Sr Scientist To Director, Antibody Discovery
CurrentIdentified novel human antibodies from B cell cloning and hybridoma for 10 oncology, autoimmunity, and infectious disease targetsIncreased speed and throughput of expression and purification by miniaturization and automation with roboticsEngineered of our multimeric and multispecific of high avidity human antibodies for safety, efficacy, target delivery, stability, and expression INDs of therapeutic antibodies for oncology and infectious disease targets10 published works in multi-specific antibody engineering and infections diseases -Nasal Delivery of an IgM Offers Broad Protection from SARS-CoV-2 Variants Nature (2021). DOI: 10.1038/s41586-021-03673-2-Immunostimulatory Multimeric Binding Molecules: PTO 20230203119 (2023) -Multimeric Coronavirus Binding Molecules: PTO 20230058162 (2023), 20220267415 (2022) -Multivalent Hepatitis B Virus Antigen Binding Molecules: PTO 11535664 (2023) -Multimeric SARS-CoV-2 Binding Molecules: PTO 20220267415 (2023), 20220403009 (2022) -Modified Human IgM Constant Regions: PTO 11401337 (2023) -IgM Glycovariants: PTO 20220306760 (2022) -Modified Human IgM Constant Regions: PTO 20220340676 (2022) -IgM Fc and J-Chain Mutations: PTO 20210087273 (2021) -A bispecific IgM antibody format for enhanced T cell dependent killing with minimal cytokine releaseAACR #5664 (2020)