Dennis M Walling, Md, Mmci, Fidsa Email & Phone Number

Chapel Hill, Nc, Us

Cambridge, Massachusetts, Us

Seres is a microbiome therapeutics company working to revolutionize treatment of diseases by modulating the function of the human microbiome.Head of Clinical Research, responsible for all strategic, medical, safety, and translational clinical development activities.Selected accomplishments:• Leading the translational and clinical research and development of multiple orally-administered microbiome therapeutics in the clinical pipeline.• Line management of a team of physicians and clinical scientists.• Leading medical and safety monitoring and data analysis for a first-in-human phase Ib study of an orally-administered microbiome therapeutic designed to reduce bacterial infections and graft-vs.-host disease in patients with a hematopoietic stem cell transplant.• Supporting the post-authorization clinical development and safety surveillance of VOWST, the first orally-administered microbiome therapeutic approved for the prevention of recurrent Clostridioides difficile infection.

Durham, Nc, Us

BioCryst is a drug discovery, development, and commercial stage biopharma company focused on antiviral therapies and novel oral medicines for rare diseases.Responsible for medical, safety, scientific, and strategy input for all clinical development programs.Selected accomplishments:Viral Disease Indications: • Led the medical translational, non-clinical, and clinical development strategy program of an antiviral for Marburg virus.• Led the clinical development of phase I/II programs of an antiviral for SARS-CoV-2/COVID-19 and Yellow Fever.• Led the phase IV post-approval clinical development and safety monitoring of Peramivir, an antiviral for Influenza.Rare Disease Indications: • Led the medical translational and phase I/II/III clinical development strategy for a small molecule complement inhibitor.• Led the medical translational and phase I/II/III clinical development strategy for a small molecule kinase inhibitor.

Durham, Nc, Us

Chimerix was a pre-clinical and clinical stage drug discovery and development company focused on therapies for serious viral diseases with unmet medical needs. Responsible for medical, safety, and scientific input for all clinical development programs.Selected Accomplishments:• Led medical, safety, and scientific efforts for a first-in-human phase I study of an oral antiviral for Norovirus.• Co-led medical, safety, and scientific efforts supporting multiple phase Ib and IIa studies of an intravenous antiviral for Adenovirus.• Provided medical and safety support for a phase IIb/III study and the expanded access program of an oral antiviral for Adenovirus.• Initiated redesign of internal pharmacovigilance and medical safety processes, improving quality and completeness of safety data.• Co-mentored UNC Kenan-Flagler Business School team project in strategic market value analysis for new antiviral indications.

Durham, North Carolina, Us

IQVIA is a global human data science company engaged in biopharmaceutical research and development, healthcare data analytics, and integrated healthcare services.Responsible for medical, clinical, and scientific advisory expertise across all divisions, and medical safety review and analytic services for worldwide clinical trials and post-approval monitoring of pharmaceuticals and medical devices.Selected Accomplishments:• Achieved a 25% increase in medical review efficiency by creating a new industry “Best Practice” approach to developing quality medical content of clinical trial individual case safety reports through structured safety review and query.• Developed quality improvement trainings and job efficiency tools that enhanced productivity of the medical safety team.• Worked on developing digital technology platforms and automated pharmacovigilance tools to improve clinical trial performance.• Developed a “Best Practice” tuberculosis risk assessment and mitigation for clinical trial protocols with immunomodulatory drugs.• Designed and implemented a bespoke medical safety service with a pharmaceutical sponsor for a global development program.

Caduceus Biomedical Consulting is a biopharmaceutical and academic client consulting service.Responsible for delivery of the contracted scope of work.Selected Accomplishments:• Delivered research study design, clinical data review, and medical safety data review for clinical trials, and created original content for results presentation, publication, and pharmaceutical label development, for multiple global pharmaceutical companies.

Galveston, Texas, Us

UTMB is a major academic medical center engaged in healthcare service delivery, biomedical research, and medical education.Responsible for translational scientific research, clinical patient care, medical education, and administration of multiple institutional programs.Selected Accomplishments:• Developed a competitively-funded translational research program in EBV pathogenesis and oncogenesis, serving as Principal Investigator on multiple collaborative research projects, including investigator-initiated, multi-institution, NIH-funded, clinical trial.• Directed and managed own translational molecular virology research laboratory with staff, students, and post-doctoral fellows.• Organized a novel international scientific meeting on oral viral pathogenesis and oncogenesis, with a budget exceeding $100,000.

Chapel Hill, North Carolina, Us

UNC is a major hospital and healthcare delivery system affiliated with an academic medical center.Responsible for internal medicine and infectious diseases primary and consultative inpatient and outpatient medical services.

Master Of Management In Clinical Informatics

Clinical And Research Fellowship Training: Infectious Diseases And Viral Pathogenesis

Internship And Residency Clinical Training: Internal Medicine

Doctor Of Medicine, Medicine

Bachelor Of Science, Biology