Davis Ryman, Md Phd
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Davis Ryman, Md Phd Email & Phone Number

Chief Medical Officer at Aeovian Pharmaceuticals at Aeovian Pharmaceuticals
Location: Greater Chicago Area, United States, United States 13 work roles 3 schools
1 work email found @aeovian.com LinkedIn matched
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Current company
Role
Chief Medical Officer at Aeovian Pharmaceuticals
Location
Greater Chicago Area, United States, United States

Who is Davis Ryman, Md Phd? Overview

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Quick answer

Davis Ryman, Md Phd is listed as Chief Medical Officer at Aeovian Pharmaceuticals at Aeovian Pharmaceuticals, based in Greater Chicago Area, United States, United States. AeroLeads shows a work email signal at aeovian.com and a matched LinkedIn profile for Davis Ryman, Md Phd.

Davis Ryman, Md Phd previously worked as Chief Medical Officer at Aeovian Pharmaceuticals and Chief Medical Officer at Levo Therapeutics. Davis Ryman, Md Phd holds Doctor Of Medicine (M.D.), Nih Medical Scientist Training Program (Mstp) from Case Western Reserve University School Of Medicine.

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*@aeovian.com
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Profile bio

About Davis Ryman, Md Phd

• Board-certified neurologist and geneticist with over 10 years of combined experience in the pharmaceutical and biotechnology industries and academic clinical and translational research in neurological and genetic disorders• Recent experience in clinical development of AAV9 gene therapies for neurologic disorders, including work on two global Phase 3 trials, successful Sakigake application (Japanese breakthrough therapy designation), and BLA and MAA applications, leading to 2019 FDA approval of ZOLGENSMA for spinal muscular atrophy• Prior experience in design and execution of eight Phase 1-3B clinical trials in Alzheimer's disease, Parkinson's disease, and rare/orphan neurologic disorders, including progressive supranuclear palsy (PSP), early-onset autosomal dominant Alzheimer’s disease (ADAD), and advanced Parkinson’s disease• Other accomplishments include clinical leadership of two programs through FDA Pre-IND briefing books and successful IND applications, two successful Orphan Drug Designation (ODD) applications, completion and management approval of Phase 1-3 clinical development plans for three assets in neurological indications, and pre and post-approval work on DUOPA™, a drug-device combination product which earned FDA approval and orphan drug designation in 2015 and Japanese approval in 2016 for treatment of advanced Parkinson’s disease

Listed skills include Clinical Trials, Neuroscience, Neurology, Clinical Research, and 23 others.

Current workplace

Davis Ryman, Md Phd's current company

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Aeovian Pharmaceuticals
Aeovian Pharmaceuticals
Chief Medical Officer at Aeovian Pharmaceuticals
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13 roles · 12 years

Davis Ryman, Md Phd work experience

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Chief Medical Officer

Current

Berkeley, California, US

Aeovian Pharmaceuticals is a biopharmaceutical company aiming to discover, develop and commercialize innovative therapeutics for the treatment of rare and age-related diseases, with lead compounds including several novel and highly selective small molecules that potently inhibit the mTORC1 pathway.

Nov 2022 - Present

Chief Medical Officer

Skokie, IL, US

Led clinical development of intranasal carbetocin (LV-101) and other pipeline programs for the treatment of Prader-Willi syndrome (PWS), through the 2022 acquisition of Levo Therapeutics

Jan 2022 - Nov 2022

Vice President, Clinical Development

Skokie, IL, US

Jun 2018 - Jan 2022

Executive Medical Director

Avexis, Inc.

Clinical development of AAV gene therapy treatments for rare and serious genetic neurological disorders, including spinal muscular atrophy, Rett syndrome, and amyotrophic lateral sclerosis (ALS) due to SOD1 mutations (through $8.7B acquisition by Novartis)

Apr 2017 - Jun 2018

Medical Director

North Chicago, Illinois, US

  • Led two Clinical Strategy Teams responsible for activities including development of translational strategy, Phase 1 and Phase 2/3 study designs and protocols, clinical development plans, and management presentations.
  • Study-designated physician for seven Phase 1 - Phase 3B clinical trials of investigational drugs in progressive supranuclear palsy, Alzheimer’s disease, and Parkinson’s disease, including DUOPA™, a drug-device.
  • As part of AbbVie/Calico joint venture, completed evaluation and planning of translational and early clinical development programs in indications associated with aging
  • Therapeutic area expert for review of inlicensing, acquisition, and venture capital investment opportunities in neuroscience indications, resulting in successful partnership with C2N Diagnostics in 2015 for clinical.
  • Member of Accelerating Medicines Partnership (AMP-AD) NIH-industry working groups on tau PET imaging and validation of novel plasma biomarkers
  • Member of Alzheimer’s Disease Neuroimaging Initiative Private Partner Scientific Board (ADNI-PPSB) joint industry-academic working groups on computerized cognitive testing, amyloid PET and tau PET imaging
2014 - 2017 ~3 yrs

Associate Medical Director, Neuroscience Development

North Chicago, Illinois, US

2014 - 2016 ~2 yrs

Clinical Research Fellow, Dian Pharma Consortium

Dominantly Inherited Alzheimer Network Trials Unit (Dian-Tu)
  • With research mentor Dr Randall Bateman, worked on the DIAN-OBS multicenter study and DIAN-TU, a multiple-arm Phase 2/3 double-blind randomized controlled multicenter clinical trial led and operationalized by the DIAN.
  • Supervised two research medical students and one postdoctoral fellow, leading to four peer-reviewed DIAN publications in Neurology, JAMA Neurology, and Lancet Neurology
  • Extracted patient information from 3 multicenter clinical trials and 137 peer-reviewed manuscripts to create a meta-analysis database with individual-level data on symptom onset and disease progression
  • With DIAN Biostatistics Core, conducted analyses of DIAN Observational Study (DIAN-OBS) data to establish evidence-based inclusion/exclusion criteria for trial enrollment, and evaluate associations between.
  • With DIAN Genetics Core, participated in startup and development of the DIAN Expanded Registry (DIAN-XR), and development and implementation of whole-exome sequencing protocols for study participants
Jun 2013 - Aug 2014

Graduate Student Researcher

Cleveland, Ohio, US

  • In the lab of AD geneticist Bruce T Lamb at the Cleveland Clinic, planned and completed genome-wide association studies identifying genetic loci modulating brain amyloid-beta levels as a quantitative trait in a.
  • Designed and completed pharmacogenomic studies characterizing genetic modifiers of the effects of statin and non-statin cholesterol-lowering drugs on brain amyloid metabolism
Jun 2002 - Jul 2007

Bioinformatics Scientist

Franklin Lakes, New Jersey, US

  • Following acquisition of Clontech Laboratories by BD Biosciences, continued work on contract research and cDNA microarray assay development with a cross-functional team of molecular biologists and bioinformaticians
  • Completed university extension coursework in computer science and Perl programming; successfully developed and implemented computational methods for rapid design of application-specific cDNA microarrays and.
Jul 1999 - Jul 2000

Research Associate

San Jose, California, US

  • Design, development and validation of cDNA microarray assay systems for high-throughput gene expression analysis
  • Planning and completion of contract research projects using cDNA microarrays in preclinical validation of candidate compounds for Berlex Pharmaceuticals and other pharmaceutical industry partners
Jul 1998 - Jul 1999

Research Assistant, Drosophila Genome Project

Berkeley, CA, US

  • As part of LBNL / Celera Genomics joint venture, assisted completion of high-throughput shotgun sequencing of the model organism Drosophila melanogaster, the first metazoan genome to be successfully sequenced
May 1997 - Jul 1998
3 education records

Davis Ryman, Md Phd education

Doctor Of Medicine (M.D.), Nih Medical Scientist Training Program (Mstp)

Case Western Reserve University School Of Medicine

Doctor Of Philosophy (Ph.D.), Molecular Genetics

Case Western Reserve University

Bachelor'S Degree, Biochemistry And Molecular Biology

University Of California, Berkeley
FAQ

Frequently asked questions about Davis Ryman, Md Phd

Quick answers generated from the profile data available on this page.

What company does Davis Ryman, Md Phd work for?

Davis Ryman, Md Phd works for Aeovian Pharmaceuticals.

What is Davis Ryman, Md Phd's role at Aeovian Pharmaceuticals?

Davis Ryman, Md Phd is listed as Chief Medical Officer at Aeovian Pharmaceuticals at Aeovian Pharmaceuticals.

What is Davis Ryman, Md Phd's email address?

AeroLeads has found 1 work email signal at @aeovian.com for Davis Ryman, Md Phd at Aeovian Pharmaceuticals.

Where is Davis Ryman, Md Phd based?

Davis Ryman, Md Phd is based in Greater Chicago Area, United States, United States while working with Aeovian Pharmaceuticals.

What companies has Davis Ryman, Md Phd worked for?

Davis Ryman, Md Phd has worked for Aeovian Pharmaceuticals, Levo Therapeutics, Avexis, Inc., Abbvie, and Dominantly Inherited Alzheimer Network Trials Unit (Dian-Tu).

How can I contact Davis Ryman, Md Phd?

You can use AeroLeads to view verified contact signals for Davis Ryman, Md Phd at Aeovian Pharmaceuticals, including work email, phone, and LinkedIn data when available.

What schools did Davis Ryman, Md Phd attend?

Davis Ryman, Md Phd holds Doctor Of Medicine (M.D.), Nih Medical Scientist Training Program (Mstp) from Case Western Reserve University School Of Medicine.

What skills is Davis Ryman, Md Phd known for?

Davis Ryman, Md Phd is listed with skills including Clinical Trials, Neuroscience, Neurology, Clinical Research, Drug Development, Bioinformatics, Medicine, and Clinical Development.

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