplinary teamresponsible for the isolation and optimization of antibodies / other proteins and peptides for therapeutic development. o Scientific leader with 18 years’ experience in biologics discovery and early development o Accountable for isolation and engineering of lead molecules for Respiratory, Inflammatory and Autoimmunity antibody projects: > 30 pre-clinical products deliveredo Manage Peptide Chemistry facility for MedImmune, supporting all cardiovascular and metabolic disease area projectso Manage new technology teamo Project Leadership: Project Leader for multiple pre-clinical projectsTechnology Management and Development• Accountable for development and maintenance of MedImmune’s core phage and ribosome display-based antibody platforms as well as peptide platforms• Early Developability Assessmento Led cross-R and D initiative to assess early developability of all antibody leads in LI/LO across MedImmune Led the development and implementation of novel high-throughput assays within ADPE for early assessment of developability (thermal stability, colloidal stability, accelerated stability assays) Chair Developability Team for early assessment of antibody stability – multifunctional cross-site Research and Development teamStrategic Management Responsibilities • Chair Technology Research Review Committeeo Responsible for oversight of all new in-house protein and peptide engineering technologieso Assessment and due diligence of external technology collaboration/in-licensing opportunities

Antibody Discovery and Protein Engineering