Devinder Ubhi Email & Phone Number
@igmbio.com
3 phones found area 510
LinkedIn matched
Who is Devinder Ubhi? Overview
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Devinder Ubhi is listed as Director at IGM Biosciences, Inc., based in San Francisco Bay Area, United States. AeroLeads shows a work email signal at igmbio.com, phone signal with area code 510, and a matched LinkedIn profile for Devinder Ubhi.
Devinder Ubhi previously worked as Principal Scientist at Igm Biosciences, Inc. and Senior Scientist at Igm Biosciences, Inc.. Devinder Ubhi holds Doctor Of Philosophy (Ph.D.), Cell And Molecular Biology With An Emphasis In Biomolecular Structure And Function from The University Of Texas At Austin.
Email format at IGM Biosciences, Inc.
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AeroLeads found 1 current-domain work email signal for Devinder Ubhi. Compare company email patterns before reaching out.
About Devinder Ubhi
Excited to develop life saving biologics at all stages of drug development with hands-on experience from Phase 1 (IND) to Commercialization (BLA/MAA). 7+ years of technical (protein characterization & analytics), management and FDA regulatory experience in dynamic bay area startups and big pharma. Key member of a cross-functional team at Portola Pharmaceuticals which won BLA approval for AndexXa®, a recombinant modified human factor Xa (FXa) protein, and at IGM Biosciences for IND approval of IGM-8444, an anti-Death Receptor 5 IgM antibody. Currently in a growing Protein Analytics and Characterization group at IGM Biosciences developing innovative early and late stage IgM antibodies.
Listed skills include Protein Purification, Biotechnology, Enzyme Kinetics, Pcr, and 33 others.
Devinder Ubhi's current company
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Devinder Ubhi work experience
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Principal Scientist
CurrentAs a Principal Scientist I am responsible for overseeing early and late-stage drug development projects including formulation development, structural/biophysical characterization and analytical method development. Some key functions include:- Development of liquid formulation for IV and intranasal administration - Development of early stage analytical methods to enable clinical use of IgM antibodies- Characterization of IgM antibody structure, binding and function- Recent IND approval for IGM-6268 (intranasally administered IGM-6268, an anti-SARS-CoV-2 IgM monoclonal antibody)
Senior Scientist
IgM antibody formulation, analytics, characterization and tech transfer to support accelerated IND submissions - Supported IND submission for IGM-2323, a potential treatment of relapsed/refractory (r/r) B-cell non-Hodgkin lymphoma (NHL) in 2019 - CMC lead IGM-8444, an antibody targeting Death Receptor 5 (DR5) for the treatment of patients with solid and hematologic malignancies (IND approved in 2020)
Scientist Ii
Protein characterization and development scientist involved with BLA (AndexXa®) and MAA (IndexXa®) approvals during a dynamic clinical to commercial company phase transition - Led protein characterization projects to fill information gaps in breakthrough designation drug program - Developed and managed the validation of critical biochemical methods at various CROs including methods to establish identity and quantitate purity, product related variants, and impurities - Characterized degradation pathway and demonstrated overall protein analytics strategy was stability indicating - Successfully trained personnel and transferred technology (GMP methods) between CROs in USA and Europe - Skilled with data analysis using statistical software for trending, outlier identification and product specification - Contributed to the CMC sections of FDA and EU submissions (BLA, MAA, RFIs)
Scientist I
Postdoctoral Fellow
Elucidated the biochemical mechanism of the cobalamin-independent Methionine Synthase protein (Met6p), which is a key enzyme in fungal metabolism and a drug design target for Nosocomial Candidiasis, using structure/function studies (2015 publication) - Crystallized and solved the first substrate induced closed conformation resembling the likely transition state- Characterized the role of key amino acids in the active site by site directed mutagenesis and enzyme activity- Proposed the structural reorganization required for transition from the resting ‘open’ conformation to transient ‘closed’ conformation by systematically studying many substrate bound structures which showed substrate and metal ion induced structural rearrangements required for catalysis - Used Met6p protein structure expertise, virtual ligand docking programs and X-ray Crystallography to identify the compound, S-Adenosyl-L-Homocysteine, as drug scaffold for future anti-Met6p SAR studies
Graduate Student
Completed cross-disciplinary coursework (Molecular Biology, Cell Biology, Genetics, Biochemistry, Enzyme Kinetics)Tested the thesis that an inhibitor against an essential and structurally unique fungal enzyme called methionine synthase (Met6p) should selectively kill pathogenic fungi in blood stream infections with no harm to the host - Crystallized and solved the structure of the Met6p enzyme using protein engineering - Used a comprehensive drug discovery strategy to identify small molecule inhibitors against the Met6p target, including the development and use of high-throughput biophysical and kinetic screening assays, protein crystallization, and structure based drug design/screening- Characterized the Met6p active site using ligand bound structures and site-directed mutagenesis- Published 2 research papers- Trained, mentored and managed undergraduate researchers and lab technicians- Attended and presented research at national scientific conferences
Associate I In Qc Analytical Technology
Developed, optimized and validated a variety of analytical methods to support Novartis’ biopharmaceutical projects
Summer Intern
Investigated the secretion pathway of a highly expressed protein from Aspergillus oryzae relevant for biofuel research
Undergraduate Researcher
Investigated the presence and activity of the DNA repair proteins FPG and OGG in the chloroplast
Devinder Ubhi education
Doctor Of Philosophy (Ph.D.), Cell And Molecular Biology With An Emphasis In Biomolecular Structure And Function
Bachelor Of Arts And Science With Honors, German And Genetics
Frequently asked questions about Devinder Ubhi
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What company does Devinder Ubhi work for?
Devinder Ubhi works for IGM Biosciences, Inc..
What is Devinder Ubhi's role at IGM Biosciences, Inc.?
Devinder Ubhi is listed as Director at IGM Biosciences, Inc..
What is Devinder Ubhi's email address?
AeroLeads has found 1 work email signal at @igmbio.com for Devinder Ubhi at IGM Biosciences, Inc..
What is Devinder Ubhi's phone number?
AeroLeads has found 3 phone signal(s) with area code 510 for Devinder Ubhi at IGM Biosciences, Inc..
Where is Devinder Ubhi based?
Devinder Ubhi is based in San Francisco Bay Area, United States while working with IGM Biosciences, Inc..
What companies has Devinder Ubhi worked for?
Devinder Ubhi has worked for Igm Biosciences, Inc., Portola Pharmaceuticals, University Of Texas At Austin, Novartis, and Novozymes.
How can I contact Devinder Ubhi?
You can use AeroLeads to view verified contact signals for Devinder Ubhi at IGM Biosciences, Inc., including work email, phone, and LinkedIn data when available.
What schools did Devinder Ubhi attend?
Devinder Ubhi holds Doctor Of Philosophy (Ph.D.), Cell And Molecular Biology With An Emphasis In Biomolecular Structure And Function from The University Of Texas At Austin.
What skills is Devinder Ubhi known for?
Devinder Ubhi is listed with skills including Protein Purification, Biotechnology, Enzyme Kinetics, Pcr, Gel Electrophoresis, Drug Discovery, High Throughput Screening, and Molecular Biology.
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