Dr. Shiller was the Chief of Gynecology at Good Samaritan Hospital in Baltimore and then the founding director of the Women's Wellness Center at Northwest Hospital. She was previously a practicing gynecologist who specialized in pelvic and sexual pain and minimally invasive surgery. In 2009, she became the first robotic surgeon at her hospital and then in 2019 was the first surgeon in Maryland to offer Acessa, an innovative laparoscopic treatment for fibroids.In 2015, Dee-Dee included in her practice pharmaceutical medicine and began participating in Phase 2 and 3 clinical trials as principal investigator. She was involved in studies that helped to discover new products for contraception, pelvic pain, fibroids and hot flashes.In 2021, Dee-Dee joined AbbVie as a medical director and pricipal investigator where she oversees the direction, planning, execution, and interpretation of clinical trials and research activities for Phase 1 studies at the AbbVie Clinical Pharmacology Research Unit. In addition, she participates in cross-functional teams to generate, deliver, and interpret high-quality clinical data supporting overall product scientific and business strategy. She is also responsible for understanding the regulatory requirements related to clinical studies and global drug development and accountable for complying with these. In addition to routine responsibilities, she has volunteered to be the physician development program coordinator, where she has developed syllabus, education plan and training schedule for physicians considering embarking in full time pharma careers. She is also an active member of the international project with the Institute of Healthcare Improvement (IHI) Conception project. The purpose of the project is to provide documentation to describe and define the core data elements for optimal assessment of in utero exposures to medicines.