Debayan Dey, M.Sc, Ph.D Email and Phone Number
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I am a structural biologist with a passion for leveraging experimental and computational techniques to address problems in antibiotic resistance mechanisms, bacterial pathogenesis, and immunology. I serve as an Assistant Professor in the Department of Biochemistry at Emory University School of Medicine in Atlanta, US. My research focuses on mechanistic studies of bacterial antibiotic resistance machineries to understand their structure and dynamics, with the aim of developing targeted inhibitors. I investigate two macromolecular complexes: Bacterial RND efflux pumps and Ribosomal RNA methyltransferases. Additionally, I study allosteric communication, mechanisms of gain and loss of function, and other structural dynamics in various clinically important proteins (Human OAS1, OASL, CARD11, Trm10) using computational methods.I work on developing first-of-class inhibitors against efflux pumps and RNA methyltransferases targeting clinically important antibiotic-resistant pathogens. My approach combines biophysical, biochemical, and structural techniques such as cryo-EM and X-ray crystallography. My computational methods include phylogenetics, computer-aided drug discovery, molecular dynamics simulations, protein engineering, and machine learning. By integrating experimental and computational approaches, I aim to uncover complex mechanistic insights.
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Assistant ProfessorEmory University School Of MedicineAtlanta, Ga, Us -
Assistant ProfessorEmory University School Of Medicine Jun 2024 - PresentAtlanta, Ga, Us -
Instructor (Faculty) Of BiochemistryEmory University School Of Medicine May 2022 - Jun 2024Atlanta, Ga, Us -
Postdoctoral Research ScientistEmory University School Of Medicine Jun 2017 - May 2022Atlanta, Ga, Us -
Cystic Fibrosis Foundation Postdoctoral FellowEmory University School Of Medicine May 2018 - Jun 2020Atlanta, Ga, UsResearch Project: 1. Biochemistry and Structural Biology of virulence factors responsible for Pathogen adhesion to lung epithelial cells.2. Drug development of antibiotic resistance breakers against ESKAPE pathogens.3. Crystallography and Cryo-EM of Macromolecular complexes of Pseudomonas 4. Study of tRNA-Protein interaction using Biophysical and biochemical methods -
Fellow Of Cystic Fibrosis Scholar ProgramChildren'S Healthcare Of Atlanta Aug 2019 - Jun 2021Atlanta, Georgia, UsThe goal of the CF Scholars Program is to recruit, educate, and mentor pre-doctoral and postdoctoral researchers and clinicians to become the next generation of academicians in cysticfibrosis research. By the completion of this program, participants should have gained anincreased understanding of CF and how to perform team science, enhanced theircommunication skills, and become patient and scientific advocates. The program includes indepth and frequent interactions between CF clinicians and CF scientists so the trainee will beeducated on the important role each plays in the lives of the CF patient and their family. -
Dbt-Reseach Associate (Scientist)Indian Institute Of Science (Iisc) Jan 2017 - Jun 2017Bangalore, Karnataka, InCurrently working in several structural biology projects related to bacterial infection and strategies to curtail them. 1. Understanding the structure, function and evolution of antibiotic resistance conferring rRNA Methyltransferases and development of novel antibiotics2. Understanding the specificity determining factors of Phosphoribosyltransferases 3. Structural and evolutionary studies on Bacterial flagellar Hook like proteinsMethods: Crystallography, Cloning,expression and purification of proteins, Computational modeling and Docking studies, enzyme kinetics using various spectroscopic methods, Phylogenetic analysis*Written DST-SERB grant along with Prof. Ramagopal for the study of Methyltransferases*Teaching and guiding various assignment for six PhD students in biological Sciences , PPISR -
Research Associate (Scientist)Indian Institute Of Science (Iisc) Aug 2016 - Jun 2017Bangalore, Karnataka, InResearch associate in the field of crystallography and structural biology. -
Ugc Meritorious Research FellowIndian Institute Of Science (Iisc) Aug 2009 - Jul 2016Bangalore, Karnataka, InPhD under the supervision of Prof. S. Ramakumar in Dept. of Physics, IISc. Research in Bio-Crystallography,Bioinformatics, Drug Design and Molecular EvolutionCollaborators: Prof. V. Nagaraja (President, JNCASR, Bangalore and MCB, IISc) in HU projectProf. Udupi Ramagopal (Associate Professor, PPISR) in Methyltransferase (Mtase) ProjectProf. D.N.Rao (Professor and Former divisional chairman of biological sciences, IISc) in Mtase ProjectProf. Satish Patil (SSCU, IISc) in Nanomaterial project -
Summer Research TraineeIndian Institute Of Science May 2008 - Aug 2008Bangalore, Karnataka, InSummer training under the guidance of Prof. S. Ramakumar, working in a self-constructed project on classification of Pi Turns in Proteins with Machine Learning Algorithms. -
Undergraduate Student ResearcherPresidency University, Kolkata Jul 2005 - Jul 2006Kolkata, West Bengal, InUnderstanding the geological, magnetic and atmospheric properties of Moon. A review work under the guidance of Prof. Buddhadev Banerjee, Professor of Geophysics, Presidency Collage and Ex- Director of Geological Survey of India. Presented a Seminar on MHD of Moon as a KCCSNS Associate
Debayan Dey, M.Sc, Ph.D Skills
Debayan Dey, M.Sc, Ph.D Education Details
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Emory University - Goizueta Business SchoolOrganizational Leadership -
Emory University - Goizueta Business SchoolManagement Certificate Program -
Indian Institute Of Science (Iisc)Structural Biology And Crystallography -
University Of CalcuttaBiophysics And Bioinformatics -
Presidency University, KolkataPhysics -
Kendriya Vidyalaya
Frequently Asked Questions about Debayan Dey, M.Sc, Ph.D
What company does Debayan Dey, M.Sc, Ph.D work for?
Debayan Dey, M.Sc, Ph.D works for Emory University School Of Medicine
What is Debayan Dey, M.Sc, Ph.D's role at the current company?
Debayan Dey, M.Sc, Ph.D's current role is Assistant Professor.
What is Debayan Dey, M.Sc, Ph.D's email address?
Debayan Dey, M.Sc, Ph.D's email address is de****@****ail.com
What schools did Debayan Dey, M.Sc, Ph.D attend?
Debayan Dey, M.Sc, Ph.D attended Emory University - Goizueta Business School, Emory University - Goizueta Business School, Indian Institute Of Science (Iisc), University Of Calcutta, Presidency University, Kolkata, Kendriya Vidyalaya.
What are some of Debayan Dey, M.Sc, Ph.D's interests?
Debayan Dey, M.Sc, Ph.D has interest in Children, Economic Empowerment, Civil Rights And Social Action, Education, Science And Technology, Hiking And Music, Playing Cricket And Chess, Singing, Human Rights, Health.
What skills is Debayan Dey, M.Sc, Ph.D known for?
Debayan Dey, M.Sc, Ph.D has skills like Biophysics, Bioinformatics, Molecular Biology, Computational Biology, Protein Purification, Protein Chemistry, Structural Biology, Drug Design, Computational Modeling, Crystallography, Molecular Modeling, Drug Discovery.
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