Deborah Scheffer Email & Phone Number

Lexington, Massachusetts, États-Unis

Watertown, Massachusetts, États-Unis

• Responsible for leading discovery project teams and define strategy, goals, decision making, and budget.
• Supported development candidate transition and progression into clinical development by planning and tracking activities in pharmacology, toxicology, ADME, and CMC.
• Drove coordination of cross-functional activities and promoted effective communications internally and externally (consultants, vendors, CROs, academics, partners), assisted internal process improvement.
• Assisted teams in business development activities (letter of intent, commercial partnership founding, study plans, execution and follow-up, key opinion leaders).
• Coached project team leaders and served as a key point person for team members.
• Established project management tools to facilitate portfolio management and effective communication between project teams and executive suite: dashboards, project review governance boards, resource allocation, database.

• Managed projects across modalities (biologics, gene therapy, LMW) from exploratory to clinical trial Phase 2a. In partnership with the project team leaders, drove the project strategy development and strategic.
• Tracked, managed, and communicated project milestones with associated budget requirements.
• Presented and supported team leaders for presentation at senior management boards.
• Assured continuous consistency of the operational plan with project strategy.
• Facilitation and minute writing of governance board meetings, program team meetings and workshops.
• Mentored and trained project management interns and project team leaders. Key contributor to Novartis Global Program Management Internship Program design.

Cambridge, Massachusetts, États-Unis

• Responsible for leading the in vivo pharmacology lab focused on developing drugs for hearing loss. Project team leader in multiple projects with extensive hands-on lab activities.
• Collaborated globally, cross-functionally, and cross-divisionally to develop lead therapeutic candidates (gene therapy and low molecular weight molecules).
• Oversaw operational aspects of projects: strategy, planning, execution, and risks.
• Responsible for the daily workflow of three team members by coaching and mentoring.
• Facilitated and established internal and external collaborations.
• Co-organized the department retreat in 2019.

Cambridge, Massachusetts, United States

• Provided project management support for two project team focused on developing gene therapy for hearing loss.
• Established gene therapy development plans, risk assessment and decision trees.
• Provided scientific, drug development and project management advice.
• Provided best practice guidance to establish and maintain high performing team.

Boston, - USA

• Generated the first RNA-seq datasets of FACS-sorted inner ear hair cells.
• Implemented, developed, optimized, and managed next generation sequencing (NGS) projects aimed at studying the transcriptome of murine FACS sorted inner ear hair cells.
• Developed and used inner ear specific mouse strains.
• Wrote publications and gave oral presentations at international conferences.
• Generated viral vectors (AAV, adenovirus) for gene therapy
• Used CRISPR genome editing technology to study the effect of genetic mutations on cell lines

Boston - USA

Neurocentre Magendie - Bordeaux - France

• Lead operational and strategic aspects of the study of Rac1 in planar cell polarity establishment in vestibulocochlear organs
• Perform ex-vivo gene delivery in mouse embryonic cochlea by electroporation
• Supervised a research engineer
• Taught molecular biology (associate's degree)

Phd, Biochemistry, Molecular And Cellular Biology

• Generated viral vectors (AAV, adenovirus) for gene therapy • Used CRISPR genome editing technology to study the effect of genetic.

Master Of Business Administration - Mba, Project Management And Leadership

2-year degree completed by independently writing a business plan for a biotech company and presenting it to a committee.

Master'S, Oncogenesis And Genetics Of Developmental Diseases

• Molecular and genetic analysis of human biological samples for asphyxiating thoracic dysplasia study • Performed prenatal diagnosis of.