David T. Crowe, Ph.D. Email & Phone Number

Accomplished cell and molecular biologist that leads drug discovery teams in target selection, validation, optimization, and pre-clinical development. Broad experience:• Leadership positions in start-up, virtual and established biotech companies.• Successfully advanced multiple therapeutic modalities (small molecules, antibodies, and oligonucleotides) from discovery to in vivo PoC.• Prepared and presented company communications to Board, Sr. Management, collaborators, SAB, potential partners and investors.• Strong therapeutic focus in autoimmune, fibrotic, and neurodegenerative indications.• Directed research efforts for clinical product development teams, designed ex vivo pharmacodynamic assays, monitored use in a Phase I study.• Designed and directed manufacturing, assay development, and in vivo PoC studies by CROs, corporate, and academic collaborators.• Demonstrated leadership and mentoring skills that promote autonomy, creativity and critical thinking within the team to achieve high productivity and informed decisions.Specialties:Target Selection & Validation | Cell-based Assays | Cell-Surface Receptor Biology | CRO | Start-up | T-cell Function | microRNAs & antimiRs | Xenograft Studies | Project Management | Fibrosis | Autoimmune Disease | Oncology | siRNA | In Vivo PoC | Assay Development | Cell Trafficking | Drug Biodistribution | Drug Development | Immunology |

Listed skills include Drug Discovery, Biotechnology, Immunology, Drug Development, and 24 others.