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David S. is listed as Senior Scientist in Phage Display Antibody Discovery and Engineering Leads Breakthrough Cancer Immunotherapy at Sorrento Therapeutics, Inc., a company with 220 employees, based in San Diego, California, United States. AeroLeads shows a matched LinkedIn profile for David S..
David S. previously worked as Senior Scientist at Sorrento Therapeutics, Inc. and Senior Scientist at Schafer Foundation For Centriolar Research. David S. holds Post Doctoral Training from University Of California, San Diego - School Of Medicine.
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I am a Senior Scientist with specialized expertise in phage display antibody discovery and engineering. At Sorrento Therapeutics, I developed a VHH library from Camelid PBMCs and created various Humanized affinity maturation libraries. I have successfully delivered multiple antibodies for therapeutic development including CAR-T, CAR-NK,ADC, and BiTe, through high throughput screening and antibody engineering, many of which are in the process of patent application. Furthermore, I possess the proficiency to perform single B cell antibody screening from PBMCs. My knowledge base encompasses protein structure, mutation, and purification, as demonstrated through my Ph.D. research on the structure and function of proteins essential to human diseases. During this time, I deposited 6 protein structures to the PDB database, and my Ph.D. thesis was published in a highly esteemed journal with hundreds of citations from fellow researchers.I am also well-versed in yeast cell biology and molecular biology, having spent nine years at UCSD studying signal transduction of the secretory pathway using yeast genetics manipulation and phenotypic analysis. My work has resulted in several publications in renowned journals.My key skills include phage display, antibody library construction and engineering, epitope binning, SPR kinetics, protein structure analysis, Yeast genetics, Yeast-2-hybrid, cell-based assay, and DNA and RNA molecular cloning.
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San Diego, CA USA
Senior Scientist at Sorrento Therapeutics, Inc. since July 2018, specializing in antibody discovery and engineering using high-throughput phage discovery, antibody humanization and affinity maturation library construction and screening, antibody expression, purification and characterization by Octet and Biacore, structure-based antibody engineering, and.
Cincinnati, Ohio, United States
Senior Scientist at the Schafer Foundation for Centriolar Research from May 2017 to July 2018, working on centriolar research, including the correlation between multiple centrioles and cancer and the electromagnetic property of centrioles, and generating stable cell lines of multiple centrioles by lentiviral transduction of 293FT, U2OS, and HTB126.
La Jolla, California, United States
As an assistant project scientist, I focused on regulation of the exocyst assembly and disassembly, and the secretary pathway using protein-protein interaction analysis and yeast genetic manipulation. Specifically, I employed domain swapping techniques to rewire the Rab regulatory network and conducted functional analysis and confocal microscopy studies.
La Jolla, California, United States
My research was centered on the control of membrane trafficking and the recruitment of exocyst through Rab GTPases. I employed a range of methods such as yeast deletion library screening, yeast-2-hybrid screening, confocal fluorescence microscopy, and overexpression of proteins in mammalian cells to explore these mechanisms.
Hefei, China
My doctoral research centers on the structural biology domain, with a specific focus on investigating the solution structure of protein domains that play a critical role in human diseases. This research involves a variety of techniques, including cloning, expressing, purifying, and determining the structure of proteins. In addition, I conducted functional.
Other employees you can reach at sorrentotherapeutics.com. View company contacts for 220 employees →
Jon J. Allen
Colleague at Sorrento Therapeutics, Inc.
Chula Vista, California, United States, United States
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Avery Coyle
Colleague at Sorrento Therapeutics, Inc.
San Diego, California, United States, United States
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Tracy S.
Colleague at Sorrento Therapeutics, Inc.
United States, United States
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Moli L.
Colleague at Sorrento Therapeutics, Inc.
San Diego, California, United States, United States
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LX
Lu Xia
Colleague at Sorrento Therapeutics, Inc.
United States, United States
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Lin Lin
Colleague at Sorrento Therapeutics, Inc.
Raleigh-Durham-Chapel Hill Area, United States
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John Waldheim
Colleague at Sorrento Therapeutics, Inc.
San Diego, California, United States, United States
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Héctor Sulaimán
Colleague at Sorrento Therapeutics, Inc.
Mexico City Metropolitan Area, Mexico
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BR
Bill Raab
Colleague at Sorrento Therapeutics, Inc.
San Diego, California, United States, United States
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JZ
Jerry Zeldis
Colleague at Sorrento Therapeutics, Inc.
Minneapolis, Minnesota, United States, United States
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Quick answers generated from the profile data available on this page.
David S. works for Sorrento Therapeutics, Inc..
David S. is listed as Senior Scientist in Phage Display Antibody Discovery and Engineering Leads Breakthrough Cancer Immunotherapy at Sorrento Therapeutics, Inc..
David S. is based in San Diego, California, United States while working with Sorrento Therapeutics, Inc..
David S. has worked for Sorrento Therapeutics, Inc., Schafer Foundation For Centriolar Research, University Of California, San Diego - School Of Medicine, and University Of Science And Technology Of China.
David S.'s colleagues at Sorrento Therapeutics, Inc. include Jon J. Allen, Avery Coyle, Tracy S., Moli L., and Lu Xia.
You can use AeroLeads to view verified contact signals for David S. at Sorrento Therapeutics, Inc., including work email, phone, and LinkedIn data when available.
David S. holds Post Doctoral Training from University Of California, San Diego - School Of Medicine.
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