David Hans Email & Phone Number

Houston, Texas, United States

San Francisco Bay Area

• Developed statistical models, applied machine learning algorithms for analysis of clinical cancer genomic sequencing, gene expression data and diagnostic products using R, Python, and Unix Shell Scripting.
• Built bioinformatics pipelines to support ongoing biomarker discovery studies for advancing cancer drugs in clinic
• Vendor assessment and performance evaluation from tumor profiling doing mutation and copy number variation analysis. Performed differential gene expression analysis for biomarker discovery.

Columbus, Ohio Area

• Designed, implemented, analyzed, and validated bioinformatics pipelines to assist Principal Investigators in support of project objectives to solve problems in cancer genomics.
• Ran analysis programs in parallel on large computer clusters to integrate, organize and analyze program output for alignment, variant calling, differential gene expression and statistical analysis.
• Developed scripts using Bash, R, Python to parse, process, and analyze genome-wide data sets, focusing on NGS data such as RNA-seq, Exom-seq, ChIP-seq, Methyl-seq, and Proteomics

Houston, Texas Area

• Taught university level courses, supervised groups, and tutored individuals.
• Prepared lectures, assignments, and examinations for 50 students. Received high performance ratings from students.

Houston, Texas

• Built computational models in collaboration with clinicians and researchers from several hospitals and universities for host Tuberculosis bacteria interactions and gene-regulatory networks.
• Implemented optimization algorithms to estimate parameters from experimental data, did statistical and bioinformatics analysis to validate computational models.
• Mentored & trained new team members. Supervised and managed undergraduate research projects. Experienced in motivating, making decisions, delegating and tracking progress.

Blacksburg, VA

• Developed mathematical models of mitotic exit in yeast cell cycle.
• Proposed mathematical and biological basis for system-level decisions.

Greater Pittsburgh Area

Developed a computational model of influenza infection, simulated drug effectiveness, and characterized probabilistic outcomes of possible treatment scenarios.

Rahway, NJ

Analyzed optimal production parameters in vaccine development to maximize virus yield.

Doctor Of Philosophy (Ph.D.), Computational And Applied Mathematics, 3.87

Activities and Societies: SIAMDissertation: Mathematical Modeling of Virus Dynamics in Immunology

Master'S Degree, Mathematics

Tesi di Laurea: Variance Reduction Techniques in Monte Carlo Simulation

B.S., Mathematics

Activities and Societies: Chess ClubMerit based scholarship, and fellowship for outstanding degree in the university admission exam.