David Tran Email & Phone Number

Berkeley, CA, US

Berkeley, California, US

• Tech transfer from bench scale to pilot scale bioreactors (1 - 2000L)
• Perfusion process development utilizing hollow fiber and centrifuge separation devices
• Process improvement spanning upstream development all the way to downstream processing including cell selection, media optimization, bioreactor optimization, material collection, etc.
• People management, talent development and operational excellence
• Building productive relationships between inter-departmental teams
• 6x Direct reports

Berkeley, California, US

• Clone selection, media optimization and process development resulting in up to 16x increase in productivity
• Established next-gen bench-scale adherent bioreactor platform from start to finish with continuous troubleshooting and improvement. Now our work-horse cultivator.
• Save $500k/year in spend on Benchling subscriptions by creating a custom bioreactor meta data aggregation system to function as our ELN and data lake
• Improved sensory attributes and raw material characteristics of our biomass for improved cultivated meat product quality
• 1x Direct Report

Berkeley, California, US

Development of novel adherent small scale bioreactors. Increased throughput by 7.5X while reducing set up time and experimental variability. Optimized process parameters that successfully transfered to pilot scale, significantly increasing yields and productivity.

Boston, Massachusetts, US

• Project lead (3 engineers, 2 biologists) to commercialize cardiac tissue measurement system with liquid perfusion
• Responsibilities include project management, programming, marketing, and SOP writing
• Project lead (3 engineers, 3 biologists) to design, fabricate and develop a new 96-well cardiac tissue culture plate
• Responsibilities include customer interfacing, project management, CAD, 3D prototyping, and data analysis
• CAD designed and fabricated bioreactor using rapid prototyping (3D printing/laser cutting) and machining
• LabVIEW software development for hardware interface of numerous acquisition and control devices

• Cardiac tissue engineering for next generation drug screening.
• Designed new bioreactor platform for long term imaging of cardiac organoid pump function
• Created prototype model using 3D CAD and laser cutting
• Coded LabVIEW interface for large array of cameras, valves and assorted hardware

Irvine, CA, US

• Experienced in culturing of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), and then differentiating these cells into cardiomyocytes using multiple protocols
• Created vascularized hiPSC-derived cardiac muscle tissue within a microfluidic PDMS device with controlled interstitial flow
• Studied cell metabolism and maturity in stem cell-derived cardiomyocytes encapsulated within cardiac-derived extracellular matrix using fluorescent lifetime imaging and phasor analysis
• Developed assays to analyze functional response (e.g. electrophysiology) of cardiac tissues to cardioactive drugs
• Studied cell metabolism and maturity in stem cell-derived cardiomyocytes using two-photon fluorescent lifetime imaging
• Collaborate with stem cell biologists, vascular biologists, microfluidic engineers, and electrical engineers

Deerfield, Illinois, US

• Optimized automated separations processes (filter presses, centrifuges, precipitation vessels) in a $400 million GMP facility using DeltaV and identifying root-cause issues
• Created and renovated software tools for cycle time monitoring, ensuring the completion of production deadlines

Doctor Of Philosophy (Phd) In Progress, Chemical Engineering

Bs, Chemical Engineering