Founder And Cso
CurrentLupagen is enabling bedside cell therapy by creating a closed loop autologous cell modification system lowering costs and increasing patient safety and convenience.
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@pfizer.com
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David Peritt is listed as Enabling In-Situ Generation of Therapeutic Cells at Lupagen, based in Greater Chicago Area, United States. AeroLeads shows a work email signal at pfizer.com, phone signal with area code 224, and a matched LinkedIn profile for David Peritt.
David Peritt previously worked as Founder and CSO at Lupagen and Adjunct Professor at Northwestern University. David Peritt holds Doctor Of Philosophy (Ph.D.), Immunology from University Of Pennsylvania.
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Compared to traditional cell therapy such as CAR-T, in vivo Gene Therapy creates a simple drug model that is not encumbered by cell therapy manufacturing limitations. The ability to genetically modify (gene therapy) immune cells in the body will significantly lower cost, complexity and increase safety thus broadening access in oncology and expanding gene therapy into many more indications. However, the ability to deliver genetic payloads specifically to immune cells with minimal off target impact (safety) and with the ability to redose (efficacy) remain significant challenges and limit the huge potential of gene therapy for the creation of therapeutic cells. Lupagen has created a delivery device to address these challenges. At the bedside, peripheral blood immune cells are removed for a short time, incubated with the gene delivery vehicle and returned to the patient in a closed loop extracorporeal system similar to dialysis or plasmapheresis. Lupagen partners with biopharma companies to develop their in vivo gene therapy programs by supplying extracorporeal delivery systems for preclinical and clinical studies. In the US this is regulated as a combination product similar to an auto-syringe where the biopharma company maintains full control over their product. Lupagen simply supplies the devices and disposables required for clinical testing and into commercialization. The cost saving compared to cell therapy manufacturing is immense.
Listed skills include Immunology, Biotechnology, Cell, Antibodies, and 22 others.
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Dallas, Texas, Us
Lupagen is enabling bedside cell therapy by creating a closed loop autologous cell modification system lowering costs and increasing patient safety and convenience.
Evanston, Il, Us
McCORMICK SCHOOL OF ENGINEERING. Industry advisory board, guest lecturer, co-op student advisor and curricula advisor for masters of biotechnology program.
Washington, District Of Columbia, Us
Gene modified allogeneic cell therapy for the delivery of therapeutic proteins implanted in an immune evading system. Built scientific team that in 2020 obtained IND/CTA clearance, first in human studies initiated, raised capital and took public on Nasdaq (SGTX).
New York, New York, Us
Research Program Lead for CAR-Tregs to move the patient experience from therapeutic to durable or curative responses for autoimmune diseases.
Lake Forest, Il, Us
Oversaw early biosimilar pipeline strategy, responsible for immunogenicity leading to FDA and EMA approvals for Retacrit, Inflectra, Nivestim and Nyvepria.
Lake Forest, Il, Us
Responsible for identifying, evaluating and championing strategic investments, acquisition and late stage development in the areas of regenerative medicine, oncology and hematology. Investments included Fate Therapeutics, Kiadis and ViaCyte.
New Brunswick, Nj, Us
Immune Cell Therapy Diligence Creating strategy and recommendations for J&J pharmaceutical division to coordinate cell therapies across organization.Co-founder, Immune Cell Therapy Incubator co-founded internal JNJ venture company to develop autologous regulatory T cell therapy for the treatment of immune mediated diseases. Responsible for business development, intellectual property, in-licensing and building research team of ~25.
Chief scientist and member of management team at Therakos. Led and managed research teams for the development of novel autologous cell therapies and team focused on improvements and clinical trials to expand indications for bedside cell therapy, photopheresis.
Us
Assisted in launch of infliximab - Remicade, the first marketed anti-TNF therapeutic with $10B+ in sales.Managed a unit responsible for the development of therapeutic antibodies including siltuximab - Sylvant (anti IL-6) and ustekinumab - Stelara (anti IL-12/23).
Philadelphia, Pa, Us
In the laboratory of Giorgio Trinchieri discovered NK1 and NK2 subsets, novel roles for IL-12 in driving IL-10 production and further characterized the CD244 receptor and its role as an HIV predictive marker for disease progression.
Us
Responsible for characterization of a novel IL-1 antagonist and determination of its viability as a therapeutic for the company.
Jerusalem, Il
Helped identify biological activity and characterization for a novel IL-1 inhibitor.
Arlington, Virginia, Us
Conducted research to understand the immunosuppressive properties of ethanol abuse.
Washington, Dc, Us
Assessed rare metal nutritional content for foods to be incorporated into the Handbook 8.
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David Peritt works for Lupagen.
David Peritt is listed as Enabling In-Situ Generation of Therapeutic Cells at Lupagen.
AeroLeads has found 1 work email signal at @pfizer.com for David Peritt at Lupagen.
AeroLeads has found 2 phone signal(s) with area code 224 for David Peritt at Lupagen.
David Peritt is based in Greater Chicago Area, United States while working with Lupagen.
David Peritt has worked for Lupagen, Northwestern University, Alliance For Regenerative Medicine, Korro Bio, Inc., and Guidepoint.
You can use AeroLeads to view verified contact signals for David Peritt at Lupagen, including work email, phone, and LinkedIn data when available.
David Peritt holds Doctor Of Philosophy (Ph.D.), Immunology from University Of Pennsylvania.
David Peritt is listed with skills including Immunology, Biotechnology, Cell, Antibodies, R&D, Medical Devices, Biopharmaceuticals, and Life Sciences.
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