AxisPharm, a dedicated ADC linker product and service provider

• Managed the lead optimization of a Chronic Obstructive Pulmonary Disorder (COPD) program• Managed the focused peptides library synthesis project for Covx unit, Pfizer • Lead five Ph.D. level chemists and managed a battery related organosilane material library synthesis project, developed methods for P-, N- , C- and O-silanes and overcame challenges such as lack of stability and hard to purify – exceeded client expectation by successfully delivering more than 80 unique silane targets with>95% purity• Re-engineered a process to scale up of a pyrene derivative for a nano-optical/electrical device application• Managed an oncology pro-drug program and successfully delivered two pro-drug targets

• Kinase inhibitors for treatment of various cancers• Hit assessment – early drug discovery using SBDD• Lead optimization – from lead to candidate of interest and candidate selection

• GPR41 modulators for treatment of metabolic disease• The first total synthesis of a novel glutathione containing Eicosanoid • GDIR/GPR119 agonist backup programs for treatment of type 2 diabetes• Development of potent cannabinoid receptor modulators for the treatment of inflammatory and neuropathic pain

• Combinatorial synthesis of heterocycle libraries consist of 24,000 compounds for the therapeutic application of stem cells• Optimization of small molecule drugs to stimulate tissue and organ regeneration