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Biomedical scientist with background in protein biochemistry, microbiology, and genomics. Dedicated to research in oncology, genetic engineering, optimization of protein synthesis and stability.MAIN AREAS OF EXPERTISE:* Genome editing * Strain and protein engineering* Protein biochemistry and purification* Molecular and synthetic biology * Liquid handling systems* Assay development* Bioinformatics and statistics
Yale University
View- Company phone:
- (203)432-4113
- Company email:
- brita.belli@yale.edu
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ScientistYale UniversityHamden, Ct, Us -
ScientistYale University Jan 2003 - PresentGreater New York City Area• Engineered yeast, bacterial strains for expression of protein complexes.• Expressed, purified proteins, reconstituted protein ubiquitination in vitro.• Carried out proteomic screen to identify proteins targeted for ubiquitin-mediated degradation.• Characterized small interacting motifs responsible for protein instability.• Discovered de-ubiquitination enzyme that regulates stability of cell cycle proteins.• Database mining and bioinformatics analysis of gene expression and protein structure. -
Postdoctoral FellowYale University Sep 2000 - Jan 2003Greater New York City Area• Created and amplified genomic libraries, curated genomic databases.• Studied the role of protein phosphorylation in regulation of gene transcription.• Developed microarrays to analyze gene transcription on a genomic scale. • Designed protocol to detect protein phosphorylation of low abundant proteins. • Examined genomic changes in transcription in response to small molecules.
Denis Ostapenko Skills
Denis Ostapenko Education Details
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Life Sciences -
Virology
Frequently Asked Questions about Denis Ostapenko
What company does Denis Ostapenko work for?
Denis Ostapenko works for Yale University
What is Denis Ostapenko's role at the current company?
Denis Ostapenko's current role is Scientist.
What is Denis Ostapenko's email address?
Denis Ostapenko's email address is de****@****ale.edu
What is Denis Ostapenko's direct phone number?
Denis Ostapenko's direct phone number is +120378*****
What schools did Denis Ostapenko attend?
Denis Ostapenko attended Weizmann Institute Of Science, Weizmann Institute Of Science, Peter The Great St.petersburg Polytechnic University.
What skills is Denis Ostapenko known for?
Denis Ostapenko has skills like Protein Purification, Molecular Biology, Biochemistry, Bioinformatics, Cell Culture, Genetics, Dna, Molecular Cloning, Pcr, Protein Expression, Assay Development, In Vitro.
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Denis Ostapenko
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