Deepa Rana Jamwal Email & Phone Number

Philadelphia, PA, US

Philadelphia, Pennsylvania, United States

• Successfully conducted immunogenicity risk evaluation of candidate AAV vectors in the development of an ocular gene therapy platform. This involved assessing immune and non-immune cell populations (myeloid cells, T.
• Exhibited strong leadership by coordinating cross-functional teams to develop a pivotal Immunogenicity Risk Assessment (IRA) document for pre-IND and IND filings.
• Immunology Subject Matter Expert in internal and external meetings, advising therapeutic teams on immunology-related questions for preclinical, clinical, and GLP-Tox studies. Proposed novel AAV immunogenicity.
• Led the introduction of spatial biology and high-content imaging techniques, enabling high-throughput identification of tissue-localized immune responses to AAV vectors in complex tissues, such as the eye.
• Championed the development, implementation, and successful transfer of novel in-vitro and ex-vivo PBMC/DC-T cell assays to CRO or relevant internal teams for predicting systemic AAV response.
• Analyzed, interpreted, integrated and presented complex data to internal and external stakeholders and upper management. Designed, optimized, validated and transferred immunoassays in support of cross-collaborative.

Tucson, Arizona

• Advanced autoimmunity research projects with focus on crosstalk of different immune cells such as dendritic cells, myeloid cells, and biomarker identification in Inflammatory Bowel Disease thateventually lead to.
• Served as a SME to provide research guidance and project leadership in identifying, advancing, and supporting the internal and external collaborations.
• Led the publication of multiple publications and a book chapter advancing the field of mucosal immunology.
• Developed, evaluated, optimized and implemented new laboratory protocols to meet project goals and objectives. Data presentation and reports on project status to department research in progress and to principal.
• Designed and conducted pilot studies for NIH grants. Actively supervising and managingundergraduate and graduate students, visiting scholars, and other trainees.
• Manager of the Flow Cytometry Facility at the Steele Children’s ResearchCenter. Responsible for the functioning and maintenance of Flow Cytometers (LSR Fortessa),training of new users for antibody panel design.

Tucson, Arizona Area

• Investigated intricate cross talk between immune cells involved in the development of chronic auto-inflammatory disorders of the gut, collectively known as Inflammatory Bowel Diseases (IBD; Crohn’s Disease and.
• Designed, conducted, optimized pilot studies for NIH grants, wrote protocols, abstracts, technical reports.
• Project & data management; data analysis, submissions and presentations of data for internal and external meetings and publications.
• Actively supervised and managed undergraduate and graduate students, visiting scholars, and other trainees.
• Trained students and research interns in Flow Cytometry.

Tucson, Arizona Area

• Led project in understanding the role of Dendritic cells in regulating inflammation in Colitis.
• Extensively worked on multi color Flow cytometry, Western blots, ELISA assays, microscopy, Immunohistochemistry, lentivirus production/transfection and Organoid culture.
• Expertise in mammalian cell culture including primary cell culture and generation of many stable cell lines.

Tucson (AZ), USA

Designed and conducted research to investigate Immunological basis of age-related vulnerability in biodefense and emerging infections using TCR repertoire evaluation.

Chandigarh Area, India

Designed and conducted research on investigating the defects in immune response in chronic viral infection, especially to understand the role of dendritic cells in predicting the response to antiviral therapy in chronic hepatitis C and B patients, using extensive multi-color flow cytometry, Immunoassays and molecular biology.Conducted national and.

-Conducted assays for prospecting botanical pesticides using various bioassays-Extensively worked with HPLC and GLC to investigate pesticide residues in plants and soil

Doctor Of Philosophy (Phd), Immunology

Activities and Societies: Cultural Secretary for Association of Basic Medical Scientists (2010-2011)Title of Thesis: “Study of dendritic.

Graduate Certificate In Regulatory Science, Regulatory Science