Manage a small group of scientists in a GLP bioanalytical environment. Oversee conduct of the bioanalytical portion of non-clinical and clinical studies. Organize and manage outsourcing activities to support clinical and non-clinical studies through immunocapture-LC/MS assays. Organize the purchase, installation and programming of Hamilton liquid handling automation systems. Develop rugged and sensitive LC/MS/MS bioanalytical assays for Oligonucleotide and NBE quantitation. Assist in special projects when LC/MS is needed for NBE analysis. Perform bioanalytical sample analysis under GLP conditions. Use, maintain, and calibrate Sciex and Micromass mass spectrometers. Use and maintain Waters Acquity UPLC systems, Eksigent MicroLC systems, Kingfisher bead handling systems and Tomtec Quadra3 liquid handling systems. Write study and validation reports in collaboration with other staff. Evaluate new technology for possible future use. Write, review and edit SOPs for a GLP environment.

Developed bioanalytical LC/MS/MS methods for use during pre-clinical and clinical study sample analysis. Troubleshot LC/MS/MS issues such as carry-over and sensitivity. Communicated with other groups and departments in an effort to minimize repeated work on specific studies. Maintained and calibrated Sciex and Micromass mass spectrometers. Assisted with GLP and non-GLP sample analysis. Wrote Study Reports summarizing study data, method performance and PK results. Contributed to training of less experienced staff.

Assisted in the growth and development of a small, start-up bioanalytical CRO. Participated in the set-up and organization of a new lab space. Responsible for planning of all laboratory tasks and metrology. Calibrated and maintained most laboratory equipment, including Sciex Mass Spectrometers and various types of pipettes. Conducted all sample analysis and GLP bioanalytical method validation. Contributed to various aspects of method development with increasing amounts of independence. Reviewed all SOPs and equipment maintenance procedures pertaining to the operation of a GLP laboratory. Wrote study, validation, and method reports to meet the needs of different clients.

Performed multiple LC/MS/MS assays in a high throughput bioanalytical laboratory under GLP conditions. Worked with multiple liquid handling systems used for Bioanalytical sample extraction (Tomtec, Packard) and various types of extraction (SPE, PPT, Liq-Liq). Assisted in bioanalytical method development. Validated various bioanalytical methods for multiple types of analytes, species and matrices. Trained in safe handling procedures of both controlled substances and biohazardous materials. Tuned LC/MS/MS systems and performed daily maintenance. Maintained centrifuges in a GLP laboratory.