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David creates new business models and systems that progress fundamental technology and scientific research outcomes into patient impact through forming powerful cross-sector collaborations between industry, academia and medical research charities. His experience as VP Scientific Strategy in Vancouver provided valuable insight in to the Canadian life science environment and alternative models for translation of fundamental research.David’s career has focused on the application of early-stage technologies to address real-world problems; this is exemplified through his work across multiple clients and sectors at LifeArc, PA Consulting Group and his management roles at GSK.Prior to this, David was a medicinal chemist leading research in to new therapies across multiple therapeutic areas, including neuroscience, cardiology, pain and immune disease. His extensive knowledge of pharmaceutical sciences crosses drug discovery, preclinical development and technology development as well as scientific management and leadership.
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Svp Head Of Global Molecular ArchitectsEvotec Oct 2022 - PresentHamburg, DeMember of Global Drug Discovery Leadership and Core Site Leadership teams embedding strategy and operational delivery of 'Molecular Architects': a unique opportunity to fuse medicinal chemistry expertise with computational technologies and data science to deliver compressed time to preclinical development candidates. -
Svp Head Of In Silico R&DEvotec Apr 2022 - Oct 2022Hamburg, DeGenerating new in silico tools and technologies that integrate rapidly growing data sources with emerging AIML tools to advance drug discovery capability and probability of clinical success. -
Head Of Technology DevelopmentLifearc Jun 2018 - Mar 2022London, GbWithin the Centre for Therapeutic Discovery: Responsible for the identification, acquisition, development and implementation of novel or emerging technologies with the potential to accelerate and improve accuracy of drug discovery with a focus on relevance to human disease pathology: make it about the patient, make it faster and make it right.Examples include research and implementation of:• Virtual Reality for medicines design, huge and complex data analytics and 3-D image reconstruction• Antibody-drug conjugates to extend pharmacological windows and reduce ASEs• Antibody-Assisted Drug Discovery to drug difficult-to-access therapeutic targets• Extracellular vesicles for the robust and controllable penetration of the Blood-Brain Barrier• Bioinformatics, data science, AI and ML technologies for drug discovery.At a corporate level: Member of the Senior Leadership Team with responsibilities for strategy development and implementation. -
Chair, Neuroscience Therapeutic Area Leadership TeamLifearc Aug 2018 - Oct 2019London, Gb -
Head Of Innovation And InitiativesLifearc Apr 2013 - Jun 2018London, GbMember of the Senior Leadership Team, created new business models that advance and accelerate the delivery of patient impact by bringing together groups of researchers, companies and patient advocates that share a common goal, such as:• Dementia Consortium: A collaboration including ARUK and 5 pharmaceutical companies which collectively invested £4.5m over 4 years to translate 8 research projects to be ready for commercial development. With the principle of sharing the investment risk of early-stage neuroscience projects now being fully established, a second, larger Dementia Consortium is being considered• KidsCancer ACTNOW: A network of over 10 EU paediatric cancer charities and US foundation CureSearch for Children’s Cancer is building a US$100m Catapult fund to develop (or repurpose) oncology therapeutics for children with the support (knowledge and clinical insight) from several multinational pharmaceutical companies• Neuro-MAP: brings together 8 charities from the UK and US to co-fund the commercial development of clinical-stage therapeutic assets that have been de-prioritised by industry. The initiative has successfully advanced 4 new therapeutics over 3 years without needing to draw on the resources of the charity partners (Progressive MS, Parkinson’s and Alzheimer’s disease) -
Vice President Strategy And Analytics & Fellow In Translational ResearchAdmare Bioinnovations Jun 2017 - Dec 2017Canada, Ca[Formerly the Center for Drug Research and Development (CDRD)]Member of the Executive Team reporting to the CEO & President, led the development of a new scientific strategy to position CDRD as Canada’s national drug development catalyst through the translation and commercialisation of Canadian Life Science research output:• Responsible for the management and development of scientific strategy to increase the number, likelihood and speed of therapeutic targets transitioning from researcher to commercial partner• Responsible for ensuring the research portfolio reflected CDRD’s strategy and appetite for risk through managing a team of ‘Searchers’ seeking novel therapeutic approaches that address unmet need -
Principal Consultant In Pharmaceutical And Medicines Discovery Strategy And InnovationPa Consulting Group Jan 2007 - Apr 2013London, London, GbLeadership of multiple interdisciplinary teams of scientists, engineers and managing consultants to deliver innovation, technology and business transformation for blue chip clientsConsultant to the Pharmaceutical Industry leading multiple interdisciplinary teams of scientists, engineers and managing consultants to deliver innovation, technology and business transformation in life sciences and pharma.Specialised in innovation, technology scouting, externalisation and partnering strategy, alliance and partnership management, medicines discovery technologies, automated medicines design tools, technology assessment and transfer, business and strategy planning and technical due diligence. -
Technology Development ManagerGsk Jan 2001 - Jan 2007Brentford, Middlesex, GbResponsible for a suite of complex projects, comprising internal and external multidisciplinary teams, that developed new tools and technologies directed at accelerating drug discovery and medicines optimisation -
Principal InvestigatorGsk 1997 - 2001Brentford, Middlesex, GbResponsible for the introduction and adoption of medicinal chemistry principles into high-throughput chemistry library design resulting in smaller more effective libraries that explored drug-protein interactions and structure-activity relationships in novel therapeutic targetsMedicinal & synthetic chemistry, computational chemistry and cheminformatics -
Medicinal ChemistGsk 1989 - 1997Brentford, Middlesex, GbLeadership and prosecution of programmes of research delivering molecular tools and potential drug candidates, four of which entered clinical development leading to two successful new drugs launchedDesign of novel synthetic routes to new molecules that aid in the understanding of structure-activity relationships and contribute towards knowledge of the molecular interactions and physicochemical properties required for new therapeutic candidates. For example: neurological targets for pain and cognition, protein kinase targets for cardiac arrhythmia and autoimmune disorders, and G-protein coupled receptors for migraine
David Pardoe Skills
David Pardoe Education Details
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University Of BristolMedicinal Chemistry -
Nottingham Trent UniversityApplied Chemistry
Frequently Asked Questions about David Pardoe
What company does David Pardoe work for?
David Pardoe works for Evotec
What is David Pardoe's role at the current company?
David Pardoe's current role is SVP Head of Global Molecular Architects at Evotec.
What is David Pardoe's email address?
David Pardoe's email address is da****@****l.co.uk
What is David Pardoe's direct phone number?
David Pardoe's direct phone number is +120739*****
What schools did David Pardoe attend?
David Pardoe attended University Of Bristol, Nottingham Trent University.
What skills is David Pardoe known for?
David Pardoe has skills like Drug Discovery, Pharmaceutical Industry, R&d, Technology Transfer, Life Sciences, Medicinal Chemistry, Strategy, Technology Evaluation, Biotechnology, Open Innovation, Due Diligence, Drug Development.
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