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I am vice-president of research and development at Spheryx, an early-stage company commercializing holographic video microsopy. This new technology is used for analyzing suspensions of microparticles, such as protein aggregates in protein based medicines. I'm excited to bring innovative technology to the market.My background is in physics and I'm interested in finding ways ways to apply machine learning in a way that is good for people, organizations and the planet. I enjoy working with and leading agile teams and have a track record of delivering results. I believe we can make the most progress when we share knowledge, work together and have a playful spirit.
Spheryx, Inc.
View- Website:
- spheryx.solutions
- Employees:
- 13
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Vice President Of Research And DevelopmentSpheryx, Inc. Jan 2017 - PresentNew York, New York, United StatesManagement- Member of senior management team involved in decisions about new product ideas, personnel, and setting company priorities.- Led successful transition to Scrum for software team and took on scrum master role.Data science and machine learning- Implemented robust particle hologram detector using Darknet YOLO convolutional neural network: - Increased recall from 72% to 92% on a test dataset. - Improved detection of small particles leading to higher customer satisfaction.- Converted particle detector to Tensorflow and improved robustness with data augmentation.- Built machine learning processing pipeline and data tracking using DVC.Software- Built software that controls sample loading robot for our particle analyzer. - Worked on interface between application and robot firmware. - Led to sales for biopharmaceutical, highthroughput groups.- Leading project to make Spheryx software compliant with CFR 21 part 11 regulations, a key step needed for quality assurance applications.- Made interactive visualizations with PyQT and Dash to explore accuracy of analysis.Science and engineering- Manage relationship with NYU collaborators to find opportunities for tech transfer.- Published paper on multicolor holography and coauthor on seven other publications. -
Director Of Analytical Services And Research ScientistSpheryx, Inc. Feb 2015 - Jan 2017Greater New York City AreaScience and Engineering- Developed commercial holographic particle characterization instrument.- Supervised scientists analyzing customer samples and prepared customer reports.Software- Set up SQL database and file store to keep track of experimental data.- Encouraged the adoption of software best practices such as pair-programming, a team style guide, automated tests, and a team git workflow.- Sped up academic python analysis code by 180x
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Research AssistantNew York University Jun 2010 - Jan 2015I worked with David Grier, and studied optical forces in complex beams of light. Essentially we focused a powerful laser through a microscope objective and observed how the light moves tiny beads, which are about the size of a bacteria. We discovered that it is possible to use the polarization of the light to gain greater control over the optical forces. In addition we studied how light can not only push but also can pull small objects. We made such tractor beams on the microscale and are interested in understanding how to create long range tractor beams. -
Teaching AssistantNew York University Sep 2009 - May 2012General Physics I (Lab instructor) - Fall 2009Quantum Mechanics - Fall 2010Graduate Electricity and Magnetism - Spring 2012 -
Research AssistantRutgers University Sep 2008 - Aug 2009I worked with Haruo Kojima and studied solid He4 at low temperatures. We measured the effect of He3 impurities to better understand behavior that was thought to be caused by supersolidity. -
Research InternRutgers University May 2008 - Aug 2008Advisor: Prof. Robert Bartinski, Study of metallic quantum wells in thin metallic films.
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Frequently Asked Questions about David Ruffner
What company does David Ruffner work for?
David Ruffner works for Spheryx, Inc.
What is David Ruffner's role at the current company?
David Ruffner's current role is Vice-President of Research and Development at Spheryx, Inc..
What is David Ruffner's email address?
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What is David Ruffner's direct phone number?
David Ruffner's direct phone number is +190881*****
What schools did David Ruffner attend?
David Ruffner attended New York University, Rutgers, The State University Of New Jersey-New Brunswick.
What skills is David Ruffner known for?
David Ruffner has skills like Physics, Research, Matlab, Idl Programming, Teaching, Laser, Laboratory, Latex, Mathematica, Spectroscopy, Mathematical Modeling, Science.
Who are David Ruffner's colleagues?
David Ruffner's colleagues are Tiffany Markus, Nancy Pearson, Juliana Lumer, Paula Seraphim, Nancy Pearson, David Grier.
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