Deb Ranjan Banerjee, Ph.D Email & Phone Number

Durgapur, Wb, In

Durgapur Area, India

✔️ Principle investigator of the project entitled 'Development of the Epigenetic Drugs using computational and chemical biology approaches' funded by Research Initiation Grant (RIG), NIT Durgapur.

Bryan/College Station, Texas Area

✔️ Anti-cancer research (self-dependent or at minimum supervision) to analyze the details of the mechanism of DNA repair and epigenetics inside chromatin funded by Cancer Prevention Research Institute of Texas (CPRIT).✔️ Design and construction of recombinant nucleosomes and chromatin carrying site-specific histone post-translational modifications, DNA lesions, and other modifications, which are very biologically relevant tools for the development of novel drug targets and precision medicine.✔️ Carry out downstream and upstream processes of protein expression-purification in various expression systems (bacterial and insect).✔️ Development of various in-vitro assays to investigate the correlation between DNA repair and epigenetic changes inside chromatin architecture.✔️ Lead and mentor new students into the projects as a team leader.✔️ Maintenance and troubleshooting of automated protein purification system GE AKTA PURE FPLC.✔️ Organization, management, and updating of chemical inventory and radioactive materials inventory.✔️ Management, assignment, and overseeing of group jobs and group meetings.

Bryan/College Station, Texas Area

✔️ Initiated and led the chromatin regulation and DNA repair project from the very beginning of current group through knowledgeable hands-on skills in molecular biology, in-vitro assays, protein expression-purification, chromatin biology, bioinformatics/database analysis that resulted in first-authored paper in the JACS, and a promotion to the team leader (Associate Research Scientist) position to mentor new students into the projects.✔️ Excellent in recombinant DNA technologies as evident by construction of 2100bp highly editable chromatin DNA containing site-specific DNA modifications starting from the basic units.✔️ Establishment of low-cost in-vitro Chromatin reconstitution unit, standardization of the protocol and training of fellow colleagues to increase productivity and effectiveness of the system.✔️ Excellent enzyme assay development using UV-based and gel-based methods against various chromatin substrates.✔️ Weekly maintenance and occasional trouble-shooting of the instruments from leading brands such as GE AKTA PURE FPLC, and also training of fellow colleagues that resulted in cost reduction up to $8,000 per year.✔️ In-house preparation of costly proteins (bacterial and from insect cell) that resulted in cost reduction up to $10, 000 per year and increased the effective uses of resources.✔️ Excellent collaborations with other teams that maximized project management and time management.✔️ Mentored one graduate student and one undergraduate student to increase the staff skill up and staff retention.✔️ Organization of chemical inventory-updates and management of monthly group jobs that increased the productivity.✔️ Voluntary participation in ‘Chemistry open house’ outreach program to contribute to community.

Indian Institute Of Technolgy Kharagpur, India

✔️ Demonstrated strong knowledgeable skills in various biophysical-biochemical techniques (In-vitro assays, enzyme kinetics, MIC assays, calorimetry, metabolomics, buffer/media preparation), bioinformatics and data analysis, drug discovery, protein purification, cell culture, and in organic synthesis to explore new anti-tuberculosis drug targets that resulted in three first-authored publications, one patent, total $150,000 grant money (two grants), and generation of new ideas.✔️ Established the ‘exploration of the less-explored anti-TB target’ project with hard work, determination, collaboration, and team play.✔️ Expertise in different kinds of drug design and discovery strategies such as Structure-based, ligand-based, computational, polypharmacology, hit-to-lead.✔️ Excellent biophysical and biochemical skills including protein structure analysis, enzyme kinetics (hit-to-lead), calorimetry (binding parameters), mycobacterial growth inhibition (MIC) assays.✔️ Outstanding inter-department and inter-school collaborations that resulted in six publications, development of three new projects ideas and maximizes the project and time management.✔️ Direct involvement in two grant acceptances and in one patent filing as a leading investigator that increased the product sale.✔️ The departmental operator of GE ITC200 and training of fellow colleagues that resulted in cost reduction up to $8,000 per year.✔️ Mentoring of two undergraduate students that increased the staff skills, organic chemistry tutor for four semesters, and laboratory instructor for two semesters✔️ Excellent scientific writing: Manuscript writing, Thesis writing, Grant writing, Patent writing.

Kolkata Area, India

✔️ Organic synthesis of anti-cancer agents that was selected for best thesis.✔️ Organization of ‘Chemistry re-union’ and participation in the cultural program.✔️ Voluntary participation in the anti-superstition campaign led by the ‘Paschim banga vigyan mancha’ to contribute to the community..

Doctor Of Philosophy (Ph.D.), Chemistry

✔️ PhD work at joint collaboration between Organic Chemistry and Biotechnology Department. ✔️ Research area: Chemical biology/Medicinal.

Master’S Degree, Chemistry, 1St Class

✔️ Research area: Organic synthesis of anti-cancer agents. ✔️ Thesis title: Synthesis of homoallyl chlorides from 6-methyl chromanone.