Tissue Engineering scaffolds of anisotropic 3D architecture.Funded by the UK Regenerative Medicine Platform.Projects include:* Investigating the osteogenic potential and influence of Electrospun PCL and PVPA scaffold on stem cells* Cell repulsive theromoresponsive polymer surfaces for the delivery of cells to specific target sites in vivo* The development of a tissue engineered construct to restore and regenerate Barretts Oesophagus* The development of a tissue… Show more Tissue Engineering scaffolds of anisotropic 3D architecture.Funded by the UK Regenerative Medicine Platform.Projects include:* Investigating the osteogenic potential and influence of Electrospun PCL and PVPA scaffold on stem cells* Cell repulsive theromoresponsive polymer surfaces for the delivery of cells to specific target sites in vivo* The development of a tissue engineered construct to restore and regenerate Barretts Oesophagus* The development of a tissue engineered platform technology for the restoration and regeneration of the anterior cruciate ligament* 3D Printing of cell-laden peptide hydrogels Show less

Investigating the use of a novel photo-curable polymer hydrogel for the encapsulation of hMSCs and their differentiation towards a nucleus pulposus-like cell type by mimicking the hypoxic and mechanical stimulation conditions. Development of a novel physiological bioreactor system providing optimal and consistent hypoxic conditions and mechanical stimulation for long term cultures. The curable polymer hydrogel would act as a delivery for stem cells to nucleus pulposus tissue and provide an… Show more Investigating the use of a novel photo-curable polymer hydrogel for the encapsulation of hMSCs and their differentiation towards a nucleus pulposus-like cell type by mimicking the hypoxic and mechanical stimulation conditions. Development of a novel physiological bioreactor system providing optimal and consistent hypoxic conditions and mechanical stimulation for long term cultures. The curable polymer hydrogel would act as a delivery for stem cells to nucleus pulposus tissue and provide an injectable therapy which would be minimally invasive as well as restore and regenerate the biomechanical and biochemical properties of NP tissue. Show less