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Senior experienced biotechnology leader in innovative, startup-like environments. Accustomed to managing small teams in genomics and epigenetics; Completely independent investigator from design to benchwork to data. Interested in development and commercialization of novel NGS diagnostic assays, tools, and technologies for both clinical and veterinary applications.Contributed to: Aging and longevity (skeletal muscle stem cells in mouse models, DNA methylation~ age associations), EWAS studies (validation of targets associated with blood lipid traits), Animal models of hemostasis and thrombosis, Methylation arrays, characterization of colorectal cancer (WES, RNA-seq, Imaging mass cytometry panel dev), Copy number variation associations with disease, Characterization of methylation in autoimmune disease, Epigenetic programs of the CD4 locus in mouse models, liquid biopsy assay development (fragment, methylation), deconvolution (DNAMe based digital histology).Contributed to early launch of 4 startups in NGS genomics:1. Ubiquity Genomics (now part of BioDynami): custom targeted hybridization capture based sequencing using the CATCH-Seq platform for clinically relevant targets for validation and research; MHC-seq and KIR/LRC loci https://biodynami.com/targeted-sequencing/#targeted-sequencing-listing2. BioDynami: affordable NGS library prep tools and kits, novel bead based systems for automated library prep an extraction, nucleic acid quant, MSB-Seq platform, CATCH-seq https://biodynami.com/3. IMIDomics: multiomics profiling of all immune mediate inflammatory diseases, proprietary database of autoimmune data https://www.imidomics.com/about4. Vidium Animal Health: precision oncology in canine; multi-cancer early detection from plasma25 years of biotechnology experience, 15 years of genomics and NGS > Methylation, Cancer MCED Targeted, solution-hyb based sequencing, bisulfite and oxidative bisulfite, data processing and bioinformatics Trained in zebrafish, chick, and mouse models Interests:> Age-related DNA methylation changes, Tet-mediated demethylation mechanisms> Dev of reduced costs in targeted capture tools for NGS and high density methylation profiling> Molecular and cellular characterization of colorectal cancer for precision oncology, detection> cfDNA epigenetic assay development> T cell molecular profiling and tumor infiltration> autoimmunity> epigenetic associations and gene expression> Integration of multiple omic datasets for personalized medicine approaches, ML models
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Principal Scientist R And DTempus AiNorcross, Ga, Us -
Senior Data ScientistPath Fertility Nov 2024 - PresentSalt Lake City, Utah, Us -
Vp Applications And BdBiodynami Jun 2024 - PresentHuntsville, Al, Us -
Head Of Genomics Research And DevelopmentVidium Animal Health Jan 2023 - May 2024Phoenix, Arizona, Us -
Sr Staff Scientist R&DZymo Research Corp Oct 2018 - Jan 2023Irvine, California, UsLiquid biopsy Urine and plasma cell free DNA multi-cancer early detection epigenetics NGS assay R&DMethylation platform R&D NGS assay development Immunophenotyping epigenetic NGS assay development (methylation-based deconvolution)Sars-CoV-2 and viral targeted capture for NGS variant monitoring in wastewater and clinical samples. SBIR contract work. -
Senior ScientistIntermountain Healthcare Aug 2017 - Oct 2018Murray , Ut, Us*Implement genomics pipelines to facilitate use of bioinformatic data for effective development of personalized patient treatments within the Intermountain healthcare system*Implementation of imaging mass cytometry (Hyperion) for characterization of colorectal cancer, immune profiling, and mass cytometry for monitoring cancer immunotherapy*R&D, QC, assistance for refining whole genome, exome capture, and RNA-Seq, from FFPE; cell free DNA library preparation*Assistance to continually expand the translational science lab toward new technologies, capabilities, and resources that improve precision care based on novel integrated datasets*Contribution and service with a team-based goal emphasis in all research projects*Tissue processing, experimental design, and genomic data collection partnering with Intermountain healthcare's biorepository -
Project ManagerImidomics Inc. Dec 2016 - Jul 2017San Rafael, California, UsPart-time startup role:Sample receipt, processing for nucleic acid isolation and genomic assay prep on blood collections from patients with immune mediated inflammatory diseases; QC; Crohns, Ulcerative colitis, SLE, RA, Psoriatic arthritis. -
Senior Scientist, Absher/Myers LabsHudsonalpha Institute For Biotechnology Nov 2013 - Jul 2017Huntsville, Al, UsTargeted next gen sequencing of genomic regions exhibiting epigenetic associations with blood lipidsDetermination of percent DNA methylation at CpGs bearing strongest correlations with expression levels within genes associated with lipid metabolism Analyses of DNA methylation changes in young and old tissuesR&D in new targeted sequencing workflows and library quality control -
Postdoctoral AssociateHudsonalpha Institute For Biotechnology May 2009 - Nov 2013Huntsville, Al, UsIntegrative analysis of age-related DNA methylation changes across human blood, brain, kidney and skeletal muscle with methy27 and targeted bisulfite sequencing validationDevelopment of clone adapted template capture hybridization for targeted sequencing; SNP, CNV and CpG methylation analyses within 15 collaboration-based projects related to: lupus, mechanisms of T cell selection, cat melanism, glioma, psoriatic arthritis, cardiovascular disease, dietary fat -
ConsultantUbiquity Genomics Nov 2013 - Nov 2014Improvements to next gen library quality control for targeted bisulfite sequencing using the CATCH-Seq platform; improvements to target template screening
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Senior Postdoctoral FellowUniversity Of Washington Jan 2005 - Apr 2009Seattle, Wa, UsInvestigation of muscle stem cell self renewal in vitro; Primary culture of FACS sorted satellite cells for gene expression analyses; Comparison of intrinsic self-renewal capacity of adult stem cells between young and old animals; Pax3 gene function in satellite cells isolated from diaphragm -
Graduate StudentUniversity Of Texas Health Science Center At San Antonio Aug 1999 - Aug 2004San Antonio, Tx, UsBiochemical microassay characterization of zebrafish clotting factors prothrombin and the novel factor VIIi; microarray analysis of prothrombin knockdown embryos using antisense morpholino microinjection; in situ hybridization for extrinsic pathway clotting factor expression during zebrafish embryogenesis; -
Research AssociatePoint Loma Nazarene University Jan 1998 - Jul 1999San Diego, California, UsLab assistant for molecular biology, biochemistry, and microbiology coursesBiology tutor and exam preparationUndergraduate research investigating bacteriophage induced conversion of cell surface molecules; microbiology
Kenneth Day Skills
Kenneth Day Education Details
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Point Loma Nazarene UniversityBiology -
Graduate School Of Biomedical Sciences At The University Of Texas Health Science Center San AntonioCell And Developmental Biology
Frequently Asked Questions about Kenneth Day
What company does Kenneth Day work for?
Kenneth Day works for Tempus Ai
What is Kenneth Day's role at the current company?
Kenneth Day's current role is Principal Scientist R and D.
What is Kenneth Day's email address?
Kenneth Day's email address is kd****@****rch.com
What is Kenneth Day's direct phone number?
Kenneth Day's direct phone number is +120637*****
What schools did Kenneth Day attend?
Kenneth Day attended Point Loma Nazarene University, Graduate School Of Biomedical Sciences At The University Of Texas Health Science Center San Antonio.
What are some of Kenneth Day's interests?
Kenneth Day has interest in Science Writing, Backpacking, Playing With My Kids, Drumming, Photography, Music, Mountain Biking, Graphic Design.
What skills is Kenneth Day known for?
Kenneth Day has skills like Molecular Biology, Genomics, Biochemistry, Cell, Cell Culture, Dna Sequencing, Sequencing, Dna, Biotechnology, Animal Models, Stem Cells, Genetics.
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