Dawn Thompson Email and Phone Number
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I’m a senior scientist and corporate vice president with 20+ years of experience leading collaborative teams through cutting-edge exploration in the fields of biology, genetics, and genomics. Building technology platforms for early-stage companies from the ground up, I’ve developed innovative techniques across the pharmaceutical, living medicine, commodity chemical, and agricultural industries. I drive stakeholder engagement, designing business strategies that raised $100M+ for multiple companies through investor financing and strategic relationships with Fortune 500 partners. Recognized for my contributions to innovation and mentorship, I’ve received awards and grants from the National Institutes of Health, the Genomic Centers for Infectious Disease, and the Broad Institute. I’m an active international presenter, advisory board member, and editorial board member, and have authored and contributed to 30+ publications. I continuously explore new frontiers blending my expertise in evolution and genomics with an interest in microbes. As VP of Microbiology and Automation at LifeMine Therapeutics, I built scaled platforms for fermentation, strain engineering and next generation sequencing (NGS) to crack the evolutionary code of biosynthetic gene cluster encoded small bioactive molecules. As the head of NGS at Gingko Bioworks, I used state-of-the art methods to drive organism engineering, identifying common themes and design principles to create new organisms for our customers. I continue advancing the goal of innovation in biological engineering and identifying green alternatives that decrease costs, labor, and resource use.Key Accomplishments:• Initiated global conversations on scientific advancements as chair and speaker at 18+ international conferences, and scientific advisory board member at Genomics and SynBio Institutes. • Led collaborative effort between Gingko Bioworks and Fortune 500 partners, delivering technical success to customer’s in-house product. Received patent approval for engineered microbe deployed to production.• Developed powerful platform for comparative functional genomics at Broad Institute, constructing novel, experimental methods to study regulatory frameworks to elucidate principles of regulatory circuits evolution underlying cellular phenotypes.Specializations: microbiology, synthetic biology, CRISPR-based strain engineering, fermentation, automation, functional genomics, molecular genetics, NGS, RNA seq, ChIP seq, gene regulation, experimental evolution, single cell genomics, regulatory circuits, transcriptomics
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Svp, Head Of Platform DevelopmentEmpress Therapeutics Jun 2023 - PresentWatertown, Massachusetts, Us -
Vp, Head Of Microbiology And Automation At Lifemine TherapeuticsLifemine Therapeutics Sep 2019 - Aug 2023Cambridge, Ma, UsLeadership and Strategic Platform Design:• Manage $4M budget and 28 staff (research associates to directors), formulating technical strategies for projects advancing biopharmaceutical success through genomic drug discovery.• Drive development of “biology at scale” production pipelines across entire discovery platform from fermentation to sequencing, chemistry, and target engagement assays.• Built NGS platform, cracking evolutionary code of biosynthetic gene clusters in microbes that make bioactive small molecules toward therapeutics. To reduce hit to lead (H2L) time by half, from years to months.• Led cross-functional teams in strain collection and engineering, fermentation, automation, and laboratory information management system (LIMS) infrastructure. Scaled engineering of 8 strains/week to 300. -
Vp, Interim Head Of Synthetic BiologyLifemine Therapeutics Nov 2019 - Nov 2020Cambridge, Ma, UsDirected build out and operation of Bio-manufacturing foundry to accelerate discovery of bioactive molecule for therapeutics. Including high throughput automated Design, Build, strain engineering, Expression and NGS workflows. -
Chief Scientific OfficerDirected Genomics Mar 2019 - Sep 2019Watertown, Massachusetts, UsInnovation and Strategic Planning:• Led scientific vision and business strategy to create NGS and biosensor-based diagnostic assays for research, translational, clinical, and agricultural applications. Expanded reach to aquaculture applications. • Employed diagnostic technologies for crop genotyping and pathogen detection to deploy real time intervention strategies in the field, preventing catastrophic crop failure and economic impact.• Optimized molecular biology protocols to bridge gap between current technology and next generation solutions.Business Development and Partnerships:• Collaborated with executive leadership to develop strategic plan, identifying and cementing new partnerships that expanded company reach to nascent aquaculture applications. • Negotiated capital equipment coordination across teams, maximizing budget efficiency. -
Head Of Next Generation Sequencing, Senior Biological EngineerGinkgo Bioworks, Inc. Aug 2015 - Mar 2019Boston, Ma, UsAlliance Development, Management, and Technical Engineering:• Partnered with organizational leaders to solve cross-functional challenges unique to engineering novel organism factories to grow products by fermentation in pharma, agriculture, and electronics markets.• Built multidisciplinary team offering diverse portfolio of sequencing applications, including fully automated DNA sequencing, genome assembly, and RNA and microRNA sequencing.• Directed team of 11 staff and $2M budget to advance scientific vision, leading company engagement on DARPA Synergistic Discovery and Design (SD2) program.• Developed HT synthetic biology workflows for high throughput microbial strain engineering.Program Lead, External Partnerships -
Associate Director Cell Circuits ProgramBroad Institute Jan 2012 - Aug 2015Cambridge, Ma, UsLeadership, Team Management, and Partner Collaboration:• Directed 12-person team (BS to Ph.D. levels) in technological development of genome-scale molecular biology processes, generating high-quality data, biological insights, and data-driven decisions.• Liaised directly on new collaborations with Broad Technology Labs (BTL), expanding comparative regulatory circuit reconstruction from microbes to vertebrate models (mammals and Cichlid fish).• Led research activities of major program initiatives, including Center for Cell Circuits and NHGRI-funded Centers of Excellence in Genomic Science (CEGS), meeting all grant objectives and milestones.Innovation and Development:• Advanced scientific vision and technological development toward systematically defining genetic and molecular circuits of a wide range of cell types. Integral partner of MIT-Broad Foundry. • Developed CRISPR-Cas9 genome engineering in microbial and mammalian cells.• Applied microfluidic technologies for single-cell genomics to successfully meet DARPA grant milestones. Diversity, Equity, and Inclusion:• Mentored under-represented and underserved university students, guiding promising individuals through career exploration and professional development.• Recruited top talent as selection committee member for Diversity Initiative, securing grants for successful students accepted to graduate programs and STEM careers. -
Senior Group LeaderBroad Institute Sep 2006 - Aug 2015Cambridge, Ma, Us• Innovation and Project Management:• Pioneered the development of RNA-seq methodologies for transcriptome reconstruction and quantification based on short Illumina-sequencing reads from genomes of poorly characterized organisms• Served as project lead for single-cell transcriptomics in immune and microbial (yeast and bacterial) cells.• Developed methods (live microscopy and host-pathogen RNA seq) to study interactions of live pathogens with immune cells from single host-pathogen interactions to the population scale.• Targeted identification of both pathogen and host determinants that control infection.• Sequenced isolates sampled consecutively from patients clinically treated with antifungals. • Analyzed genetic dynamics that accompany the appearance of drug resistance during oral and systemic candidiasis in human HIV patients.• Identified novel antifungal drug targets.
Dawn Thompson Skills
Dawn Thompson Education Details
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Harvard UniversityCell/Cellular And Molecular Biology -
Institute Of Molecular Biology University Of OregonMolecular Biology -
University Of New HampshireBiology
Frequently Asked Questions about Dawn Thompson
What company does Dawn Thompson work for?
Dawn Thompson works for Empress Therapeutics
What is Dawn Thompson's role at the current company?
Dawn Thompson's current role is SVP, Head of Platform Development at Empress Therapeutics.
What is Dawn Thompson's email address?
Dawn Thompson's email address is dt****@****etx.com
What is Dawn Thompson's direct phone number?
Dawn Thompson's direct phone number is (617) 714*****
What schools did Dawn Thompson attend?
Dawn Thompson attended Harvard University, Institute Of Molecular Biology University Of Oregon, University Of New Hampshire.
What skills is Dawn Thompson known for?
Dawn Thompson has skills like Genetics, Genomics, Molecular Biology, Biochemistry, Biotechnology, Functional Genomics, Cell, Cell Biology, Sequencing, Assay Development, Bioinformatics, Molecular Cloning.
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