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Therapeutic Antibody Engineering. High throughput cellular and biochemical assay development.
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Sr Scientist To Director, Antibody DiscoveryIgm Biosciences Feb 2015 - PresentMountain View, California, UsIdentified novel human antibodies from B cell cloning and hybridoma for 10 oncology, autoimmunity, and infectious disease targetsIncreased speed and throughput of expression and purification by miniaturization and automation with roboticsEngineered of our multimeric and multispecific of high avidity human antibodies for safety, efficacy, target delivery, stability, and expression INDs of therapeutic antibodies for oncology and infectious disease targets10 published works in multi-specific antibody engineering and infections diseases -Nasal Delivery of an IgM Offers Broad Protection from SARS-CoV-2 Variants Nature (2021). DOI: 10.1038/s41586-021-03673-2-Immunostimulatory Multimeric Binding Molecules: PTO 20230203119 (2023) -Multimeric Coronavirus Binding Molecules: PTO 20230058162 (2023), 20220267415 (2022) -Multivalent Hepatitis B Virus Antigen Binding Molecules: PTO 11535664 (2023) -Multimeric SARS-CoV-2 Binding Molecules: PTO 20220267415 (2023), 20220403009 (2022) -Modified Human IgM Constant Regions: PTO 11401337 (2023) -IgM Glycovariants: PTO 20220306760 (2022) -Modified Human IgM Constant Regions: PTO 20220340676 (2022) -IgM Fc and J-Chain Mutations: PTO 20210087273 (2021) -A bispecific IgM antibody format for enhanced T cell dependent killing with minimal cytokine releaseAACR #5664 (2020) -
Sr. Scientist, AdcExtend Biopharma 2013 - Feb 2015Methods for selecting evolved transpeptidases and use thereof for creating protein conjugatesWO 2015183986 A1
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Sr. Scientist, Hts Assay DevelopmentSutro Biopharma, Inc. 2011 - 2013South San Francisco, California, UsPositional Optimization of Non-Natural Amino Acids to Enable Discovery and Production of Single Species ADCs ADC Summit (2012) -
Scientist, Phage DisplayCatalyst Bioscience Inc 2010 - 2011
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Scientist, Anti-ViralAlios Biopharma 2009 - 20102-5a analogs and their methods of use WO 2011005595 A2
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R&D Scientist, HcvGenelabs Technologies (Glaxosmithkline) 2007 - 2009Us -
Scientist, NgsJoint Genome Institute 2004 - 2007Berkeley, California, Us -
Scientist, OncologyPpd 2000 - 2004Wilmington, Nc, UsTargets for controlling cellular growth and for diagnostic methods WO 2004076682 A2 -
Post-Doc DermatologyUniversity Of California, San Francisco Mar 1996 - May 2000San Francisco, California, UsRegulation of involucrin gene expression by calcium in normalhuman keratinocytes. Front. Biosci. 1996; 1:a16–a24. [PubMed: 9159190]Requirement of an AP-1 site in the calcium response regionof the involucrin promoter. J. Biol. Chem. 2000; 275(31):24080–24088. [PubMed: 10816578]Role of protein kinase C α in calcium induced keratinocytedifferentiation: defective regulation in squamous cell carcinoma. J. Cell. Physiol. 2003; 195(2):249–259. [PubMed: 12652652]
Dean Ng Skills
Dean Ng Education Details
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University Of California, San FranciscoEntrepreneurship/Entrepreneurial Studies -
University Of California, DavisMolecular Endocrinology -
University Of California, BerkeleyMicrobiology And Immunology
Frequently Asked Questions about Dean Ng
What company does Dean Ng work for?
Dean Ng works for Igm Biosciences
What is Dean Ng's role at the current company?
Dean Ng's current role is Director, Antibody Discovery.
What is Dean Ng's email address?
Dean Ng's email address is ng****@****ail.com
What is Dean Ng's direct phone number?
Dean Ng's direct phone number is +192521*****
What schools did Dean Ng attend?
Dean Ng attended University Of California, San Francisco, University Of California, Davis, University Of California, Berkeley.
What are some of Dean Ng's interests?
Dean Ng has interest in Investing.
What skills is Dean Ng known for?
Dean Ng has skills like Assay Development, Drug Discovery, Molecular Biology, Biochemistry, High Throughput Screening, Oncology, Antibodies, Dna, R&d, Protein Purification, Protein Chemistry, Cell Biology.
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